Výsledky vyhledávání - "Jason C. Reneau"

Cerebellar granule cells cultured from adolescent rats express functional NMDA receptors: anin vitromodel for studying the developing cerebellum

Autor: Jason C. Reneau, R. Lisa Popp, Janet Dertien

Publikováno v: Journal of Neurochemistry. 106:900-911

In the developing rat cerebellum functional NMDA receptors (NMDARs) expressing the NR2C subunit have been identified on or after postnatal day 19. We obtained primary cultured cells from 19- to 35-day-old rat cerebellum that expressed few oligodendro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::31c0a6950982dfe2eeaf7e1cf61826dd
https://doi.org/10.1111/j.1471-4159.2008.05464.x

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Acute ethanol exposure prevents PMA-mediated augmentation of N-methyl-D-aspartate receptor function in primary cultured cerebellar granule cells

Autor: Jason C. Reneau, Mary E. Reyland, R. Lisa Popp

Publikováno v: Alcohol (Fayetteville, N.Y.). 45(6)

Many intracellular proteins and signaling cascades contribute to the ethanol sensitivity of native N-methyl-D-aspartate receptors (NMDARs). One putative protein is the serine/threonine kinase, protein kinase C (PKC). The purpose of this study was to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4a5c93ae95ab4205f28a20e35c8545c
https://pubmed.ncbi.nlm.nih.gov/21624785

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An in vitro model for studying the effects of continuous ethanol exposure on N-methyl-D-aspartate receptor function

Autor: Kafayat Busari, Ian Guerra, Jason C. Reneau, Mary Kate Neumann, Vikas Nath, Yaminiben I. Bhakta, Susan E. Bergeson, Rajiv G. Agrawal, Janet Dertien, R. Lisa Popp

Publikováno v: Alcohol (Fayetteville, N.Y.). 46(1)

Long-term ethanol exposure has deleterious effects on both glial and neuronal function. We assessed alterations in both astrocytic and neuronal viability, as well as alterations in N-methyl-d-aspartate receptor (NMDAR) function, in co-cultures of rat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b996c1cf4286a8289eb67490cfa6f77
https://pubmed.ncbi.nlm.nih.gov/21925827

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Phorbol 12-Myristate 13-Acetate Potentiation of N-Methyl-d-aspartate-Induced Currents in Primary Cultured Cerebellar Granule Cells Is Mediated by Protein Kinase Cα

Autor: Mary E. Reyland, R. Lisa Popp, Jason C. Reneau, Jonathan E. Phillips, Carissa Kindy

We have previously reported that activation of protein kinase C (PKC) by phorbol 12-myristate 13-acetate (PMA) results in potentiation of N-methyl-D-aspartate-induced currents (I(NMDA))of receptors contained in primary cultured cerebellar granule cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6646b05a35ec8dd83cca24e1d98e53fd
https://europepmc.org/articles/PMC2713095/

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Activation of protein kinase C enhances NMDA-induced currents in primary cultured cerebellar granule cells: Effect of temperature and NMDA NR2 subunit composition

Autor: R. Lisa Popp, Jason C. Reneau, B. Jason Brotherton

Publikováno v: European journal of pharmacology. 599(1-3)

The purpose of this study was to determine the effect of protein kinase C (PKC) activation by 100 nM phorbol 12-myristate 13-acetate (PMA) on N-methyl-d-aspartate (NMDA) receptor function with the whole-cell patch-clamp technique. Receptors expressed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88aa6ff09db507373f31b7b4bd51ed14
https://pubmed.ncbi.nlm.nih.gov/18762183

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