Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jason C. Maynard"'
Autor:
Swetha Mohan, Paul J. Sampognaro, Andrea R. Argouarch, Jason C. Maynard, Mackenzie Welch, Anand Patwardhan, Emma C. Courtney, Jiasheng Zhang, Amanda Mason, Kathy H. Li, Eric J. Huang, William W. Seeley, Bruce L. Miller, Alma Burlingame, Mathew P. Jacobson, Aimee W. Kao
Publikováno v:
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-18 (2021)
Abstract Background Progranulin loss-of-function mutations are linked to frontotemporal lobar degeneration with TDP-43 positive inclusions (FTLD-TDP-Pgrn). Progranulin (PGRN) is an intracellular and secreted pro-protein that is proteolytically cleave
Externí odkaz:
https://doaj.org/article/2bcbf5d1642d41eea3c3e628a2a7b9be
Autor:
Bing Liu, Oscar C. Salgado, Sangya Singh, Keli L. Hippen, Jason C. Maynard, Alma L. Burlingame, Lauren E. Ball, Bruce R. Blazar, Michael A. Farrar, Kristin A. Hogquist, Hai-Bin Ruan
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
The transcription factor Foxp3 and Stat5 modulate lineage stability and function of regulatory T (Treg) cells to promote immune homeostasis. Here the authors show that O-GlcNAcylation of Foxp3 and Stat5, mediated by O-GlcNAc transferase (OGT), is ess
Externí odkaz:
https://doaj.org/article/753e12c8c75848d7bf15336570926002
Autor:
Zengdi Zhang, Zan Huang, Mohamed Awad, Mohammed Elsalanty, James Cray, Lauren E Ball, Jason C Maynard, Alma L Burlingame, Hu Zeng, Kim C Mansky, Hai-Bin Ruan
Publikováno v:
eLife, Vol 12 (2023)
In mammals, interactions between the bone marrow (BM) stroma and hematopoietic progenitors contribute to bone-BM homeostasis. Perinatal bone growth and ossification provide a microenvironment for the transition to definitive hematopoiesis; however, m
Externí odkaz:
https://doaj.org/article/9f3565164f5a4c418d666d711bac7fd1
Autor:
Yang Bi, Ruben Shrestha, Zhenzhen Zhang, Chuan-Chih Hsu, Andres V Reyes, Sumudu Karunadasa, Peter R Baker, Jason C Maynard, Yang Liu, Amirmansoor Hakimi, Daniel Lopez-Ferrer, Tahmid Hassan, Robert J Chalkley, Shou-Ling Xu, Zhi-Yong Wang
Publikováno v:
The Plant Cell. 35:1318-1333
The recent discovery of SPINDLY (SPY)-catalyzed protein O-fucosylation revealed a novel mechanism for regulating nucleocytoplasmic protein functions in plants. Genetic evidence indicates the important roles of SPY in diverse developmental and physiol
Autor:
Zan Huang, Zengdi Zhang, Mohamed Awad, Mohammed Elsalanty, James Cray, Lauren E Ball, Jason C Maynard, Alma L Burlingame, Hu Zeng, Kim C Mansky, Hai-Bin Ruan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7225d2e6e510930c4576b58180ad4d4
https://doi.org/10.7554/elife.85464.sa2
https://doi.org/10.7554/elife.85464.sa2
Autor:
Zengdi Zhang, Zan Huang, Mohamed Awad, Mohammed Elsalanty, James Cray, Lauren E. Ball, Jason C. Maynard, Alma L. Burlingame, Hu Zeng, Kim C. Mansky, Hai-Bin Ruan
SUMMARYIn mammals, interactions between the bone marrow (BM) stroma and hematopoietic progenitors contribute to bone-BM homeostasis. Perinatal bone growth and ossification provide a microenvironment for the transition to definitive hematopoiesis; how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c8e0691b3dc4d78b24cf741ef5cc74d
https://doi.org/10.1101/2022.12.21.521379
https://doi.org/10.1101/2022.12.21.521379
Autor:
Saul A. Villeda, Jason C. Maynard, Xuelai Fan, Elizabeth G. Wheatley, Gregor Bieri, Charles W. White, Alma L. Burlingame, Julien Couthouis
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Depletion of the neural stem cell (NSC) pool is a major driver of age-related regenerative decline in the hippocampus. While increased quiescence is a major contributor to this decline, NSCs can also undergo terminal differentiation into
Autor:
Ming Zhao, Kaiqun Ren, Xiwen Xiong, Yue Xin, Yujie Zou, Jason C. Maynard, Angela Kim, Alexander P. Battist, Navya Koneripalli, Yusu Wang, Qianyue Chen, Ruyue Xin, Chenyan Yang, Rong Huang, Jiahui Yu, Zan Huang, Zengdi Zhang, Haiguang Wang, Daoyuan Wang, Yihui Xiao, Oscar C. Salgado, Nicholas N. Jarjour, Kristin A. Hogquist, Xavier S. Revelo, Alma L. Burlingame, Xiang Gao, Jakob von Moltke, Zhaoyu Lin, Hai-Bin Ruan
Publikováno v:
Immunity
The epithelium is an integral component of mucosal barrier and host immunity. Following helminth infection, the intestinal epithelial cells secrete "alarmin" cytokines, such as interleukin-25 (IL-25) and IL-33, to initiate the type 2 immune responses
Autor:
Joel Hrit, Alma L. Burlingame, Barbara Panning, Augspurger K, Steve E. Jacobsen, Suhua Feng, Jason C. Maynard, Colette L. Picard, Elizabeth Allene Martin
Author(s): Martin, Elizabeth Allene | Advisor(s): Panning, Barbara | Abstract: Female (XX) mouse embryonic stem cells (mESCs) differ from their male (XY) counterparts because they have lower levels of 5-methylcytosine (5mC) and 5-hydroxymethylcytosin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a96022dac8b2f9b97207d13f2e612c95
https://doi.org/10.1101/2021.06.19.449113
https://doi.org/10.1101/2021.06.19.449113
Autor:
Robert J. Chalkley, Jason C. Maynard
Publikováno v:
Molecular & Cellular Proteomics : MCP
O-GlcNAcylation, the addition of a single N-acetylglucosamine residue to serine and threonine residues of cytoplasmic, nuclear, or mitochondrial proteins, is a widespread regulatory posttranslational modification. It is involved in the response to nu