Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jason Burbank"'
Publikováno v:
Applied Thermal Engineering. 96:107-116
A control technique to optimize an existing de-coupled primary-secondary ground source heat pump (GSHP) loop system using site data is presented. The proposed control algorithm improves system performance by optimizing the primary loop pump's flow of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::133468ed3e2e4ae8fa207d539e2c0332
https://doi.org/10.1016/j.applthermaleng.2015.10.027
https://doi.org/10.1016/j.applthermaleng.2015.10.027
Autor:
Alex Kentsis, A. Thomas Look, James E. Bradner, Frederic Baleydier, Ruta Grebliunaite, Jon C. Aster, Huipin Yuan, Andrew P. Weng, Françoise Pflumio, Li Pan, Lynn VerPlank, Jason J. Marineau, Stephanie Norton, Richard W.J. Groen, Frank An, Jason Burbank, Benjamin Uzan, Constantine S. Mitsiades, Hanno Steen, Sandrine Poglio, Nicola Tolliday, Casie Reed, Elena Kozakewich, Paul A. Clemons, Alejandro Gutierrez
Publikováno v:
Journal of Clinical Investigation, 124(2), 644-55. The American Society for Clinical Investigation
Gutierrez, A, Pan, L, Groen, R W J, Baleydier, F, Kentsis, A, Marineau, J, Grebliunaite, R, Kozakewich, E, Reed, C, Pflumio, F, Poglio, S, Uzan, B, Clemons, P, VerPlank, L, An, F, Burbank, J, Norton, S, Tolliday, N, Steen, H, Weng, A P, Yuan, H, Bradner, J E, Mitsiades, C, Look, A T & Aster, J C 2014, ' Phenothiazines induce PP2A-mediated apoptosis in T cell acute lymphoblastic leukemia ', Journal of Clinical Investigation, vol. 124, no. 2, pp. 644-55 . https://doi.org/10.1172/JCI65093
Gutierrez, A, Pan, L, Groen, R W J, Baleydier, F, Kentsis, A, Marineau, J, Grebliunaite, R, Kozakewich, E, Reed, C, Pflumio, F, Poglio, S, Uzan, B, Clemons, P, VerPlank, L, An, F, Burbank, J, Norton, S, Tolliday, N, Steen, H, Weng, A P, Yuan, H, Bradner, J E, Mitsiades, C, Look, A T & Aster, J C 2014, ' Phenothiazines induce PP2A-mediated apoptosis in T cell acute lymphoblastic leukemia ', Journal of Clinical Investigation, vol. 124, no. 2, pp. 644-55 . https://doi.org/10.1172/JCI65093
T cell acute lymphoblastic leukemia (T-ALL) is an aggressive cancer that is frequently associated with activating mutations in NOTCH1 and dysregulation of MYC. Here, we performed 2 complementary screens to identify FDA-approved drugs and drug-like sm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42754d1bf080836a1fcd220ac6453f2e
https://doi.org/10.1172/jci65093
https://doi.org/10.1172/jci65093
Autor:
Li Pan, James E. Bradner, Sandrine Poglio, Alejandro Gutierrez, Frank An, Richard W.J. Groen, Casie Reed, Constantine S. Mitsiades, Huipin Yuan, Alex Kentsis, Ruta Grebliunaite, Lynn VerPlank, Jason J. Marineau, Jon C. Aster, A. Thomas Look, Jason Burbank, Benjamin Uzan, Andrew P. Weng, Stephanie Norton, Frederic Baleydier, Elena Kozakewich, Paul A. Clemons, Françoise Pflumio, Nicola Tolliday, Hanno Steen
Publikováno v:
Molecular Cancer Research. 12:IA8-IA8
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive cancer frequently associated with activating NOTCH1 mutations and dysregulation of MYC. We performed two complementary screens to identify novel agents with activity against T-ALL: i) a zeb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43d40aa7a233672bf212a85feaade6eb
https://doi.org/10.1158/1557-3125.modorg-ia8
https://doi.org/10.1158/1557-3125.modorg-ia8
Autor:
Lynn VerPlank, Elena Kozakewich, Sandrine Poglio, Casie Reed, Jason J. Marineau, Alejandro Gutierrez, Alex Kentsis, Hanno Steen, Frederic Baleydier, A. Thomas Look, James E. Bradner, Li Pan, Paul A. Clemons, Nicola Tolliday, Jon C. Aster, W. Frank An, Ruta Grebliunaite, Stephanie Norton, Françoise Pflumio, Jason Burbank, Benjamin Uzan
Publikováno v:
Blood. 120:3558-3558
Abstract 3558 Despite the use of intensive and toxic treatment regimens, T-cell acute lymphoblastic leukemia (T-ALL) remains fatal in 25% of children and 60% of adults, highlighting the need for novel therapeutic strategies. We performed two compleme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64c3e100d8fb46633c5135e35e41ee7d
https://doi.org/10.1182/blood.v120.21.3558.3558
https://doi.org/10.1182/blood.v120.21.3558.3558
Autor:
Jason Burbank, Lynn VerPlank, James R. Dilks, Price S. Blair, Robert Gould, Albert Mairuhu, Michelle Palmer, Robert Flaumenhaft, Lawrence MacPherson, Gil Walzer, Tyler Aldredge, Chris Dockendorff, Joseph Negri
Publikováno v:
Blood. 114:4009-4009
Abstract 4009 Poster Board III-945 Platelets are anucleate cells that are not amenable to traditional forward genetic analysis. In collaboration with the Broad Institute Probe Development Center, we have performed a chemical genetic analysis of plate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53c3e59b1c7cedbedf852701d6f7ced3
https://doi.org/10.1182/blood.v114.22.4009.4009
https://doi.org/10.1182/blood.v114.22.4009.4009