Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Jason H. Kurzer"'
Autor:
Jason H. Kurzer, Olga K. Weinberg
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Next generation sequencing has uncovered several genes with associated mutations in hematologic malignancies that can serve as potential biomarkers of disease. Keeping abreast of these genes is therefore of paramount importance in the field of hemato
Externí odkaz:
https://doaj.org/article/285d1dbe616a46ff8b46a766dc12bc4c
Autor:
Chiou-Hong Lin, Stephen Hon-Kit Wong, Jason H. Kurzer, Corina Schneidawind, Michael C. Wei, Jesús Duque-Afonso, Johan Jeong, Xuhui Feng, Michael L. Cleary
Publikováno v:
Cell Reports, Vol 23, Iss 4, Pp 1166-1177 (2018)
Summary: Acute lymphoblastic leukemia (ALL) is associated with significant morbidity and mortality, necessitating further improvements in diagnosis and therapy. Targeted therapies directed against chromatin regulators are emerging as promising approa
Externí odkaz:
https://doaj.org/article/9ec9435c885040218a99c249ac02f40c
Autor:
Jason H. Kurzer, Olga K. Weinberg
Publikováno v:
Seminars in Diagnostic Pathology. 40:140-151
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::836b2df3840f184b26cc22568a928ca2
https://doi.org/10.1053/j.semdp.2023.04.002
https://doi.org/10.1053/j.semdp.2023.04.002
Data from E2A-PBX1 Remodels Oncogenic Signaling Networks in B-cell Precursor Acute Lymphoid Leukemia
Autor:
Michael L. Cleary, Michael C. Bassik, Stephen Hon-Kit Wong, Corina Schneidawind, Jason H. Kurzer, Jue Feng, Michael C. Wei, Kyuho Han, Chiou-Hong Lin, Jesús Duque-Afonso
There is limited understanding of how signaling pathways are altered by oncogenic fusion transcription factors that drive leukemogenesis. To address this, we interrogated activated signaling pathways in a comparative analysis of mouse and human leuke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8aa2306bbeb855d310e6f2c8620a9efa
https://doi.org/10.1158/0008-5472.c.6508719.v1
https://doi.org/10.1158/0008-5472.c.6508719.v1
Autor:
Michael L. Cleary, Michael C. Bassik, Stephen Hon-Kit Wong, Corina Schneidawind, Jason H. Kurzer, Jue Feng, Michael C. Wei, Kyuho Han, Chiou-Hong Lin, Jesús Duque-Afonso
Supplementary data provide further supportive evidence that E2A-PBX1 binds the regulatory regions of its target genes (Supplementary Figure 1), which are expressed in primary ALLs depending on karyotype (Supplementary Figure 2), and have oncogenic ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::272fbee84e4571a1d88402704cfd4ff4
https://doi.org/10.1158/0008-5472.22413468.v1
https://doi.org/10.1158/0008-5472.22413468.v1
Autor:
Miguel D. Cantu, Rashmi Kanagal-Shamanna, Sa A. Wang, Tapan Kadia, Carlos E. Bueso-Ramos, Sanjay S. Patel, Julia T. Geyer, Wayne Tam, Yazan Madanat, Peng Li, Tracy I. George, Meredith M. Nichols, Heesun J. Rogers, Yen-Chun Liu, Nidhi Aggarwal, Jason H. Kurzer, Danielle L.V. Maracaja, Eric D. Hsi, Feras Zaiem, Daniel Babu, Kathryn Foucar, Dorottya Laczko, Adam Bagg, Attilio Orazi, Daniel A. Arber, Robert P. Hasserjian, Olga K. Weinberg
Publikováno v:
JCO Precision Oncology.
PURPOSE Therapy-related acute myeloid leukemias (t-AML) are a heterogenous group of aggressive neoplasms that arise following exposure to cytotoxic chemotherapy and/or ionizing radiation. Many therapy-related myeloid neoplasms (t-MN) are associated w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33ae9f72e1dc52ba668376e768135f7d
https://doi.org/10.1200/po.22.00400
https://doi.org/10.1200/po.22.00400
Autor:
Robert P. Hasserjian, Karen M. Chisholm, Mina L. Xu, Olga K. Weinberg, Daniel Babu, Wayne Tam, Tracy I. George, Bartosz Grzywacz, Adam Bagg, Daniel A. Arber, Jason H. Kurzer, Sa A. Wang, Siddharth Bhattacharya, Wei Wang, Yuri Fedoriw, Kathryn Foucar, Attilio Orazi, Emily F. Mason, Chi Young Ok, Karen A. Moser
Publikováno v:
Modern Pathology. 34:1358-1366
Natural killer (NK) cells are lymphocytes of the native immune system that play a pivotal role in host defense and immune surveillance. While the conceptual view of NK-neoplasms is evolving, little is known about the rare NK lymphoblastic leukemia (N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a877219b5aef218ca237cb74bf6e884
https://doi.org/10.1038/s41379-021-00739-4
https://doi.org/10.1038/s41379-021-00739-4
Autor:
Maximiliano Ramia de Cap, Leo P. Wu, German A. Pihan, Damodaran Narayanan, Elizabeth A. Morgan, Geraldine S. Pinkus, Paola Dal Cin, Stephanie N. Hurwitz, Adam Bagg, Sanjay S. Patel, Wayne Tam, Madhu M. Ouseph, Jeffrey Gagan, Yazan F. Madanat, Alexa Siddon, Philipp W. Raess, Heesun J. Rogers, Carlos E. Bueso-Ramos, Rashmi Kanagal-Shamanna, Jason H. Kurzer, Daniel A. Arber, Robert P. Hasserjian, Olga K. Weinberg
Publikováno v:
Leukemia research. 123
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd5271780de235398c6c7914945bac3
https://pubmed.ncbi.nlm.nih.gov/36332291
https://pubmed.ncbi.nlm.nih.gov/36332291
Autor:
Jason H. Kurzer, Olga K. Weinberg
Publikováno v:
International journal of laboratory hematologyREFERENCES. 44
Acute leukemia is a heterogeneous disorder of hematologic malignancies composed primarily of hematopoietic precursors that have acquired unregulated self-renewal and proliferation. Hematology classification systems typically divide these neoplasms in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c7ef55588bf0462d1f70c202d1a0034
https://pubmed.ncbi.nlm.nih.gov/35770493
https://pubmed.ncbi.nlm.nih.gov/35770493
Autor:
Natasha Garamani, Bryan A. Stevens, Catherine A. Hogan, Malaya K. Sahoo, ChunHong Huang, Jason H. Kurzer, James L. Zehnder, Benjamin A. Pinsky
Publikováno v:
The Journal of Applied Laboratory Medicine
Background Numerous nucleic acid amplification assays utilizing different target genes of the SARS-CoV-2 genome have received emergency use authorization (EUA) by the United States Food and Drug Administration (FDA). Limited data are available compar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c24232cb206c2efc9883a28d50959af5
https://doi.org/10.1093/jalm/jfaa135
https://doi.org/10.1093/jalm/jfaa135