Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Jason C, Steel"'
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 13, Iss , Pp 78-88 (2018)
A gene therapeutic platform needs to be both efficient and safe. The criterion of safety is particularly important for diseases like hepatocellular carcinoma (HCC), which develop in a background of an already compromised liver. Gene vectors can be co
Externí odkaz:
https://doaj.org/article/f1da8a9397a54a9897f7a8073787d44e
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background It has been proposed that cancer establishment, maintenance, and recurrence may be attributed to a unique population of tumor cells termed cancer-initiating cells (CICs) that may include characteristics of putative cancer stem cel
Externí odkaz:
https://doaj.org/article/7e02f236f5284faebdcc42ac1d59b3de
Autor:
Angela Armento, Aparna Murali, Julia Marzi, Ana C Almansa-Garcia, Blanca Arango-Gonzalez, Ellen Kilger, Simon J Clark, Katja Schenke-Layland, Charmaine A Ramlogan-Steel, Jason C Steel, Marius Ueffing
Publikováno v:
Biomolecules, Vol 11, Iss 11, p 1621 (2021)
Age-related Macular degeneration (AMD) is a degenerative disease of the macula affecting the elderly population. Treatment options are limited, partly due to the lack of understanding of AMD pathology and the lack of suitable research models that rep
Externí odkaz:
https://doaj.org/article/536089fdaf7f41d9979efdbcd4ffd47f
Publikováno v:
Drug Delivery, Vol 24, Iss 1, Pp 289-299 (2017)
Hepatocellular carcinoma (HCC) is the most common form of primary liver cancer with high incidence globally. Increasing mortality and morbidity rates combined with limited treatment options available for advanced HCC press for novel and effective tre
Externí odkaz:
https://doaj.org/article/33294d228d0040988493b32300a7351d
Publikováno v:
Animals, Vol 11, Iss 2, p 398 (2021)
Pathogen control is re-emerging as a significant challenge to the health of both humans and animals. The livestock industry is in the process of massively replacing in-feed antibiotics with organic production friendly plant-based products. Nutrigenom
Externí odkaz:
https://doaj.org/article/b36207f37593462b96e097d324ff6c84
Publikováno v:
Journal of Hematology & Oncology, Vol 9, Iss 1, Pp 1-12 (2016)
Abstract Hepatocellular carcinoma (HCC) remains one of the most common and lethal malignancies worldwide despite the development of various therapeutic strategies. A better understanding of the mechanisms responsible for HCC initiation and progressio
Externí odkaz:
https://doaj.org/article/3a972d8ca39641689fffaafba6f51f8b
CCR Translation for This Article from Simultaneous Blockade of Multiple Immune System Inhibitory Checkpoints Enhances Antitumor Activity Mediated by Interleukin-15 in a Murine Metastatic Colon Carcinoma Model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a031b1610ef368677e3656b075ef9659
https://doi.org/10.1158/1078-0432.22442441.v1
https://doi.org/10.1158/1078-0432.22442441.v1
Purpose: Interleukin 15 (IL-15) is a promising cytokine for immunotherapy of cancer due to its ability to stimulate the immunity of natural killer, B, and T cells. Its effectiveness, however, may be limited by inhibitory checkpoints and pathways that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a890a02550a842d8206d2ab935be1c95
https://doi.org/10.1158/1078-0432.c.6519158
https://doi.org/10.1158/1078-0432.c.6519158
Autor:
Zaw Thet, Alfred K. Lam, Tony Pham, Shu‐Kay Ng, Jason C. Steel, Sirena Sawhney, Carolina T. Arellano, Soe Yu Aung, Thin Han, Dwarakanathan Ranganathan, George John, Christina Pepito, Tamlyn Rautenberg, Tien K. Khoo
Publikováno v:
Internal Medicine Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::096c4130b0339d62a64ce13d8a1020c4
https://doi.org/10.1111/imj.16024
https://doi.org/10.1111/imj.16024
Publikováno v:
Expert Reviews in Molecular Medicine. 25
Cancer metastasis is the primary cause of cancer-related deaths. The seeding of primary tumours at a secondary site is a highly inefficient process requiring substantial alterations in the genetic architecture of cancer cells. These alterations inclu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d65bee85fc2c8fde2fe5a95208387bab
https://doi.org/10.1017/erm.2023.7
https://doi.org/10.1017/erm.2023.7