Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Jason G, Smith"'
Publikováno v:
PLoS Pathogens, Vol 20, Iss 6, p e1012317 (2024)
Mammalian α-defensins are a family of abundant effector peptides of the mucosal innate immune system. Although primarily considered to be antimicrobial, α-defensins can increase rather than block infection by certain prominent bacterial and viral p
Externí odkaz:
https://doaj.org/article/e3e8dcbe444b49d1976e4cd42e22efe1
Publikováno v:
BMJ Open, Vol 14, Iss 2 (2024)
Introduction Pharmacists provide a spectrum of services and comprehensive medication management for patients with substance use disorders (SUDs) with many providing timely and increased access to care for patients. Prior studies have evaluated other
Externí odkaz:
https://doaj.org/article/7a6fd30411184ee38db381e12be92d6f
Autor:
Barbara G Bokhour, Gemmae M Fix, Aishwarya Khanna, Ekaterina Anderson, Rendelle E Bolton, Marva Foster, Jason G Smith, Varsha G Vimalananda
Publikováno v:
BMJ Open, Vol 12, Iss 12 (2022)
Introduction Patient-centred care and care coordination are each key priority areas for delivering high quality healthcare. However, the intersection between these two concepts is poorly characterised. We theorise that greater advancements in healthc
Externí odkaz:
https://doaj.org/article/ed9ba6aace8d4de4816cb67c4ff804df
Publikováno v:
Pathogens and Immunity, Vol 4, Iss 2, Pp 196-234 (2019)
Background: Human papillomavirus (HPV) is linked to nearly all cases of cervical cancer. Despite available vaccines, a deeper understanding of the immune response to HPV is needed. Human α-defensin 5 (HD5), an innate immune effector peptide, blocks
Externí odkaz:
https://doaj.org/article/866ca3e07de1467585f071c8a6a7eedc
Autor:
Karina Diaz, Ciara T Hu, Youngmee Sul, Beth A Bromme, Nicolle D Myers, Ksenia V Skorohodova, Anshu P Gounder, Jason G Smith
Publikováno v:
PLoS Pathogens, Vol 16, Iss 11, p e1009018 (2020)
Enteric alpha-defensins are potent effectors of innate immunity that are abundantly expressed in the small intestine. Certain enteric bacteria and viruses are resistant to defensins and even appropriate them to enhance infection despite neutralizatio
Externí odkaz:
https://doaj.org/article/34c75e27d60c4474ac4664893017405b
Autor:
Jennifer L Sullivan, Anna Rae L Montano, Jaime M Hughes, Heather W Davila, Kelly A O’Malley, Ryann L Engle, Chelsea E Hawley, Marlena H Shin, Jason G Smith, Camilla B Pimentel
Publikováno v:
The Gerontologist. 63:405-415
Background and Objectives Dissemination-implementation.org outlines 110 theories, models, and frameworks (TMFs): we conducted a citation analysis on 83 TMFs, searching Web of Science and PubMed databases. Research Design and Methods Search terms were
Autor:
Jessica M. Porter, Mackenzi S. Oswald, Anjali Sharma, Shanan Emmanuel, Austin Kansol, Antonette Bennett, Robert McKenna, Jason G. Smith
Publikováno v:
Journal of Virology. 97
The ability of adeno-associated viruses (AAVs) to infect and deliver genetic material to a range of cell types makes them favorable gene therapy vectors. However, AAV vectors encounter a wide variety of host immune factors throughout the body, which
Autor:
Aishwarya Khanna, Gemmae M Fix, Ekaterina Anderson, Rendelle E Bolton, Barbara G Bokhour, Marva Foster, Jason G Smith, Varsha G Vimalananda
Publikováno v:
BMJ open. 12(12)
IntroductionPatient-centred care and care coordination are each key priority areas for delivering high quality healthcare. However, the intersection between these two concepts is poorly characterised. We theorise that greater advancements in healthca
Autor:
Sarah S Wilson, Beth A Bromme, Mayumi K Holly, Mayim E Wiens, Anshu P Gounder, Youngmee Sul, Jason G Smith
Publikováno v:
PLoS Pathogens, Vol 13, Iss 6, p e1006446 (2017)
The small intestinal epithelium produces numerous antimicrobial peptides and proteins, including abundant enteric α-defensins. Although they most commonly function as potent antivirals in cell culture, enteric α-defensins have also been shown to en
Externí odkaz:
https://doaj.org/article/fd2216afedea466ca68a6bbfd4d8888b
Autor:
Mayim E. Wiens, Jason G. Smith
Publikováno v:
mBio, Vol 8, Iss 1 (2017)
ABSTRACT α-Defensins are an important class of abundant innate immune effectors that are potently antiviral against a number of nonenveloped viral pathogens; however, a common mechanism to explain their ability to block infection by these unrelated
Externí odkaz:
https://doaj.org/article/e9d64c6635cc489d9798d32cccc05db1