Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Jason C, Ting"'
Autor:
Steven M. Bray, Jeeyun Lee, Seung Tae Kim, Joon Young Hur, Philip J. Ebert, John N. Calley, Isabella H. Wulur, Thejaswini Gopalappa, Swee Seong Wong, Hui-Rong Qian, Jason C. Ting, Jiangang Liu, Melinda D. Willard, Ruslan D. Novosiadly, Young Suk Park, Joon Oh Park, Ho Yeong Lim, Won Ki Kang, Amit Aggarwal, Hee Cheol Kim, Christoph Reinhard
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Abstract Anti-EGFR antibodies are effective in therapies for late-stage colorectal cancer (CRC); however, many tumours are unresponsive or develop resistance. We performed genomic analysis of intrinsic and acquired resistance to anti-EGFR therapy in
Externí odkaz:
https://doaj.org/article/f456fa8deb9947ea89d5b6e8de43eb83
Autor:
Sheng-Bin Peng, Gregory D. Plowman, Ramon V. Tiu, James R. Henry, Amit Aggarwal, Jason C. Ting, Steven Bray, Philip Ebert, Yue Wang Webster, Ruslan D. Novosiadly, Amelie Forest, Robert D. Van Horn, Youyan Zhang, Philip W. Iversen, Gregory P. Donoho, Yung-mae M. Yao
Purpose: To evaluate the antitumor efficacy of cetuximab in combination with LSN3074753, an analog of LY3009120 and pan-RAF inhibitor in 79 colorectal cancer patient-derived xenograft (PDX) models.Experimental Design: Seventy-nine well-characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92cd051fadba964dc0ea8b343c15323d
https://doi.org/10.1158/1078-0432.c.6527070
https://doi.org/10.1158/1078-0432.c.6527070
Autor:
Sheng-Bin Peng, Gregory D. Plowman, Ramon V. Tiu, James R. Henry, Amit Aggarwal, Jason C. Ting, Steven Bray, Philip Ebert, Yue Wang Webster, Ruslan D. Novosiadly, Amelie Forest, Robert D. Van Horn, Youyan Zhang, Philip W. Iversen, Gregory P. Donoho, Yung-mae M. Yao
S1 and S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6b3a64c2b4999a7e270e5e94117a9f5
https://doi.org/10.1158/1078-0432.22468845.v1
https://doi.org/10.1158/1078-0432.22468845.v1
Autor:
Sheng-Bin Peng, Gregory D. Plowman, Ramon V. Tiu, James R. Henry, Amit Aggarwal, Jason C. Ting, Steven Bray, Philip Ebert, Yue Wang Webster, Ruslan D. Novosiadly, Amelie Forest, Robert D. Van Horn, Youyan Zhang, Philip W. Iversen, Gregory P. Donoho, Yung-mae M. Yao
Supplementary Table S1 and S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::633df4b2926f41ff5bb3636f88b806a2
https://doi.org/10.1158/1078-0432.22468842.v1
https://doi.org/10.1158/1078-0432.22468842.v1
Autor:
Pauline C. Ng, Axel M. Hillmer, Patrick Tan, Thomas D. Barber, Geoffrey B. Nilsen, Jason M. Laramie, Dennis G. Ballinger, Stephen E. Lincoln, Brock A. Peters, Daniel S.W. Tan, Christoph Reinhard, Shenli Zhang, Kun Yu, Joanna H.J. Tan, Yuhao Lin, Gary S.L. Loh, Xiwen Ma, Hui-Hoon Chua, Yong G. Yue, Audrey S.M. Teo, Swee-Seong Wong, Elaine Lim, Jason C. Ting, Philip J. Ebert, Vidhya G. Krishnan
Percentage of somatic variants based on 6 mutation types in Asian lung cancers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45dce352d0eaf466ce951ada5f494ef6
https://doi.org/10.1158/0008-5472.22401582.v1
https://doi.org/10.1158/0008-5472.22401582.v1
Autor:
Pauline C. Ng, Axel M. Hillmer, Patrick Tan, Thomas D. Barber, Geoffrey B. Nilsen, Jason M. Laramie, Dennis G. Ballinger, Stephen E. Lincoln, Brock A. Peters, Daniel S.W. Tan, Christoph Reinhard, Shenli Zhang, Kun Yu, Joanna H.J. Tan, Yuhao Lin, Gary S.L. Loh, Xiwen Ma, Hui-Hoon Chua, Yong G. Yue, Audrey S.M. Teo, Swee-Seong Wong, Elaine Lim, Jason C. Ting, Philip J. Ebert, Vidhya G. Krishnan
Clinical and tissue information on 30 lung cancer patients (S1); Recurrent somatic variants based on presence of the same variant in the COSMIC database or presence of the same variant within the dataset (S2); Variants of the category 'three or more
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51477059a67d33d12c240560c586f66c
https://doi.org/10.1158/0008-5472.22401579.v1
https://doi.org/10.1158/0008-5472.22401579.v1
Autor:
Pauline C. Ng, Axel M. Hillmer, Patrick Tan, Thomas D. Barber, Geoffrey B. Nilsen, Jason M. Laramie, Dennis G. Ballinger, Stephen E. Lincoln, Brock A. Peters, Daniel S.W. Tan, Christoph Reinhard, Shenli Zhang, Kun Yu, Joanna H.J. Tan, Yuhao Lin, Gary S.L. Loh, Xiwen Ma, Hui-Hoon Chua, Yong G. Yue, Audrey S.M. Teo, Swee-Seong Wong, Elaine Lim, Jason C. Ting, Philip J. Ebert, Vidhya G. Krishnan
Asian nonsmoking populations have a higher incidence of lung cancer compared with their European counterparts. There is a long-standing hypothesis that the increase of lung cancer in Asian never-smokers is due to environmental factors such as second-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5be768aae2c157cef8b067bfc6eec390
https://doi.org/10.1158/0008-5472.c.6505890
https://doi.org/10.1158/0008-5472.c.6505890
Autor:
Pauline C. Ng, Axel M. Hillmer, Patrick Tan, Thomas D. Barber, Geoffrey B. Nilsen, Jason M. Laramie, Dennis G. Ballinger, Stephen E. Lincoln, Brock A. Peters, Daniel S.W. Tan, Christoph Reinhard, Shenli Zhang, Kun Yu, Joanna H.J. Tan, Yuhao Lin, Gary S.L. Loh, Xiwen Ma, Hui-Hoon Chua, Yong G. Yue, Audrey S.M. Teo, Swee-Seong Wong, Elaine Lim, Jason C. Ting, Philip J. Ebert, Vidhya G. Krishnan
Legend for Supplementary Figures S1-S2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a845a616e2bc05351e5429df3d688fd
https://doi.org/10.1158/0008-5472.22401588.v1
https://doi.org/10.1158/0008-5472.22401588.v1
Autor:
Vincent Vuaroqueaux, Isabella H. Wulur, Swee-Seong Wong, Manuel Landesfeind, Greg Donoho, Kerstin Klingner, Steven M. Bray, Han-Kwang Yang, Peter Bronsert, Anne-Lise Peille, Amit Aggarwal, Seong-Ho Kong, Woo Ho Kim, Bruno Zeitouni, Jason C. Ting, Christoph Reinhard, Nina Zanella, Heinz-Herbert Fiebig, Hyuk-Joon Lee
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-14 (2020)
Communications Biology
Communications Biology
Patient-derived xenografts (PDX) have emerged as an important translational research tool for understanding tumor biology and enabling drug efficacy testing. They are established by transfer of patient tumor into immune compromised mice with the inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f940ae77aa44526abf75dd0444f126e
http://link.springer.com/article/10.1038/s42003-020-1077-z
http://link.springer.com/article/10.1038/s42003-020-1077-z
Autor:
Do-Hyun Nam, Christoph Reinhard, Catherine F. Whittington, Jiangang Liu, Jason C. Ting, Amit Aggarwal, Shripad V. Bhagwat, Hye Kyung Hong, Sheng-Bin Peng, Philip J. Ebert, Steven M. Bray, Woo Yong Lee, John N. Calley, Robert A. Wild, Swee Seong Wong, Yong Beom Cho, Song Wu
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Scientific Reports
Metastasis is the primary cause of cancer mortality. The primary tumors of colorectal cancer (CRC) often metastasize to the liver. In this study, we have collected 122 samples from 45 CRC patients. Among them, 32 patients have primary tumors, adjacen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7fab650116b630c34dbd42e6faf6e4e
http://link.springer.com/article/10.1038/s41598-020-67842-5
http://link.springer.com/article/10.1038/s41598-020-67842-5