Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jason Dapper"'
Autor:
Richard J. Gilbertson, Karen D. Wright, Christopher Calabrese, Thomas E. Merchant, R. Kipling Guy, Martine F. Roussel, Clinton F. Stewart, Arzu Onar-Thomas, Burgess B. Freeman, Yogesh T. Patel, Amar Gajjar, Hope E. Terhune, Sabrina Terranova, Anang Shelat, Michael DeCuypere, Jason Dapper, Brandon Bianski, Nidal Boulos, Birgit V. Nimmervoll
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d50b7bcca23a723f27cae670aa20ac6
https://doi.org/10.1158/1078-0432.22464386.v1
https://doi.org/10.1158/1078-0432.22464386.v1
Autor:
Richard J. Gilbertson, Karen D. Wright, Christopher Calabrese, Thomas E. Merchant, R. Kipling Guy, Martine F. Roussel, Clinton F. Stewart, Arzu Onar-Thomas, Burgess B. Freeman, Yogesh T. Patel, Amar Gajjar, Hope E. Terhune, Sabrina Terranova, Anang Shelat, Michael DeCuypere, Jason Dapper, Brandon Bianski, Nidal Boulos, Birgit V. Nimmervoll
Tumor proliferation measured as Ki67 index in (A) mSEP-CR(-)RTBDNb and (B) mCPC treated with the indicated dose and route of administration of gemcitabine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60162aaecd98cfb3af8b44dcec7c6d9a
https://doi.org/10.1158/1078-0432.22464389
https://doi.org/10.1158/1078-0432.22464389
Autor:
Richard J. Gilbertson, Karen D. Wright, Christopher Calabrese, Thomas E. Merchant, R. Kipling Guy, Martine F. Roussel, Clinton F. Stewart, Arzu Onar-Thomas, Burgess B. Freeman, Yogesh T. Patel, Amar Gajjar, Hope E. Terhune, Sabrina Terranova, Anang Shelat, Michael DeCuypere, Jason Dapper, Brandon Bianski, Nidal Boulos, Birgit V. Nimmervoll
information on drugs used in preclinical studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353cf3983d5121895cb71e166ea8e2d7
https://doi.org/10.1158/1078-0432.22464380.v1
https://doi.org/10.1158/1078-0432.22464380.v1
Autor:
Richard J. Gilbertson, Karen D. Wright, Christopher Calabrese, Thomas E. Merchant, R. Kipling Guy, Martine F. Roussel, Clinton F. Stewart, Arzu Onar-Thomas, Burgess B. Freeman, Yogesh T. Patel, Amar Gajjar, Hope E. Terhune, Sabrina Terranova, Anang Shelat, Michael DeCuypere, Jason Dapper, Brandon Bianski, Nidal Boulos, Birgit V. Nimmervoll
mouse models of supratentorial ependymoma and CPC and the number of cells implanted as allografts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52ee6974fbde6a9b4e70917a7f447fa7
https://doi.org/10.1158/1078-0432.22464383.v1
https://doi.org/10.1158/1078-0432.22464383.v1
Autor:
Richard J. Gilbertson, Karen D. Wright, Christopher Calabrese, Thomas E. Merchant, R. Kipling Guy, Martine F. Roussel, Clinton F. Stewart, Arzu Onar-Thomas, Burgess B. Freeman, Yogesh T. Patel, Amar Gajjar, Hope E. Terhune, Sabrina Terranova, Anang Shelat, Michael DeCuypere, Jason Dapper, Brandon Bianski, Nidal Boulos, Birgit V. Nimmervoll
Purpose: Curing all children with brain tumors will require an understanding of how each subtype responds to conventional treatments and how best to combine existing and novel therapies. It is extremely challenging to acquire this knowledge in the cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0647a71bda89d85ecc2ab69e89ee1527
https://doi.org/10.1158/1078-0432.c.6525695.v1
https://doi.org/10.1158/1078-0432.c.6525695.v1
Autor:
Lyra Griffiths, Jim Houston, Melissa Johnson, Wayne L. Furman, Anand G. Patel, Walter J. Akers, Rosa Nguyen, Jason Dapper, Michael A. Dyer, Elizabeth Stewart
Publikováno v:
Cancer Immunol Immunother
Faithful tumor mouse models are fundamental research tools to advance the field of immuno-oncology (IO). This is particularly relevant in diseases with low incidence, as in the case of pediatric malignancies, that rely on pre-clinical therapeutic dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::663cca4e03a9d30c36b4a31e946c8f80
https://europepmc.org/articles/PMC8276267/
https://europepmc.org/articles/PMC8276267/
Autor:
Burgess B. Freeman, Jason Dapper, Hope Elizabeth Terhune, Sabrina Terranova, Michael DeCuypere, Anang A. Shelat, Martine F. Roussel, Nidal Boulos, R. Kiplin Guy, Birgit Nimmervoll, Clinton F. Stewart, Thomas E. Merchant, Amar Gajjar, Karen Wright, Christopher Calabrese, Yogesh T. Patel, Richard J. Gilbertson, Arzu Onar-Thomas, Brandon Bianski
Publikováno v:
Clinical Cancer Research. 24:1654-1666
Purpose: Curing all children with brain tumors will require an understanding of how each subtype responds to conventional treatments and how best to combine existing and novel therapies. It is extremely challenging to acquire this knowledge in the cl
Autor:
Cori Bradley, Jason Dapper, Xin Zhou, Jianrong Wu, Armita Bahrami, James R. Downing, Sara M. Federico, Elizabeth Stewart, Asa Karlstrom, Alberto S. Pappo, Nathaniel R. Twarog, Kaley Blankenship, Anang A. Shelat, Jinghui Zhang, Burgess B. Freeman, Victoria Honnell, Richard K. Wilson, Monica Ocarz, John Easton, Beisi Xu, Brittney Gordon, Michael A. Dyer, Xiang Chen, Elaine R. Mardis, Michael R. Clay
Publikováno v:
Nature
Paediatric solid tumours arise from endodermal, ectodermal, or mesodermal lineages. Although the overall survival of children with solid tumours is 75%, that of children with recurrent disease is below 30%. To capture the complexity and diversity of
Autor:
David Finkelstein, Kirti Gupta, Nidal Boulos, Tanya A. Kranenburg, Geoffrey Neale, Elsie White, Scott R. Olsen, Richard J. Gilbertson, Arzu Onar Thomas, Radhika Thiruvenkatam, Christopher J. Eden, Yong-Dong Wang, Jason Dapper, Birgit Nimmervoll, David S. Currle, David W. Ellison, Karen Wright, Kumarasamypet M. Mohankumar, Michele Connelly
Publikováno v:
Nature genetics
Cancers are characterized by non-random chromosome copy number alterations that presumably contain oncogenes and tumor-suppressor genes (TSGs). The affected loci are often large, making it difficult to pinpoint which genes are driving the cancer. Her
Autor:
Yiai Tong, David Finkelstein, Bensheng Ju, Jason Dapper, Richard J. Gilbertson, Nidal Boulos, Michael R. Taylor, Radhika Thiruvenkatam, Christopher J. Eden, Birgit Nimmervoll, Charles A. Lessman, Mohankumar Murugesan, Timothy N. Phoenix, Karen Wright, David W. Ellison
Publikováno v:
Oncogene
High-throughput screens (HTS) of compound toxicity against cancer cells can identify thousands of potential new drug-leads. But only limited numbers of these compounds can progress to expensive and labor intensive efficacy studies in mice, creating a