Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Jason D. Salter"'
Autor:
Ryan P. Bennett, Courtney L. Finch, Elena N. Postnikova, Ryan A. Stewart, Yingyun Cai, Shuiqing Yu, Janie Liang, Julie Dyall, Jason D. Salter, Harold C. Smith, Jens H. Kuhn
Publikováno v:
Viruses, Vol 13, Iss 1, p 52 (2020)
Filoviruses, such as Ebola virus and Marburg virus, are of significant human health concern. From 2013 to 2016, Ebola virus caused 11,323 fatalities in Western Africa. Since 2018, two Ebola virus disease outbreaks in the Democratic Republic of the Co
Externí odkaz:
https://doaj.org/article/5945a79a982544e080a424c8503cb249
Publikováno v:
Sub-cellular biochemistry. 93
The DNA mutagenic enzyme known as APOBEC3G (A3G) plays a critical role in innate immunity to Human Immunodeficiency Virus-1 (HIV-1 ). A3G is a zinc-dependent enzyme that mutates select deoxycytidines (dC) to deoxyuridine (dU) through deamination with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b83d2a250f196268aaa7fe40acdb5595
https://pubmed.ncbi.nlm.nih.gov/31939152
https://pubmed.ncbi.nlm.nih.gov/31939152
Publikováno v:
Trends Mol Med
The infectivity of the human immunodeficiency virus (HIV) depends on overcoming APOBEC3 (A3) innate immunity and does so predominantly through the expression of the viral protein, Vif, which induces A3 degradation in the proteasome. Disruption of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a454076453d4229ba31add94f3654da8
https://doi.org/10.1016/j.molmed.2018.03.004
https://doi.org/10.1016/j.molmed.2018.03.004
Publikováno v:
Subcellular Biochemistry ISBN: 9783030281502
The DNA mutagenic enzyme known as APOBEC3G (A3G) plays a critical role in innate immunity to Human Immunodeficiency Virus-1 (HIV-1 ). A3G is a zinc-dependent enzyme that mutates select deoxycytidines (dC) to deoxyuridine (dU) through deamination with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4b4a2f8162d91161bfb0c41a6911442
https://doi.org/10.1007/978-3-030-28151-9_6
https://doi.org/10.1007/978-3-030-28151-9_6
Autor:
Courtney L. Finch, Shuiqing Yu, Ryan P. Bennett, Janie Liang, Jens H. Kuhn, Elena Postnikova, Julie Dyall, Ryan A. Stewart, Jason D. Salter, Yíngyún Caì, Harold C. Smith
Publikováno v:
Viruses, Vol 13, Iss 52, p 52 (2021)
Viruses
Viruses
Filoviruses, such as Ebola virus and Marburg virus, are of significant human health concern. From 2013 to 2016, Ebola virus caused 11,323 fatalities in Western Africa. Since 2018, two Ebola virus disease outbreaks in the Democratic Republic of the Co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad68ae8367588ec2af7e3fb9d58bdfb6
https://doi.org/10.3390/v13010052
https://doi.org/10.3390/v13010052
Autor:
Jason D, Salter, Harold C, Smith
Publikováno v:
Trends in Biochemical Sciences
The 11-member APOBEC (apolipoprotein B mRNA editing catalytic polypeptide-like) family of zinc-dependent cytidine deaminases bind to RNA and single-stranded DNA (ssDNA) and, in specific contexts, modify select (deoxy)cytidines to (deoxy)uridines. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e5b247644d6e297e225fa5e748863b7
https://pubmed.ncbi.nlm.nih.gov/29803538
https://pubmed.ncbi.nlm.nih.gov/29803538
Autor:
Bradley N. Tun, Michael Cheung, Jason D. Salter, Alan E. Friedman, Bogdan Polevoda, Harold C. Smith, William M. McDougall
Publikováno v:
Nucleic Acids Research
APOBEC3G (A3G) DNA deaminase activity requires a holoenzyme complex whose assembly on nascent viral reverse transcripts initiates with A3G dimers binding to ssDNA followed by formation of higher-order A3G homo oligomers. Catalytic activity is inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f41a1c78215c19cdad30af174e386e2c
https://doi.org/10.1093/nar/gkv970
https://doi.org/10.1093/nar/gkv970
Publikováno v:
Trends in Biochemical Sciences. 39:373-380
HIV-1 viral infectivity factor (Vif) is a viral accessory protein that is required for HIV-1 infection due largely to its role in recruiting antiretroviral factors of the APO-BEC3 (apolipoprotein B editing catalytic subunit-like 3) family to an E3 ub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b8be57ad9e820576710c1268857f266
https://doi.org/10.1016/j.tibs.2014.07.001
https://doi.org/10.1016/j.tibs.2014.07.001
Publikováno v:
Wiley Interdisciplinary Reviews: RNA. 5:493-508
Cytidine deaminases have important roles in the regulation of nucleoside/deoxynucleoside pools for DNA and RNA synthesis. The APOBEC family of cytidine deaminases (named after the first member of the family that was described, Apolipoprotein B mRNA E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ae2d1d906846c0da7b8af0a59b7d7ce
https://doi.org/10.1002/wrna.1226
https://doi.org/10.1002/wrna.1226
Publikováno v:
Trends in biochemical sciences. 41(7)
The APOBEC (apolipoprotein B mRNA editing catalytic polypeptide-like) family of proteins have diverse and important functions in human health and disease. These proteins have an intrinsic ability to bind to both RNA and single-stranded (ss) DNA. Both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e12191481f5ccf6b438e0ceeb228b65
https://pubmed.ncbi.nlm.nih.gov/27283515
https://pubmed.ncbi.nlm.nih.gov/27283515