Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Jason C. Harper"'
Publikováno v:
Drug Delivery, Vol 25, Iss 1, Pp 1234-1257 (2018)
Gene therapy has long held promise to correct a variety of human diseases and defects. Discovery of the Clustered Regularly-Interspaced Short Palindromic Repeats (CRISPR), the mechanism of the CRISPR-based prokaryotic adaptive immune system (CRISPR-a
Externí odkaz:
https://doaj.org/article/b314c626f737436fbb97e72220010ecc
Publikováno v:
Metabolites, Vol 7, Iss 3, p 39 (2017)
Fragrances and malodors are ubiquitous in the environment, arising from natural and artificial processes, by the generation of volatile organic compounds (VOCs). Although VOCs constitute only a fraction of the metabolites produced by an organism, the
Externí odkaz:
https://doaj.org/article/9892bb031605400693973dd084d270bb
Publikováno v:
Drug Delivery
Drug Delivery, Vol 25, Iss 1, Pp 1234-1257 (2018)
Drug Delivery, Vol 25, Iss 1, Pp 1234-1257 (2018)
Gene therapy has long held promise to correct a variety of human diseases and defects. Discovery of the Clustered Regularly-Interspaced Short Palindromic Repeats (CRISPR), the mechanism of the CRISPR-based prokaryotic adaptive immune system (CRISPR-a
Publikováno v:
ACS Biomaterials Science & Engineering. 3:2098-2109
Over the last twenty years, many strategies utilizing sol-gel chemistry to integrate biological cells into silica-based materials have been reported. One such strategy, Sol-Generating Chemical Vapor into Liquid (SG-CViL) deposition, shows promise as
Autor:
Jason C. Harper, Eric Jakobsson, Jennifer Pelowitz, C. Jeffrey Brinker, Patrick E. Johnson, Zeeshan Fazal
Publikováno v:
ACS Nano. 11:3560-3575
In order to design hybrid cellular/synthetic devices such as sensors and vaccines, it is important to understand how the metabolic state of living cells changes upon physical confinement within three-dimensional (3D) matrices. We analyze the gene exp
Autor:
Jason C. Harper, Edwin A. Saada, Joshua D. Podlevsky, Steven S. Branda, Robert K. Johnston, Jerilyn A. Timlin, Kyle J. Seamon
Publikováno v:
Biosensorsbioelectronics. 141
The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) ribonucleoprotein (RNP) complex is an RNA-guided DNA-nuclease that is part of the bacterial adaptive immune system. CRISPR/Cas9 RNP has been ada
Autor:
Jason C. Harper, William G. Yelton
This article discusses the fundamentals of electroplating processes, including pre-electroplating and surface-preparation processes. It illustrates the four layers of a plating system, namely, top or finish coat, undercoat, strike or flash, and base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e70a18f2fed87c12efea5a346119b49
https://doi.org/10.31399/asm.hb.v18.a0006395
https://doi.org/10.31399/asm.hb.v18.a0006395
Autor:
Darren R. Dunphy, Travis Savage, Svetlana Harbaugh, Jason C. Harper, Nancy Kelley-Loughnane, C. Jeffrey Brinker
Publikováno v:
ACS Biomaterials Science & Engineering. 1:1231-1238
The remarkable impact encapsulation matrix chemistry can have on the bioactivity and viability of integrated living cells is reported. Two silica chemistries (aqueous silicate and alkoxysilane), and a functional component additive (glycerol), are emp
Autor:
Jason C. Harper, William Arndt, Melissa Finley, Thayne L. Edwards, C. Jeffrey Brinker, Bryan Carson, George D. Bachand
Publikováno v:
Electroanalysis. 27:2503-2512
D espite significant progress in development of bioanalytical devices cost, complexity ,a ccess to reagents and lack of infrastructure have prevented use of these technologies in resource-limited regions .T op rovide as us- tainable tool in the globa
Publikováno v:
Journal of Materials Chemistry B. 3:1032-1041
In nature, cells perform a variety of complex functions such as sensing, catalysis, and energy conversion which hold great potential for biotechnological device construction. However, cellular sensitivity to ex vivo environments necessitates developm