Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jason E Coleman"'
Autor:
Melissa L Williams, Jason E Coleman, Shannon E Haire, Tomas S Aleman, Artur V Cideciyan, Izabel Sokal, Krzysztof Palczewski, Samuel G Jacobson, Susan L Semple-Rowland
Publikováno v:
PLoS Medicine, Vol 3, Iss 6, p e201 (2006)
BackgroundLeber congenital amaurosis (LCA) is a genetically heterogeneous group of retinal diseases that cause congenital blindness in infants and children. Mutations in the GUCY2D gene that encodes retinal guanylate cyclase-1 (retGC1) were the first
Externí odkaz:
https://doaj.org/article/8d84b8df1c384746aff1d60ac92cb9b9
Autor:
Andrew Combes, David J. Keegan, Jason E. Coleman, Kate Coleman, Fatima Hamroush, Patrick Murtagh, Hector Franco-Penya, Patricia Fitzpatrick, Mary Aiken
Publikováno v:
Translational Vision Science & Technology
Purpose: Lens adapted smartphones are being used regularly instead of ophthalmoscopes. The most common causes of preventable blindness in the world, which are glaucoma and diabetic retinopathy, can develop asymptomatic changes to the optic nerve head
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69574152cb28458bc6769144a606f44f
https://doi.org/10.1167/tvst.10.8.1
https://doi.org/10.1167/tvst.10.8.1
Publikováno v:
Multiphoton Microscopy in the Biomedical Sciences XIX.
Two-photon microscopy (TPM) has shown its great impact in studying neuronal activity of live animals. Commercial TPM systems require the animals under study to be restrained under the microscope and the 3D images are obtained typically by using bulky
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e9407fb63223f022168a97f8877499b
https://doi.org/10.1117/12.2507655
https://doi.org/10.1117/12.2507655
Autor:
Matthew R. Sarkisian, Megan M. Le, George Ugartemendia, Lan Hoang-Minh, Tyler S. Smith, Alexander K. Parker, Jason E. Coleman, Eric W. Atkinson, Susan L. Semple-Rowland
Publikováno v:
Experimental Neurology. 282:119-127
Neonatal or early-life seizures (ELS) are often associated with life-long neurophysiological, cognitive and behavioral deficits, but the underlying mechanisms contributing to these deficits remain poorly understood. Newborn, post-migratory cortical n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87e0ae3140c9ffc9c113174efcd869cd
https://doi.org/10.1016/j.expneurol.2016.05.015
https://doi.org/10.1016/j.expneurol.2016.05.015
Autor:
Heui Chang Lee, Ray Ward, Janak Gaire, Seth Currlin, Andrew J. Woolley, Justin C. Williams, Jason E. Coleman, Kevin J. Otto
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
To screen the complex central nervous system (CNS) injury responses, we created a quadruple-labelled ‘PrismPlus’ mouse line with a genetically encoded distinct fluorescent tag in oligodendrocytes, microglia, neurons, and astrocytes. Cx3cr1-gfp an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b40169b3daaea169420b369627cf9e0
https://pubmed.ncbi.nlm.nih.gov/29739975
https://pubmed.ncbi.nlm.nih.gov/29739975
Publikováno v:
Biomedical Optics 2016.
A miniaturized 3D wearable PAT (3D-wPAT) technique is described for brain study in behaving animals. This 3D-wPAT technique has a considerable potential in neuroscience studies, such as behavior, cognition, and preclinical brain disease researches.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bc5e23698065174cb61b46173d35ec7
https://doi.org/10.1364/ots.2016.om2c.3
https://doi.org/10.1364/ots.2016.om2c.3
Autor:
Robert Haslinger, Alev Erisir, Marc Nahmani, Jeffrey P. Gavornik, Arnold J. Heynen, Mark F. Bear, Jason E. Coleman
Publikováno v:
Journal of Neuroscience. 30:9670-9682
Monocular lid closure (MC) causes a profound shift in the ocular dominance (OD) of neurons in primary visual cortex (V1). Anatomical studies in both cat and mouse V1 suggest that large-scale structural rearrangements of eye-specific thalamocortical (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b611aaf56882fbbf8f0bfaa57a79f21
https://doi.org/10.1523/jneurosci.1248-10.2010
https://doi.org/10.1523/jneurosci.1248-10.2010
Publikováno v:
PubMed Central
Ocular dominance (OD) plasticity is a classic paradigm for studying the effect of experience and deprivation on cortical development, and is manifested as shifts in the relative strength of binocular inputs to primary visual cortex (V1). The mouse ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55c8fe7f76f2e1b32754f34d35f194e3
https://doi.org/10.1016/j.neuroscience.2009.03.045
https://doi.org/10.1016/j.neuroscience.2009.03.045
Publikováno v:
Molecular Brain Research. 114:9-19
Retinal circadian oscillators regulate many aspects of retinal function. Investigations of these oscillators and the biochemical cascades that entrain them would be greatly facilitated if experimental paradigms could be identified that permit long-te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1745894f62b9d88ed53056be3dd46e7
https://doi.org/10.1016/s0169-328x(03)00122-0
https://doi.org/10.1016/s0169-328x(03)00122-0
Publikováno v:
Investigative ophthalmologyvisual science. 46(1)
PURPOSE. Light-driven translocation of phototransduction regulatory proteins between the inner and outer segments of photoreceptor cells plays a role in the adaptation of these cells to light. The purpose of this study was to examine the effects of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b23a01041bbbc0898e30b9a33cb9bb5e
https://pubmed.ncbi.nlm.nih.gov/15623748
https://pubmed.ncbi.nlm.nih.gov/15623748