Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jason Faris"'
Autor:
Hans Gelderblom, Patrick M Forde, Aung Naing, Matthew Taylor, Jennifer Mataraza, Marcus O Butler, Todd M Bauer, Justin F Gainor, Chia-Chi Lin, Sunil Sharma, Maria Ochoa de Olza, Andrea Varga, Jan H M Schellens, Hongqian Wu, Haiying Sun, Antonio P Silva, Jason Faris, Scott Cameron
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Spartalizumab is a humanized IgG4κ monoclonal antibody that binds programmed death-1 (PD-1) and blocks its interaction with PD-L1 and PD-L2. This phase 1/2 study was designed to assess the safety, pharmacokinetics, and preliminary efficac
Externí odkaz:
https://doaj.org/article/d6d1da80e61d43f995ed1d456acbc093
Autor:
Tobias Schmelzle, Emilie Chapeau, Daniel Bauer, Patrick Chene, Jason Faris, Cesar Fernandez, Pascal Furet, Giorgio Galli, Jiachang Gong, Stephanie Harlfinger, Francesco Hofmann, Eloisa Jimenez Nunez, Joerg Kallen, Thanos Mourikis, Laurent Sansregret, Paulo Santos, Clemens Scheufler, Holger Sellner, Markus Voegtle, Markus Wartmann, Peter Wessels, Frederic Zecri, Nicolas Soldermann
Publikováno v:
Cancer Research. 83:LB319-LB319
The YAP-TEAD protein-protein interaction (PPI) is a critical event known to mediate YAP oncogenic functions downstream of the Hippo pathway. Current advanced pharmacological agents which aim at inhibiting YAP-TEAD oncogenic function do so by engaging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad77e2db1f0369ac9729c839360bd713
https://doi.org/10.1158/1538-7445.am2023-lb319
https://doi.org/10.1158/1538-7445.am2023-lb319
Autor:
Steven Angelides, Melissa Lynne Johnson, Jason Faris, Reinhard von Roemeling, Elizabeth Martinez
Publikováno v:
Regular and young investigator award abstracts.
Background VISTA (V-domain Ig suppressor of T cell activation) is a key negative immune checkpoint regulator, locking T cells in a quiescent state, unlike PD1 and CTLA4, which are expressed on activated T cells. Preclinically, VISTA monoclonal antibo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36dbc8d4193c771eed3535a1e4e4cc4d
https://doi.org/10.1136/jitc-2020-sitc2020.0392
https://doi.org/10.1136/jitc-2020-sitc2020.0392
Autor:
Jason Faris, Elizabeth A. Maher, Murali Beeram, Mehdi Touat, Meredith Goldwasser, Nilofer Azad, Howard Burris, Timothy Cloughesy, Jonathan Trent, Ingo Mellinghoff, Sam Agresta, Bin Fan, Daniel Von Hoff, Patrick Wen, Lia Gore
Publikováno v:
Molecular Cancer Therapeutics. 14:PL04-05
Introduction: Somatic mutations in the metabolic enzymes isocitrate dehydrogenase (IDH) 1 and 2 occur in a spectrum of solid and hematologic malignancies. Mutant IDH1/2 in cancer cells results in the neomorphic production of the oncometabolite, D-2-h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84ffdd151f73094c78bbf89c89a72d9c
https://doi.org/10.1158/1535-7163.targ-15-pl04-05
https://doi.org/10.1158/1535-7163.targ-15-pl04-05
Publikováno v:
Ergonomics. 38:1779-1792
Twelve healthy male subjects were required to make speeded judgements concerning the orientation of visual stimuli while breathing air at reduced partial pressure in a hypobaric chamber at altitudes of 7000 and 12 000 ft. A control condition was also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76149650e2c5462c6b392fbc3696ac8f
https://doi.org/10.1080/00140139508925245
https://doi.org/10.1080/00140139508925245
Autor:
Jason, Faris
Publikováno v:
Work (Reading, Mass.). 31(1)
Nursing injuries are alarmingly high in the healthcare system. The rate of injuries adds to the shortage of nurses that are already employed. Preventing nursing injuries has focused on utilizing patient handling equipment. This project used post offe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::68996c873ed5c2ae50c1f71df9bcd0da
https://pubmed.ncbi.nlm.nih.gov/18820419
https://pubmed.ncbi.nlm.nih.gov/18820419
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