Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jason E. Pike"'
Autor:
Holli M. Drendel, Jason E. Pike, Katherine Schumacher, Karen Ouyang, Jing Wang, Mary Stuy, Stephen Dlouhy, Shaochun Bai
Publikováno v:
Case Reports in Genetics, Vol 2015 (2015)
Medium-chain acyl-CoA dehydrogenase deficiency (MCADD) is an autosomal recessive disorder that leads to a defect in fatty acid oxidation. ACADM is the only candidate gene causing MCAD deficiency. A single nucleotide change, c.985A>G, occurring at exo
Externí odkaz:
https://doaj.org/article/1da832be1e794dd59bfaa169fbe9321b
Autor:
Christopher J. Schaeffer, Brian D. Justice, Mathew J. Devine, John M. Ventura, Jason E. Pike, Jeremy Donath, William B. Weeks
Publikováno v:
Joint Commission journal on quality and patient safety. 46(6)
In the United States, spine pain treatment is expensive and increasingly uses guideline discordant evaluation and treatment modalities, including magnetic resonance imaging (MRI), (1) up to 60% of which are considered inappropriate. (2) Inappropriate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a569291e7b76824da2cb2408a7d58043
https://pubmed.ncbi.nlm.nih.gov/32354627
https://pubmed.ncbi.nlm.nih.gov/32354627
Publikováno v:
J Gen Intern Med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8a987b2aeaf845032592c18f0bae6cb
https://doi.org/10.1007/s11606-019-04942-7
https://doi.org/10.1007/s11606-019-04942-7
Publikováno v:
Journal of Biological Chemistry. 285:41712-41723
Two pathways have been proposed for eukaryotic Okazaki fragment RNA primer removal. Results presented here provide evidence for an alternative pathway. Primer extension by DNA polymerase δ (pol δ) displaces the downstream fragment into an RNA-initi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::550efdb5c2e747d18cfc6cad8b036412
https://doi.org/10.1074/jbc.m110.146894
https://doi.org/10.1074/jbc.m110.146894
Publikováno v:
The Journal of biological chemistry. 285(53)
Two pathways have been proposed for eukaryotic Okazaki fragment RNA primer removal. Results presented here provide evidence for an alternative pathway. Primer extension by DNA polymerase δ (pol δ) displaces the downstream fragment into an RNA-initi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::84ff6088a0c775ecac1627f84cb60c32
https://pubmed.ncbi.nlm.nih.gov/20959454
https://pubmed.ncbi.nlm.nih.gov/20959454
Publikováno v:
The Journal of biological chemistry. 284(37)
We have developed a system to reconstitute all of the proposed steps of Okazaki fragment processing using purified yeast proteins and model substrates. DNA polymerase delta was shown to extend an upstream fragment to displace a downstream fragment in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c37a6cf6885ccd9a9f09a268589ecbda
https://pubmed.ncbi.nlm.nih.gov/19605347
https://pubmed.ncbi.nlm.nih.gov/19605347
Autor:
Peter M. J. Burgers, Marie L. Rossi, Judith L. Campbell, Robert A. Bambara, Jason E. Pike, Wensheng Wang
Eukaryotic Okazaki fragment maturation requires complete removal of the initiating RNA primer before ligation occurs. Polymerase δ (Pol δ) extends the upstream Okazaki fragment and displaces the 5′-end of the downstream primer into a single nucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd051a23fd141224fe916526518d2f8a
https://resolver.caltech.edu/CaltechAUTHORS:ROSjbc08
https://resolver.caltech.edu/CaltechAUTHORS:ROSjbc08
Publikováno v:
The Journal of biological chemistry. 281(43)
Bloom syndrome is a familial genetic disorder associated with sunlight sensitivity and a high predisposition to cancers. The mutated gene, Bloom protein (BLM), encodes a DNA helicase that functions in genome maintenance via roles in recombination rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c402e3b979932d2dc6b3858e22ac4cab
https://pubmed.ncbi.nlm.nih.gov/16950766
https://pubmed.ncbi.nlm.nih.gov/16950766