Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Jason E. Savage"'
Autor:
Anuradha A. Shastri, Anthony Saleh, Jason E. Savage, Tiziana DeAngelis, Kevin Camphausen, Nicole L. Simone
Publikováno v:
Nutrition & Metabolism, Vol 17, Iss 1, Pp 1-8 (2020)
Abstract Background Metastatic cancer is incurable and understanding the molecular underpinnings is crucial to improving survival for our patients. The IGF-1/Akt signaling pathway is often impaired in cancer leading to its progression and metastases.
Externí odkaz:
https://doaj.org/article/817a6a64532944a1a43ec4e8de079e8c
Autor:
Tu Dan, Anuradha A. Shastri, Ajay Palagani, Simone Buraschi, Thomas Neill, Jason E. Savage, Aastha Kapoor, Tiziana DeAngelis, Sankar Addya, Kevin Camphausen, Renato V. Iozzo, Nicole L. Simone
Publikováno v:
Cancers, Vol 13, Iss 4, p 888 (2021)
Breast cancer (BrCa) relies on specific microRNAs to drive disease progression. Oncogenic miR-21 is upregulated in many cancers, including BrCa, and is associated with poor survival and treatment resistance. We sought to determine the role of miR-21
Externí odkaz:
https://doaj.org/article/ab8d388477b64bb98e6ae95600784698
Autor:
Anthony D. Saleh, Jason E. Savage, Liu Cao, Benjamin P. Soule, David Ly, William DeGraff, Curtis C. Harris, James B. Mitchell, Nicole L. Simone
Publikováno v:
PLoS ONE, Vol 7, Iss 4 (2012)
Externí odkaz:
https://doaj.org/article/361a1237f7da449ab55c98bb827fc767
Publikováno v:
World Neurosurgery. 151:e995-e1001
Background Compensatory mechanisms in patients with adult spinal deformity (ASD) that lead to poor quality of life include positive sagittal balance and pelvic retroversion. The objective of this retrospective review was to identify demographic and r
Autor:
Jay A. Berzofsky, Kathy McKinnon, Kenneth Aldape, Jason E. Savage, Bryce Killingsworth, I Ghiran, Tim Traynor, Kevin Camphausen, Julia Kepley, Joshua A. Welsh, Jennifer Jones, Deven Appel, Alexander R. Ivanov
Publikováno v:
Nanoscale
Evidence continues to increase of the clinical utility extracellular vesicles (EVs) can provide as translational biomarkers. While a wide variety of EV isolation and purification methods have been implemented, few techniques are high-throughput and s
Autor:
Franz Ricklefs, Steven Jacobson, Matthew E. Roth, Katrin Lamszus, Tim F. Greten, Tomer Cooks, Jay A. Berzofsky, W. Marston Linehan, Asim B. Abdel-Mageed, Curtis C. Harris, Tim Traynor, Michelle Pleet, Cecile L. Maire, Sean Cook, Clotilde Théry, André Görgens, Hoyoung Maeng, Joshua A. Welsh, Min-Jung Lee, Jane B. Trepel, Kenneth Aldape, Maria J. Merino, Julia Kepley, Jennifer Jones, Aleksandar Milosavljevic, Jenn Marte, Alexander R. Ivanov, Bryce Killingsworth, Setty Magana, Eytan Ruppin, Amy K. LeBlanc, Kevin Camphausen, Ionita Ghiran, Mercedes Tkach, Jason E. Savage, James L. Gulley, Andrea B. Apolo
Publikováno v:
SSRN Electronic Journal.
Extracellular vesicles (EVs) of various types are released or shed from all cells. EVs carry proteins and contain additional protein and nucleic acid cargo that relates to their biogenesis and cell of origin. EV cargo in liquid biopsies of widespread
Autor:
Tiziana DeAngelis, Anuradha A. Shastri, Jason E. Savage, Anthony Saleh, Kevin Camphausen, Nicole L. Simone
Publikováno v:
Nutrition & Metabolism
Nutrition & Metabolism, Vol 17, Iss 1, Pp 1-8 (2020)
Nutrition & Metabolism, Vol 17, Iss 1, Pp 1-8 (2020)
Background Metastatic cancer is incurable and understanding the molecular underpinnings is crucial to improving survival for our patients. The IGF-1/Akt signaling pathway is often impaired in cancer leading to its progression and metastases. Diet mod
Autor:
David Bing Zhen, Jason E. Savage, Joshua M. Ruch, Kevin Camphausen, Diane M. Simeone, Kent A. Griffith, Mark M. Zalupski, Vaibhav Sahai, Edward J. Kim
Publikováno v:
Investigational new drugs, vol 34, iss 6
Invest New Drugs
Invest New Drugs
Background Cabozantinib and gemcitabine improve tumor control in pancreatic ductal adenocarcinoma (PDAC) in preclinical models through c-Met inhibition. We sought to determine the maximum tolerated dose (MTD) of this combination in patients with adva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fef9611dd4d43344519c5cae73c7609f
https://escholarship.org/uc/item/8089j2w4
https://escholarship.org/uc/item/8089j2w4
Autor:
James L. Gulley, Jason E. Savage, Joshua A. Welsh, Jennifer Jones, Jay A. Berzofsky, Kevin Camphausen
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 102:e172
Autor:
Yuri Sano, Meng Lim, Tu Dan, Nicole L. Simone, Jason E. Savage, James B. Mitchell, Richard G. Pestell, Anthony Saleh, Juan P. Palazzo, Frederica Sotgia, Brittany A. Simone, Michael P. Lisanti, Shuping Zhao, Colin E. Champ, Lianjin Jin, Kevin Camphausen
Publikováno v:
Cell Cycle
Dietary modification such as caloric restriction (CR) has been shown to decrease tumor initiation and progression. We sought to determine if nutrient restriction could be used as a novel therapeutic intervention to enhance cytotoxic therapies such as