Zobrazeno 1 - 10 of 111 pro vyhledávání: '"Jason E, Hein"'
1
Akademický článek
Phase transfer catalysts shift the pathway to transmetalation in biphasic Suzuki-Miyaura cross-couplings
Autor: Yao Shi, Joshua S. Derasp, Tristan Maschmeyer, Jason E. Hein
Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract The Suzuki-Miyaura coupling is a widely used C-C bond forming reaction. Numerous mechanistic studies have enabled the use of low catalyst loadings and broad functional group tolerance. However, the dominant mode of transmetalation remains co
Externí odkaz: https://doaj.org/article/e8e7d5570d0e4860ac12ac7a315680e6
Zobrazit plný text záznamu
2
Akademický článek
Ring walking as a regioselectivity control element in Pd-catalyzed C-N cross-coupling
Autor: Madeleine C. Deem, Joshua S. Derasp, Thomas C. Malig, Kea Legard, Curtis P. Berlinguette, Jason E. Hein
Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
The phenomenon of „ring-walking‟, wherein a metal catalyst remains bound to a pi system as it migrates to another coupling site, is supported largely by circumstantial evidence. Here the authors perform an in-depth kinetic study of Buchwald- Hart
Externí odkaz: https://doaj.org/article/365c13a15c8b45108a75443d68976c01
Zobrazit plný text záznamu
3
Akademický článek
Data-science driven autonomous process optimization
Autor: Melodie Christensen, Lars P. E. Yunker, Folarin Adedeji, Florian Häse, Loïc M. Roch, Tobias Gensch, Gabriel dos Passos Gomes, Tara Zepel, Matthew S. Sigman, Alán Aspuru-Guzik, Jason E. Hein
Publikováno v: Communications Chemistry, Vol 4, Iss 1, Pp 1-12 (2021)
An automated closed-loop system optimizes a stereoselective Suzuki-Miyaura reaction using a machine learning algorithm that incorporates unbiased and categorical process parameters.
Externí odkaz: https://doaj.org/article/fc4f62943ff64484b8d72e580bfeb7ba
Zobrazit plný text záznamu
4
Akademický článek
Two Fusarium copper radical oxidases with high activity on aryl alcohols
Autor: Maria Cleveland, Mickael Lafond, Fan Roderick Xia, Ryan Chung, Paul Mulyk, Jason E. Hein, Harry Brumer
Publikováno v: Biotechnology for Biofuels, Vol 14, Iss 1, Pp 1-19 (2021)
Abstract Background Biomass valorization has been suggested as a sustainable alternative to petroleum-based energy and commodities. In this context, the copper radical oxidases (CROs) from Auxiliary Activity Family 5/Subfamily 2 (AA5_2) are attractiv
Externí odkaz: https://doaj.org/article/b619b0bbe7d34920801c0459ef12420b
Zobrazit plný text záznamu
5
Akademický článek
Automated solubility screening platform using computer vision
Autor: Parisa Shiri, Veronica Lai, Tara Zepel, Daniel Griffin, Jonathan Reifman, Sean Clark, Shad Grunert, Lars P.E. Yunker, Sebastian Steiner, Henry Situ, Fan Yang, Paloma L. Prieto, Jason E. Hein
Publikováno v: iScience, Vol 24, Iss 3, Pp 102176- (2021)
Summary: Solubility screening is an essential, routine process that is often labor intensive. Robotic platforms have been developed to automate some aspects of the manual labor involved. However, many of the existing systems rely on traditional analy
Externí odkaz: https://doaj.org/article/f431d4d259a141f1bc9a1fd655a8c73b
Zobrazit plný text záznamu
8
Akademický článek
ChemOS: An orchestration software to democratize autonomous discovery.
Autor: Loïc M Roch, Florian Häse, Christoph Kreisbeck, Teresa Tamayo-Mendoza, Lars P E Yunker, Jason E Hein, Alán Aspuru-Guzik
Publikováno v: PLoS ONE, Vol 15, Iss 4, p e0229862 (2020)
The current Edisonian approach to discovery requires up to two decades of fundamental and applied research for materials technologies to reach the market. Such a slow and capital-intensive turnaround calls for disruptive strategies to expedite innova
Externí odkaz: https://doaj.org/article/76c3483475504d4cbef964a65abffa9e
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje