Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Jason C Grigg"'
Autor:
Julienne C Kaiser, Alyssa N King, Jason C Grigg, Jessica R Sheldon, David R Edgell, Michael E P Murphy, Shaun R Brinsmade, David E Heinrichs
Publikováno v:
PLoS Genetics, Vol 14, Iss 1, p e1007159 (2018)
Staphylococcus aureus requires branched-chain amino acids (BCAAs; isoleucine, leucine, valine) for protein synthesis, branched-chain fatty acid synthesis, and environmental adaptation by responding to their availability via the global transcriptional
Externí odkaz:
https://doaj.org/article/0379a43205b24fb3b33be7c2044d0e2a
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106449 (2014)
The expansion of a (G(4)C(2))n repeat within the human C9orf72 gene has been causally linked to a number of neurodegenerative diseases, most notably familial amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Recent studies have s
Externí odkaz:
https://doaj.org/article/d7e96adb23b94e179c118590c820d6bb
Autor:
Kirstin L. Brown, Kaley M. Wilburn, Christine R. Montague, Jason C. Grigg, Olalla Sanz, Esther Pérez-Herrán, David Barros, Lluís Ballell, Brian C. VanderVen, Lindsay D. Eltis
Publikováno v:
Antimicrobial Agents and Chemotherapy. 67
Despite the deployment of combination tuberculosis (TB) chemotherapy, efforts to identify shorter, nonrelapsing treatments have resulted in limited success. Recent evidence indicates that GSK2556286 (GSK286), which acts via Rv1625c, a membrane-bound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a674ae15e608cbe3e8cd257613cc6b78
https://doi.org/10.1128/aac.01294-22
https://doi.org/10.1128/aac.01294-22
Autor:
Gara N. Dexter, Laura E. Navas, Jason C. Grigg, Harbir Bajwa, David J. Levy-Booth, Jie Liu, Nathan A. Louie, Seyed A. Nasseri, Soo-Kyeong Jang, Scott Renneckar, Lindsay D. Eltis, William W. Mohn
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Bacterial catabolic pathways have considerable potential as industrial biocatalysts for the valorization of lignin, a major component of plant-derived biomass. Here, we describe a pathway responsible for the catabolism of acetovanillone, a major comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85ae8d6bb78ebf343cb0e68e3b7f6062
https://doi.org/10.1073/pnas.2213450119
https://doi.org/10.1073/pnas.2213450119
Autor:
Morgan M. Fetherolf, Gregg T. Beckham, David J. Levy-Booth, Laura E Navas, Jason C. Grigg, William W. Mohn, Rui Katahira, Jie Liu, Lindsay D. Eltis, Andrew Wilson
Publikováno v:
Proc Natl Acad Sci U S A
Cytochrome P450 enzymes have tremendous potential as industrial biocatalysts, including in biological lignin valorization. Here, we describe P450s that catalyze the O-demethylation of lignin-derived guaiacols with different ring substitution patterns
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d49d9fff7f7eed40c4c278a5376d2e0c
https://doi.org/10.1073/pnas.1916349117
https://doi.org/10.1073/pnas.1916349117
Autor:
Laura E. Navas, Michael Zahn, Harbir Bajwa, Jason C. Grigg, Megan E. Wolf, Anson C.K. Chan, Michael E.P. Murphy, John E. McGeehan, Lindsay D. Eltis
Publikováno v:
The Journal of biological chemistry. 298(5)
The actinobacterium Rhodococcus jostii RHA1 grows on a remarkable variety of aromatic compounds and has been studied for applications ranging from the degradation of polychlorinated biphenyls to the valorization of lignin, an underutilized component
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc3048b11a70057acedba4a5b07cd954
https://pubmed.ncbi.nlm.nih.gov/35346686
https://pubmed.ncbi.nlm.nih.gov/35346686
Publikováno v:
BioMetals. 32:409-424
Staphylococcus aureus is a versatile opportunistic human pathogen. Infection by this bacterium requires uptake of iron from the human host, but iron is highly restricted in this environment. Staphylococcus aureus iron sufficiency is achieved primaril
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d6f4c58bfaf34d30318c09e69c9286e
https://doi.org/10.1007/s10534-019-00188-2
https://doi.org/10.1007/s10534-019-00188-2
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2323
Recent studies have solidified RNA's regulatory and catalytic roles in all life forms. Understanding such functions necessarily requires high-resolution understanding of the molecular structure of RNA. Whereas proteins tend to fold into a globular st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8c567f3b030828c591cfb33f8ff09bc7
https://pubmed.ncbi.nlm.nih.gov/34086272
https://pubmed.ncbi.nlm.nih.gov/34086272
Publikováno v:
RNA Scaffolds ISBN: 9781071614983
Recent studies have solidified RNA's regulatory and catalytic roles in all life forms. Understanding such functions necessarily requires high-resolution understanding of the molecular structure of RNA. Whereas proteins tend to fold into a globular st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fec52ea72f05c7021505d62c09ff3ad0
https://doi.org/10.1007/978-1-0716-1499-0_4
https://doi.org/10.1007/978-1-0716-1499-0_4
Publikováno v:
Crystals; Volume 12; Issue 5; Pages: 694
RNAs are prone to misfolding and are often more challenging to crystallize and phase than proteins. Here, we demonstrate that tRNA fusion can streamline the crystallization and structure determination of target RNA molecules. This strategy was applie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b837befbe1536d8f436fd17a91c68652
https://doi.org/10.3390/cryst12050694
https://doi.org/10.3390/cryst12050694