Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jason C. Gardner"'
Autor:
Yasuaki Uehara, Yusuke Tanaka, Shuyang Zhao, Nikolaos M. Nikolaidis, Lori B. Pitstick, Huixing Wu, Jane J. Yu, Erik Zhang, Yoshihiro Hasegawa, John G. Noel, Jason C. Gardner, Elizabeth J. Kopras, Wendy D. Haffey, Kenneth D. Greis, Jinbang Guo, Jason C. Woods, Kathryn A. Wikenheiser-Brokamp, Jennifer E. Kyle, Charles Ansong, Steven L. Teitelbaum, Yoshikazu Inoue, Göksel Altinişik, Yan Xu, Francis X. McCormack
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Osteoclasts are derived from circulating myeloid cells to mediate bone repair, maintenance and remodeling. Here, the authors show that the lung also recruits and reprograms monocytes and alveolar macrophages into osteoclast-like cells to clear pathog
Externí odkaz:
https://doaj.org/article/31bc357b81304579bc6ef7c4759424c7
Autor:
John G. Noel, Seth W. Ramser, Lori Pitstick, John P. Bonamer, Bryan Mackenzie, Katie G. Seu, Theodosia A. Kalfa, Jose A. Cancelas, Jason C. Gardner
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract M-CSF receptor signaling supports the development and survival of mononuclear phagocytes and is thought to play a role in post burn anemia by promoting myeloid lineage bias. We found M-CSF secretion was increased in burn patients and a murin
Externí odkaz:
https://doaj.org/article/574ad174994b4b668e96e765e451a0b2
Autor:
Debabrata Chowdhury, Jason C. Gardner, Abhijit Satpati, Suba Nookala, Santhosh Mukundan, Aleksey Porollo, Julio A. Landero Figueroa, Kavitha Subramanian Vignesh
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Non-canonical inflammasome activation by mouse caspase-11 (or human CASPASE-4/5) is crucial for the clearance of certain gram-negative bacterial infections, but can lead to severe inflammatory damage. Factors that promote non-canonical inflammasome a
Externí odkaz:
https://doaj.org/article/86619dadcfc5411caafc7903c65e9794
Autor:
John G. Noel, Seth W. Ramser, Lori Pitstick, Holly S. Goetzman, Elizabeth L. Dale, Andrew Potter, Mike Adam, S. Steven Potter, Jason C. Gardner
Publikováno v:
The Journal of Immunology. 210:972-980
The anemia of critical illness (ACI) is a nearly universal pathophysiological consequence of burn injury and a primary reason burn patients require massive quantities of transfused blood. Inflammatory processes are expected to drive postburn ACI and
Autor:
Yoshihiro Hasegawa, Jennifer M. Franks, Yusuke Tanaka, Yasuaki Uehara, David F. Read, Claire Williams, Sanjay Srivatsan, Lori B. Pitstick, Nikolaos M. Nikolaidis, Ciara M. Shaver, Huixing Wu, Jason C. Gardner, Andrew R. Osterburg, Jane J. Yu, Elizabeth J. Kopras, Steven L. Teitelbaum, Kathryn A. Wikenheiser-Brokamp, Cole Trapnell, Francis X. McCormack
Publikováno v:
bioRxiv
The pathophysiology of silicosis is poorly understood, limiting development of therapies for those who have been exposed to the respirable particle. We explored the mechanisms of silica-induced pulmonary fibrosis in a mouse model using multiple modal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::252473b494e60975229929dfaecbbcbc
https://europepmc.org/articles/PMC9949165/
https://europepmc.org/articles/PMC9949165/