Výsledky vyhledávání - "Jason C. Zabeli"

Akademický článek

Molecular and Biological Characterization of a New Isolate of Guinea Pig Cytomegalovirus

Autor: Mark R. Schleiss, Shane McAllister, Anibal G. Armién, Nelmary Hernandez-Alvarado, Claudia Fernández-Alarcón, Jason C. Zabeli, Thiruvarangan Ramaraj, John A. Crow, Michael A. McVoy

Publikováno v: Viruses, Vol 6, Iss 2, Pp 448-475 (2014)

Development of a vaccine against congenital infection with human cytomegalovirus is complicated by the issue of re-infection, with subsequent vertical transmission, in women with pre-conception immunity to the virus. The study of experimental therape

Externí odkaz: https://doaj.org/article/257a55617d6444ce8493ca4a354c65be

Zobrazit plný text záznamu

Comparison of monovalent glycoprotein B with bivalent gB/pp65 (GP83) vaccine for congenital cytomegalovirus infection in a guinea pig model: Inclusion of GP83 reduces gB antibody response but both vaccine approaches provide equivalent protection against pup mortality

Autor: Pete Gillis, Felix Wussow, Claudia Fernández-Alarcón, Jason C. Zabeli, Don J. Diamond, Elizabeth C. Swanson, Megan Schmit, Mark R. Schleiss, Nelmary Hernandez-Alvarado

Publikováno v: Vaccine. 33:4013-4018

Cytomegalovirus (CMV) subunit vaccine candidates include glycoprotein B (gB), and phosphoprotein ppUL83 (pp65). Using a guinea pig cytomegalovirus (GPCMV) model, this study compared immunogenicity, pregnancy outcome, and congenital viral infection fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dad6072680da22e259b92f42e99dd350
https://doi.org/10.1016/j.vaccine.2015.06.019

Zobrazit plný text záznamu

Assessing Zika virus replication and the development of Zika-specific antibodies after a mid-gestation viral challenge in guinea pigs

Autor: Dira S. Putri, Nelmary Hernandez-Alvarado, Bradley C. Janus, Craig J. Bierle, Claudia Fernández-Alarcón, Jason C. Zabeli, Mark R. Schleiss

Publikováno v: PLoS ONE
PLoS ONE, Vol 12, Iss 11, p e0187720 (2017)

Primary Zika virus (ZIKV) infections that occur during pregnancy can cause spontaneous abortion and profoundly disrupt fetal development. While the full range of developmental abnormalities associated with congenital Zika syndrome is not yet known, s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16e6327a220062db6520664c94fe9386
https://pubmed.ncbi.nlm.nih.gov/29099873

Zobrazit plný text záznamu

Additive Protection against Congenital Cytomegalovirus Conferred by Combined Glycoprotein B/pp65 Vaccination Using a Lymphocytic Choriomeningitis Virus Vector

Autor: Ursula Berka, Thomas P. Monath, Mark R. Schleiss, Claudia Fernández-Alarcón, Michael G. Schwendinger, Jason C. Zabeli, Peter A. Gillis, Mario Aistleithner, Anders Lilja, Elizabeth C. Swanson, Farshad Guirakhoo, Bastien Mangeat, Daniel D. Pinschewer, Elizabeth M. Watson, Bettina Kiefmann, Klaus Orlinger, Nelmary Hernandez-Alvarado

Publikováno v: Clinical and Vaccine Immunology. 24

Subunit vaccines for prevention of congenital cytomegalovirus (CMV) infection based on glycoprotein B (gB) and pp65 are in clinical trials, but it is unclear whether simultaneous vaccination with both antigens enhances protection. We undertook evalua

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2611f54e93c5eb579454e1c39d38c18
https://doi.org/10.1128/cvi.00300-16

Zobrazit plný text záznamu

Molecular and Biological Characterization of a New Isolate of Guinea Pig Cytomegalovirus

Autor: Thiruvarangan Ramaraj, Michael A. McVoy, John A. Crow, Claudia Fernández-Alarcón, Nelmary Hernandez-Alvarado, Jason C. Zabeli, Shane C McAllister, Aníbal G. Armién, Mark R. Schleiss

Publikováno v: Viruses
Viruses, Vol 6, Iss 2, Pp 448-475 (2014)
Volume 6
Issue 2
Pages 448-475

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee610ab316062cb3bfe5a9993a597a9
http://europepmc.org/articles/PMC3939465

Zobrazit plný text záznamu

Repair of a Mutation Disrupting the Guinea Pig Cytomegalovirus Pentameric Complex Acquired during Fibroblast Passage Restores Pathogenesis in Immune-Suppressed Guinea Pigs and in the Context of Congenital Infection

Autor: Claudia Fernández-Alarcón, Jason C. Zabeli, Craig J. Bierle, Elizabeth C. Swanson, Nelmary Hernandez-Alvarado, Dirk P. Dittmer, Mark R. Schleiss, Michael A. McVoy, Jian Ben Wang

Guinea pig cytomegalovirus (GPCMV) provides a valuable model for congenital cytomegalovirus transmission. Salivary gland (SG)-passaged stocks of GPCMV are pathogenic, while tissue culture (TC) passage in fibroblasts results in attenuation. Nonpathoge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0715ca4703d230b79362677173d0dc5

Zobrazit plný text záznamu

Akademický článek

Assessing Zika virus replication and the development of Zika-specific antibodies after a mid-gestation viral challenge in guinea pigs.

Autor: Craig J Bierle, Claudia Fernández-Alarcón, Nelmary Hernandez-Alvarado, Jason C Zabeli, Bradley C Janus, Dira S Putri, Mark R Schleiss

Publikováno v: PLoS ONE, Vol 12, Iss 11, p e0187720 (2017)

Externí odkaz: https://doaj.org/article/6d3545367ad843f6805b2b84317de7fe

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání