Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jason D. Foell"'
Autor:
Alexey V. Glukhov, Walatta T. Mesquitta, Jabe M. Best, Kevin P. Vincent, Marites T. Woon, Jason D. Foell, Andrew D. McCulloch, Timothy J. Kamp, Leonid Tyan, Di Lang, Ravi C. Balijepalli, Michael J. Ackerman
Publikováno v:
The Journal of Physiology. 597:1531-1551
Key points Mutations in the caveolae scaffolding protein, caveolin-3 (Cav3), have been linked to the long QT type 9 inherited arrhythmia syndrome (LQT9) and the cause of underlying action potential duration prolongation is incompletely understood. In
Autor:
Leonid, Tyan, Jason D, Foell, Kevin P, Vincent, Marites T, Woon, Walatta T, Mesquitta, Di, Lang, Jabe M, Best, Michael J, Ackerman, Andrew D, McCulloch, Alexey V, Glukhov, Ravi C, Balijepalli, Timothy J, Kamp
Publikováno v:
The Journal of physiology. 597(6)
KEY POINTS: Mutations in the caveolae scaffolding protein, caveolin‐3 (Cav3), have been linked to the long QT type 9 inherited arrhythmia syndrome (LQT9) and the cause of underlying action potential duration prolongation is incompletely understood.
Autor:
Marcin, Kowalski, J Brian, DeVille, J Thomas, Svinarich, Dan, Dan, Andrew, Wickliffe, Charan, Kantipudi, Jason D, Foell, Giovanni, Filardo, Reece, Holbrook, James, Baker, Hassan, Baydoun, Mark, Jenkins, Peter, Chang-Sing
Publikováno v:
The Journal of invasive cardiology. 28(5)
The VALUE PVI study demonstrated that atrial fibrillation (AF) ablation procedures and electrophysiology laboratory (EP lab) occupancy times were reduced for the cryoballoon compared with focal radiofrequency (RF) ablation. However, the economic impa
Autor:
Qinghong Yan, Mi Sun Lee, Timothy J. Kamp, Shian-Ren Liou, Jason D. Foell, Barbara Rosati, Brian Ingalls, David McKinnon
Publikováno v:
The Journal of Physiology. 589:3275-3288
Non-technical summary Appropriate regulation of ion channel expression is critical for the maintenance of both electrical stability and normal contractile function in the heart. A classic way to study the robustness of biological systems is to examin
Autor:
Stacie Kroboth, Yu-Hong Luo, Ravi C. Balijepalli, Nian-Qing Shi, Jason D. Foell, Bin Ye, Qi Ye
Publikováno v:
Biochemistry. 47:12312-12318
Targeting of ion channels to caveolae, a subset of lipid rafts, allow cells to respond efficiently to extracellular signals. Hyperpolarization-activated cyclic nucleotide-gated channel (HCN) 4 is a major subunit for the cardiac pacemaker. Caveolin-3
Autor:
Jessica K. Slind, Sadguna Y. Balijepalli, Jason D. Foell, Brian P. Delisle, Craig T. January, Ravi C. Balijepalli, Timothy J. Kamp
Publikováno v:
Channels. 1:263-272
The localization of ion channels to specific membrane microdomains can impact the functional properties of channels and their role in cellular physiology. We determined the membrane localization of human Kv11.1 (hERG1) alpha-subunit protein, which un
Publikováno v:
Heart rhythm. 13(7)
Background Long-term clinical outcomes for atrial fibrillation ablation depend on the creation of durable transmural lesions during pulmonary vein isolation and on substrate modification. Focal conventional radiofrequency (RF) ablation studies have d
Autor:
Zhaohui Li, Timothy J. Kamp, Matteo Vatta, Enoh E. Ughanze, David J. Tester, Jason D. Foell, Ravi C. Balijepalli, Michael J. Ackerman, Bin Ye, Jonathan C. Makielski, Erica Taylor, Jeffrey A. Towbin
Publikováno v:
Circulation. 114:2104-2112
Background— Congenital long-QT syndrome (LQTS) is a primary arrhythmogenic syndrome stemming from perturbed cardiac repolarization. LQTS, which affects ≈1 in 3000 persons, is 1 of the most common causes of autopsy-negative sudden death in the you
Publikováno v:
Proceedings of the National Academy of Sciences. 103:7500-7505
L-type Ca 2+ channels play a critical role in regulating Ca 2+ -dependent signaling in cardiac myocytes, including excitation-contraction coupling; however, the subcellular localization of cardiac L-type Ca 2+ channels and their regulation are incomp
Autor:
Timothy J. Kamp, Johannes W. Hell, Ravi C. Balijepalli, Jason D. Foell, Vaibhavi Shah, Risa M. Cohen
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 288:H2363-H2374
Recent studies have identified a growing diversity of splice variants of auxiliary Ca2+channel Cavβ subunits. The Cavβ1disoform encodes a putative protein composed of the amino-terminal half of the full-length Cavβ1isoform and thus lacks the known