Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jason C. McCoy"'
Publikováno v:
Biochem J
Growth differentiation factor 8 (GDF8), a.k.a. myostatin, is a member of the larger TGFβ superfamily of signaling ligands. GDF8 has been well characterized as a negative regulator of muscle mass. After synthesis, GDF8 is held latent by a noncovalent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d13faeaadb7591897fd192b4ef7263a
https://doi.org/10.1042/bcj20210054
https://doi.org/10.1042/bcj20210054
Publikováno v:
Journal of Biological Chemistry. 294:6333-6343
Growth differentiation factor 8 (GDF8; also known as myostatin) and GDF11 are closely related members of the transforming growth factor β (TGF-β) family. GDF8 strongly and negatively regulates skeletal muscle growth, and GDF11 has been implicated i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3025e78b1e13de68719dd655720c15e6
https://doi.org/10.1074/jbc.ra118.005831
https://doi.org/10.1074/jbc.ra118.005831
Autor:
Magdalena Czepnik, Jason C. McCoy, Erich J Goebel, Kelly L. Walton, Miook Cho, Craig A. Harrison, Gauthier Schang, Amy J. Wagers, Erik Martinez-Hackert, Ryan G. Walker, Daniel J. Bernard, Andrew P. Hinck, Senem Aykul, Juhyun Oh, Thomas B. Thompson, Ana Vujic, Richard T. Lee
Publikováno v:
BMC Biology
Background Growth/differentiation factor 8 (GDF8) and GDF11 are two highly similar members of the transforming growth factor β (TGFβ) family. While GDF8 has been recognized as a negative regulator of muscle growth and differentiation, there are con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1297a842fc51892500d150836c2c8b13
Autor:
Jason C. McCoy, Gregory Royce Gipson, Emily C. Kappes, Kaitlin N. Hart, Thomas B. Thompson, Erich J Goebel, Chandramohan Kattamuri
Publikováno v:
Bone
The Bone Morphogenetic Proteins (BMPs) are the largest class signaling molecules within the greater Transforming Growth Factor Beta (TGFβ) family, and are responsible for a wide array of biological functions, including dorsal-ventral patterning, ske
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf84d70cbcf445f48544a5d3fd1d8557
https://europepmc.org/articles/PMC7502536/
https://europepmc.org/articles/PMC7502536/
Publikováno v:
Exp Biol Med (Maywood)
The transforming growth factor beta (TGFβ) signaling pathway orchestrates a wide breadth of biological processes, ranging from bone development to reproduction. Given this, there has been a surge of interest from the drug development industry to mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::341a8d84698a51ab7e7f4229763aee87
https://pubmed.ncbi.nlm.nih.gov/31594405
https://pubmed.ncbi.nlm.nih.gov/31594405
Autor:
Timothy C. Cox, Andrew C. Lidral, Jason C. McCoy, Huan Liu, Liza L. Cox, Ying Zhu, Ryan D. Anderson, Lina M. Moreno Uribe, Deepti Anand, Mei Deng, Chika T. Richter, Nichole L. Nidey, Jennifer M. Standley, Elizabeth E. Blue, Jessica X. Chong, Joshua D. Smith, Edwin P. Kirk, Hanka Venselaar, Katy N. Krahn, Hans Bokhoven, Huiqing Zhou, Robert A. Cornell, Ian A. Glass, Michael J. Bamshad, Deborah A. Nickerson, Jeffrey C. Murray, Salil A. Lachke, Thomas B. Thompson, Michael F. Buckley, Tony Roscioli
Publikováno v:
Human Mutation. 40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::496605ae1187a52a5d5c62072a5e6074
https://doi.org/10.1002/humu.23923
https://doi.org/10.1002/humu.23923
Autor:
Jason C. McCoy, Thomas B. Thompson
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::282fe4779b67bbb3e105dcd6fa6a7e64
https://doi.org/10.1096/fasebj.2019.33.1_supplement.461.14
https://doi.org/10.1096/fasebj.2019.33.1_supplement.461.14
Publikováno v:
Journal of Virology. 90:9582-9597
Two types of viruses are produced during the baculovirus life cycle: budded virus (BV) and occlusion-derived virus (ODV). A particular baculovirus protein, FP25K, is involved in the switch from BV to ODV production. Previously, FP25K from the model a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eb782521e93fdb7f0dcabb8345dc7e6
https://doi.org/10.1128/jvi.01241-16
https://doi.org/10.1128/jvi.01241-16
Autor:
Andrew C. Lidral, Deborah A. Nickerson, Ryan D. Anderson, Chika T. Richter, Robert A. Cornell, Lina M. Moreno Uribe, Huiqing Zhou, Deepti Anand, Jessica X. Chong, Hans van Bokhoven, Elizabeth E. Blue, Edwin P. Kirk, Mei Deng, Joshua D. Smith, Nichole Nidey, Jason C. McCoy, Jennifer Standley, Huan Liu, Katy N. Krahn, Jeffrey C. Murray, Salil A. Lachke, Hanka Venselaar, Timothy C. Cox, Michael J. Bamshad, Tony Roscioli, Ying Zhu, Michael F. Buckley, Ian A. Glass, Liza L Cox, Thomas B. Thompson
Publikováno v:
Hum Mutat
Human Mutation, 40, 10, pp. 1813-1825
Human Mutation, 40, 1813-1825
Human Mutation, 40, 10, pp. 1813-1825
Human Mutation, 40, 1813-1825
Contains fulltext : 208676.pdf (Publisher’s version ) (Open Access) Cleft lip with or without cleft palate (CL/P) is generally viewed as a complex trait with multiple genetic and environmental contributions. In 70% of cases, CL/P presents as an iso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8a989194cf576016e2505f9cf67f020
https://pubmed.ncbi.nlm.nih.gov/31215115
https://pubmed.ncbi.nlm.nih.gov/31215115
Autor:
Madgalena Czepnik, Marko Hyvönen, Jason C. McCoy, Xuelu Wang, Thomas R. Cotton, Thomas B. Thompson, Gerhard Fischer
Myostatin, a key regulator of muscle mass in vertebrates, is biosynthesised as a latent precursor in muscle and is activated by sequential proteolysis of the pro-domain. To investigate the molecular mechanism by which pro-myostatin remains latent, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e16cf25bfd882626efad1b91fbfc266
https://www.repository.cam.ac.uk/handle/1810/273563
https://www.repository.cam.ac.uk/handle/1810/273563