Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jason D. Downey"'
Autor:
Craig W. Lindsley, Richard M. Breyer, Jason D. Downey, Sarah E. Davis, Ryan P. Ceddia, Maria P. Kraemer, Jing Wu, J. Scott Daniels, Ryan D. Morrison, Huiyong Yin
Publikováno v:
Prostaglandins Other Lipid Mediat
Background/aims The prostaglandin E2 (PGE2) EP3 receptor has a multifaceted role in metabolism. Drugs targeting EP3 have been proposed as therapeutics for diabetes; however, studies utilizing global EP3 knockout mice suggest that EP3 blockade increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2995492bcaf2bd035f7632e2361c1fdf
https://pubmed.ncbi.nlm.nih.gov/31276827
https://pubmed.ncbi.nlm.nih.gov/31276827
Autor:
Lamont Booker, Diane M Hildenberger, Susan M. DeLeon, Melissa O Rhoomes, Gary A. Rockwood, Jason D. Downey, Kelly A. Basi
Publikováno v:
Clinical toxicology (Philadelphia, Pa.). 56(5)
Cyanide (CN) is a metabolic poison, halting ATP synthesis by inhibiting complex IV of the electron transport chain. If exposed at high enough concentrations, humans and most animals can die within minutes. Because time is a crucial factor in survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36bcd8396dabceccb54ac9914462900e
https://pubmed.ncbi.nlm.nih.gov/30449190
https://pubmed.ncbi.nlm.nih.gov/30449190
Publikováno v:
Toxicology of Cyanides and Cyanogens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5debf72b56be8598e0b8e72a32560a5e
https://doi.org/10.1002/9781118628966.ch2
https://doi.org/10.1002/9781118628966.ch2
Publikováno v:
Prostaglandinsother lipid mediators. 94(1-2)
To determine the contribution of cysteines to the function of the mouse E-prostanoid subtype 3 gamma (mEP3γ), we tested a series of cysteine-to-alanine mutants. Two of these mutants, C107A and C184A, showed no agonist-dependent activation in a cell-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::109370b9062b1176e1dd535b331ac908
https://pubmed.ncbi.nlm.nih.gov/21236356
https://pubmed.ncbi.nlm.nih.gov/21236356
Autor:
Sam Saleh, Thomas M. Bridges, Ryan D. Morrison, Jason D. Downey, Craig W. Lindsley, Richard M. Breyer, J. Scott Daniels
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:6939
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9160d883f8f56117a9882cc51d6f4719
https://doi.org/10.1016/j.bmcl.2013.10.023
https://doi.org/10.1016/j.bmcl.2013.10.023