Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Jason Cham"'
Autor:
Aren Ebrahimi, Jason Cham, Leah Puglisi, Melanie De Shadarevian, David J. Hermel, Samantha R. Spierling Bagsic, Darren Sigal
Publikováno v:
Cancer Medicine, Vol 12, Iss 9, Pp 10243-10253 (2023)
Abstract Introduction Pancreatic ductal adenocarcinoma (PDAC) is a genetically heterogeneous disease often diagnosed with synchronous metastatic disease involving the liver. Tumors with extra‐abdominal spread that bypass the liver are thought to re
Externí odkaz:
https://doaj.org/article/41bb68d17109444c9a773034bd96bf7a
Autor:
Ki Suk Eum, Allison Martin, Michael Quigley, Jason Cham, Jacob New, Lana Smith, Leah Puglisi, Tridu Huynh, Sunil Kurian, Samantha Bagsic, Russel Fielding, Lee Hong, Priya Reddy, Bethany Barrick, Christopher Marsh, Laura J Nicholson, Amitabh C Pandey
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 1 (2024)
Background Despite immunization, patients on antineoplastic and immunomodulating agents have a heightened risk of COVID-19 infection. However, accurately attributing this risk to specific medications remains challenging.Methods An observational cohor
Externí odkaz:
https://doaj.org/article/6800c4872a484638acb744d6c47e4f50
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
T cells represent a crucial component of the adaptive immune system and mediate anti-tumoral immunity as well as protection against infections, including respiratory viruses such as SARS-CoV-2. Next-generation sequencing of the T-cell receptors (TCRs
Externí odkaz:
https://doaj.org/article/91da49dec5e240a7a4a633e0561501d1
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Prostate cancer is the most common cancer in men. About 6% of those diagnosed will develop metastatic disease. Unfortunately, metastatic prostate cancer is fatal. Prostate cancer can be castration sensitive or castration resistant. Many treatments ha
Externí odkaz:
https://doaj.org/article/780d16ecaf164dd084f8084ad4340331
Publikováno v:
Journal of Medical Case Reports, Vol 15, Iss 1, Pp 1-4 (2021)
Abstract Background Immune checkpoint inhibitors are effective therapies for a wide range of malignancies. Their increased use has led to a wide range of immune-related adverse effects including skin, gastrointestinal, pulmonary, endocrine, cardiac,
Externí odkaz:
https://doaj.org/article/024d955d2197463fad35d841d99ca303
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
The T and B cell repertoire make up the adaptive immune system and is mainly generated through somatic V(D)J gene recombination. Thus, the VJ gene usage may be a potential prognostic or predictive biomarker. However, analysis of the adaptive immune s
Externí odkaz:
https://doaj.org/article/539f3f0210f2460aa0d1a105f7f9deb2
Autor:
Sara Tamizuddin, Jason Cham, Yasamin Ghiasi, Luis Borroto, Cindy Cao, Natalia Orendain, Michael M Quigley, Laura J Nicholson, Amitabh C Pandey
Publikováno v:
Future Science OA, Vol 8, Iss 3 (2022)
Aim: This study investigated the humoral response against SARS-CoV-2 in patients needing intensive care unit (ICU) care compared with those on general medicine wards. Materials & methods: The authors retrospectively reviewed 113 hospitalized patients
Externí odkaz:
https://doaj.org/article/e1358cb5bdfc433782b62388edd0cb12
Autor:
Jason Cham, Amitabh C. Pandey, Jacob New, Tridu Huynh, Lee Hong, Natalia Orendain, Eric J. Topol, Laura J. Nicholson
Publikováno v:
PLoS ONE, Vol 17, Iss 4 (2022)
Aim Healthcare workers (HCWs) were among the first group of people vaccinated with the Pfizer-BioNTech Covid-19 vaccine (BNT162b2). Characterization of the kinetics of antibody response to vaccination is important to devise future vaccination strateg
Externí odkaz:
https://doaj.org/article/1bc7758698494586b59481de5e7b4796
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundMelanoma has a wide range of histologic variants and cytomorphologic features that make its diagnosis challenging. Melanoma can also rarely have neuroendocrine markers adding further diagnostic uncertainty particularly given that unrelated
Externí odkaz:
https://doaj.org/article/5df484e4c2ba4f82b8daef6c02eb2f9d
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background CTLA-4 blockade with ipilimumab is Food and Drug Administration-approved for melanoma as a monotherapy and has been shown to modulate the circulating T-cell repertoire. We have previously reported clinical trials combining CTLA-4 blockade
Externí odkaz:
https://doaj.org/article/e9b04a978bf84e95ba7473a37206827c