Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Jason C. Harper"'
Publikováno v:
Drug Delivery, Vol 25, Iss 1, Pp 1234-1257 (2018)
Gene therapy has long held promise to correct a variety of human diseases and defects. Discovery of the Clustered Regularly-Interspaced Short Palindromic Repeats (CRISPR), the mechanism of the CRISPR-based prokaryotic adaptive immune system (CRISPR-a
Externí odkaz:
https://doaj.org/article/b314c626f737436fbb97e72220010ecc
Publikováno v:
Metabolites, Vol 7, Iss 3, p 39 (2017)
Fragrances and malodors are ubiquitous in the environment, arising from natural and artificial processes, by the generation of volatile organic compounds (VOCs). Although VOCs constitute only a fraction of the metabolites produced by an organism, the
Externí odkaz:
https://doaj.org/article/9892bb031605400693973dd084d270bb
Autor:
J Todd Holland, Jason C Harper, Patricia L Dolan, Monica M Manginell, Dulce C Arango, Julia A Rawlings, Christopher A Apblett, Susan M Brozik
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e37924 (2012)
Glucose oxidase (GOx) is an enzymatic workhorse used in the food and wine industries to combat microbial contamination, to produce wines with lowered alcohol content, as the recognition element in amperometric glucose sensors, and as an anodic cataly
Externí odkaz:
https://doaj.org/article/2760b37494304f15beb490ebb3f429f7
Publikováno v:
Drug Delivery
Drug Delivery, Vol 25, Iss 1, Pp 1234-1257 (2018)
Drug Delivery, Vol 25, Iss 1, Pp 1234-1257 (2018)
Gene therapy has long held promise to correct a variety of human diseases and defects. Discovery of the Clustered Regularly-Interspaced Short Palindromic Repeats (CRISPR), the mechanism of the CRISPR-based prokaryotic adaptive immune system (CRISPR-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6c9b148ff7f14452f86e9fee6d7cd0b
https://doi.org/10.1080/10717544.2018.1474964
https://doi.org/10.1080/10717544.2018.1474964
Publikováno v:
ACS Biomaterials Science & Engineering. 3:2098-2109
Over the last twenty years, many strategies utilizing sol-gel chemistry to integrate biological cells into silica-based materials have been reported. One such strategy, Sol-Generating Chemical Vapor into Liquid (SG-CViL) deposition, shows promise as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f28acd5f9d53d6c03e2e75a93968cb09
https://doi.org/10.1021/acsbiomaterials.7b00185
https://doi.org/10.1021/acsbiomaterials.7b00185
Autor:
Jason C. Harper, Eric Jakobsson, Jennifer Pelowitz, C. Jeffrey Brinker, Patrick E. Johnson, Zeeshan Fazal
Publikováno v:
ACS Nano. 11:3560-3575
In order to design hybrid cellular/synthetic devices such as sensors and vaccines, it is important to understand how the metabolic state of living cells changes upon physical confinement within three-dimensional (3D) matrices. We analyze the gene exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::388e198b140c6b78d1b3ef12443663f5
https://doi.org/10.1021/acsnano.6b06385
https://doi.org/10.1021/acsnano.6b06385
Autor:
Jason C. Harper, Edwin A. Saada, Joshua D. Podlevsky, Steven S. Branda, Robert K. Johnston, Jerilyn A. Timlin, Kyle J. Seamon
Publikováno v:
Biosensorsbioelectronics. 141
The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) ribonucleoprotein (RNP) complex is an RNA-guided DNA-nuclease that is part of the bacterial adaptive immune system. CRISPR/Cas9 RNP has been ada
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77917de209c75fe621e8b048abfa658
https://pubmed.ncbi.nlm.nih.gov/31207570
https://pubmed.ncbi.nlm.nih.gov/31207570
Autor:
Darren R. Dunphy, Travis Savage, Svetlana Harbaugh, Jason C. Harper, Nancy Kelley-Loughnane, C. Jeffrey Brinker
Publikováno v:
ACS Biomaterials Science & Engineering. 1:1231-1238
The remarkable impact encapsulation matrix chemistry can have on the bioactivity and viability of integrated living cells is reported. Two silica chemistries (aqueous silicate and alkoxysilane), and a functional component additive (glycerol), are emp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d66d8c882786e4acbc6cbbb4cbbfc393
https://doi.org/10.1021/acsbiomaterials.5b00261
https://doi.org/10.1021/acsbiomaterials.5b00261
Autor:
Jason C. Harper, William Arndt, Melissa Finley, Thayne L. Edwards, C. Jeffrey Brinker, Bryan Carson, George D. Bachand
Publikováno v:
Electroanalysis. 27:2503-2512
D espite significant progress in development of bioanalytical devices cost, complexity ,a ccess to reagents and lack of infrastructure have prevented use of these technologies in resource-limited regions .T op rovide as us- tainable tool in the globa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ca70ed1ff62bc997476d6a679d2703c
https://doi.org/10.1002/elan.201500359
https://doi.org/10.1002/elan.201500359
Publikováno v:
Journal of Materials Chemistry B. 3:1032-1041
In nature, cells perform a variety of complex functions such as sensing, catalysis, and energy conversion which hold great potential for biotechnological device construction. However, cellular sensitivity to ex vivo environments necessitates developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c35802b6f07f4564341f1892014d6fe6
https://doi.org/10.1039/c4tb01349b
https://doi.org/10.1039/c4tb01349b