Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Jason Duncan"'
Autor:
Lauren M. Schmitt, Anna L. Arzuaga, Ashley Dapore, Jason Duncan, Maya Patel, John R. Larson, Craig A. Erickson, John A. Sweeney, Michael E. Ragozzino
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2023)
IntroductionFragile X Syndrome (FXS) is a monogenic condition that leads to intellectual disability along with behavioral and learning difficulties. Among behavioral and learning difficulties, cognitive flexibility impairments are among the most comm
Externí odkaz:
https://doaj.org/article/f6494fb72f27495ea31d50d278e1e483
Autor:
Adriana N. Schmidt, John P. Sundberg, Lloyd E. King, Susan R. Opalenik, F. Jason Duncan, Helen B. Everts, Kathleen A. Silva, David E. Ong
Publikováno v:
Nutr Res
Topical 17-beta-estradiol (E2) regulates the hair cycle, hair shaft differentiation, and sebum production. Vitamin A also regulates sebum production. Vitamin A metabolism proteins localized to the pilosebaceous unit (PSU; hair follicle and sebaceous
Autor:
Kevin Schenk, Adel Lari, Matthew Church, Eric Graves, Jason Duncan, Robin Miller, Neesha Desai, Richard Zhao, Duane Szafron, Mike Carbonaro, Jonathan Schaeffer
Publikováno v:
Proceedings of the AAAI Conference on Artificial Intelligence and Interactive Digital Entertainment. 9:170-176
As the video game industry grows, both developers and creative authors seek new ways to simplify the process of controlling story content using scripts. This paper describes a story model and its software implementation, ScriptEase II, designed to so
Autor:
Bartholomew J Naughton, F Jason Duncan, Darren Murrey, Tierra Ware, Aaron Meadows, Douglas M McCarty, Haiyan Fu
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80142 (2013)
Mucopolysaccharidosis (MPS) IIIB is a devastating neuropathic lysosomal storage disease with complex pathology. This study identifies molecular signatures in peripheral blood that may be relevant to MPS IIIB pathogenesis using a mouse model. Genome-w
Externí odkaz:
https://doaj.org/article/1765de5a86994bc2a248fcd3df484760
Publikováno v:
Clinical and Experimental Optometry. 104:874-875
Alport syndrome is an inherited X-linked collagen IV disorder (80-85% cases) associated with renal failure (99%), hearing loss (82.5%), and ocular findings (44-81%), most commonly involving the cor...
Autor:
Douglas M. McCarty, Christopher Shilling, Brad Bolon, William G. Bremer, Christopher M. Walker, Kimberly Zaraspe, Aaron S. Meadows, Chrystal L. Montgomery, Haiyan Fu, Kevin M. Flanigan, F. Jason Duncan, Kathryn Waligura, Marybeth Camboni, Bartholomew J. Naughton, Kim L. McBride
Publikováno v:
Human Gene Therapy Clinical Development. 26:228-242
No treatment is currently available for mucopolysaccharidosis (MPS) IIIB, a neuropathic lysosomal storage disease due to defect in α-N-acetylglucosaminidase (NAGLU). In preparation for a clinical trial, we performed an IND-enabling GLP-toxicology st
Autor:
Katie Campbell, Haiyan Fu, Darren A. Murrey, Bartholomew J. Naughton, Brad Bolon, Christopher M. Walker, Tierra Ware, Douglas M. McCarty, F. Jason Duncan, Krista M. D. La Perle, Kevin M. Flanigan, Kim L. McBride, William G. Bremer, Laurie Goodchild, Aaron S. Meadows
Publikováno v:
Human Gene Therapy Clinical Development. 25:72-84
No treatment is currently available for mucopolysaccharidosis (MPS) IIIB, a neuropathic lysosomal storage disease caused by autosomal recessive defect in α-N-acetylglucosaminidase (NAGLU). In anticipation of a clinical gene therapy treatment for MPS
Autor:
Helen B. Everts, Kathleen A. Silva, David E. Ong, Charles J. Johnson, John P. Sundberg, Joseph L. Napoli, Jinshan Wang, Benjamin L. King, Kevin J. McElwee, David A. Whiting, Sonya P. Kamdar, Jin P. Szatkiewicz, Lloyd E. King, F. Jason Duncan
Publikováno v:
The Journal of investigative dermatology
Alopecia areata (AA) is an autoimmune disease that attacks anagen hair follicles. Gene array in graft-induced C3H/HeJ mice revealed that genes involved in retinoic acid (RA) synthesis were increased, whereas RA degradation genes were decreased in AA
Publikováno v:
Journal of the American Society for Mass Spectrometry. 27(7)
Secular frequency scanning is implemented and characterized using both a benchtop linear ion trap and a miniature rectilinear ion trap mass spectrometer. Separation of tetraalkylammonium ions and those from a mass calibration mixture and from a pesti
Publikováno v:
International Journal of Mass Spectrometry. 305:69-73
Reduced power operation of a mass analyzer with minimum loss of spectral resolution and mass range is desirable in portable instruments. Miniaturizing quadrupole-based ion traps can be especially worthwhile since the RF amplitude necessary for mass a