Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Jason Bugno"'
Autor:
Xi Jiang, Chao Hu, Stephen Arnovitz, Jason Bugno, Miao Yu, Zhixiang Zuo, Ping Chen, Hao Huang, Bryan Ulrich, Sandeep Gurbuxani, Hengyou Weng, Jennifer Strong, Yungui Wang, Yuanyuan Li, Justin Salat, Shenglai Li, Abdel G. Elkahloun, Yang Yang, Mary Beth Neilly, Richard A. Larson, Michelle M. Le Beau, Tobias Herold, Stefan K. Bohlander, Paul P. Liu, Jiwang Zhang, Zejuan Li, Chuan He, Jie Jin, Seungpyo Hong, Jianjun Chen
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Mir-22 has been shown to be an oncogenic microRNA in breast cancer and myelodysplastic syndrome. Here, the authors show that mir-22 functions as a tumour suppressor in de novoacute myeloid leukaemia by inhibiting the expression of several oncogenes a
Externí odkaz:
https://doaj.org/article/f6c55704ac9d48718faf67aaba2ba41b
Autor:
Ashita Nair, Kaila Javius-Jones, Jason Bugno, Michael J. Poellmann, Narsimha Mamidi, In-San Kim, Ick Chan Kwon, Heejoo Hong, Seungpyo Hong
Publikováno v:
Chemistry of Materials. 35:3138-3150
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67cf7879de812dffcff25fa40297792d
https://doi.org/10.1021/acs.chemmater.2c03705
https://doi.org/10.1021/acs.chemmater.2c03705
Autor:
Kaiting Yang, Wenbo Han, Xiaomin Jiang, Andras Piffko, Jason Bugno, Chuanhui Han, Sirui Li, Hua Liang, Ziwan Xu, Wenxin Zheng, Liangliang Wang, Jiaai Wang, Xiaona Huang, Jenny P. Y. Ting, Yang-Xin Fu, Wenbin Lin, Ralph R. Weichselbaum
Publikováno v:
Nature Nanotechnology. 17:1322-1331
The clinical utility of stimulator of interferon genes (STING) agonists has been limited due to poor tumour-targeting and unwanted toxicity following systemic delivery. Here we describe a robust tumour-targeted STING agonist, ZnCDA, formed by the enc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38646603011bd17013097860035662ed
https://doi.org/10.1038/s41565-022-01225-x
https://doi.org/10.1038/s41565-022-01225-x
Autor:
Liangliang Wang, Xiaoyang Dou, Shijie Chen, Xianbin Yu, Xiaona Huang, Linda Zhang, Yantao Chen, Jiaai Wang, Kaiting Yang, Jason Bugno, Sean Pitroda, Xingchen Ding, Andras Piffko, Wei Si, Chao Chen, Hualiang Jiang, Bing Zhou, Steven J. Chmura, Cheng Luo, Hua Laura Liang, Chuan He, Ralph R. Weichselbaum
Publikováno v:
Cancer Cell.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7c15c9f4bc9650acf23805887c0a68d
https://doi.org/10.1016/j.ccell.2023.04.019
https://doi.org/10.1016/j.ccell.2023.04.019
Autor:
Jianjun Chen, Seungpyo Hong, James E. Bradner, Zejuan Li, Jie Jin, Stefan K. Bohlander, Michelle M. Le Beau, Richard A. Larson, Mary Beth Neilly, Shenglai Li, Hao Huang, Yungui Wang, Hengyou Weng, Bryan Ulrich, Kyle Ferchen, Jennifer Strong, Stephen Arnovitz, Sandeep Gurbuxani, Ping Chen, Jun Qi, Tobias Herold, Yang Yang, Chao Hu, Jason Bugno, Xi Jiang
Effects of JQ1 and/or miR-150 nanoparticles on mouse blood cell differentiation four weeks after the last administration of drugs or control (PBS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdaba81a01eee3b139b1621a63ecd9f6
https://doi.org/10.1158/0008-5472.22408808.v1
https://doi.org/10.1158/0008-5472.22408808.v1
Autor:
Jianjun Chen, Seungpyo Hong, James E. Bradner, Zejuan Li, Jie Jin, Stefan K. Bohlander, Michelle M. Le Beau, Richard A. Larson, Mary Beth Neilly, Shenglai Li, Hao Huang, Yungui Wang, Hengyou Weng, Bryan Ulrich, Kyle Ferchen, Jennifer Strong, Stephen Arnovitz, Sandeep Gurbuxani, Ping Chen, Jun Qi, Tobias Herold, Yang Yang, Chao Hu, Jason Bugno, Xi Jiang
Acute myeloid leukemia (AML) is a common and fatal form of hematopoietic malignancy. Overexpression and/or mutations of FLT3 have been shown to occur in the majority of cases of AML. Our analysis of a large-scale AML patient cohort (N = 562) indicate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d63575cb63424a9c51da353cdff6b5b
https://doi.org/10.1158/0008-5472.c.6507626
https://doi.org/10.1158/0008-5472.c.6507626
Autor:
Jianjun Chen, Seungpyo Hong, James E. Bradner, Zejuan Li, Jie Jin, Stefan K. Bohlander, Michelle M. Le Beau, Richard A. Larson, Mary Beth Neilly, Shenglai Li, Hao Huang, Yungui Wang, Hengyou Weng, Bryan Ulrich, Kyle Ferchen, Jennifer Strong, Stephen Arnovitz, Sandeep Gurbuxani, Ping Chen, Jun Qi, Tobias Herold, Yang Yang, Chao Hu, Jason Bugno, Xi Jiang
Clinical and molecular characteristics of the AML patients in GSE37642 cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce3345f34d582958dbd0be4cb69ac45
https://doi.org/10.1158/0008-5472.22408817.v1
https://doi.org/10.1158/0008-5472.22408817.v1
Autor:
Jianjun Chen, Seungpyo Hong, James E. Bradner, Zejuan Li, Jie Jin, Stefan K. Bohlander, Michelle M. Le Beau, Richard A. Larson, Mary Beth Neilly, Shenglai Li, Hao Huang, Yungui Wang, Hengyou Weng, Bryan Ulrich, Kyle Ferchen, Jennifer Strong, Stephen Arnovitz, Sandeep Gurbuxani, Ping Chen, Jun Qi, Tobias Herold, Yang Yang, Chao Hu, Jason Bugno, Xi Jiang
Legends for supplemental figures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120a2cd51265a905fa166b4015800af8
https://doi.org/10.1158/0008-5472.22408805
https://doi.org/10.1158/0008-5472.22408805
Autor:
Jianjun Chen, Seungpyo Hong, James E. Bradner, Zejuan Li, Jie Jin, Stefan K. Bohlander, Michelle M. Le Beau, Richard A. Larson, Mary Beth Neilly, Shenglai Li, Hao Huang, Yungui Wang, Hengyou Weng, Bryan Ulrich, Kyle Ferchen, Jennifer Strong, Stephen Arnovitz, Sandeep Gurbuxani, Ping Chen, Jun Qi, Tobias Herold, Yang Yang, Chao Hu, Jason Bugno, Xi Jiang
Effects of the nanoparticles on mouse blood cell differentiation two (A) or four (B) weeks after the last administration of nanoparticles or control (PBS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27c63cd5c574aeed79c222046c58e541
https://doi.org/10.1158/0008-5472.22408814.v1
https://doi.org/10.1158/0008-5472.22408814.v1
Autor:
Jianjun Chen, Seungpyo Hong, James E. Bradner, Zejuan Li, Jie Jin, Stefan K. Bohlander, Michelle M. Le Beau, Richard A. Larson, Mary Beth Neilly, Shenglai Li, Hao Huang, Yungui Wang, Hengyou Weng, Bryan Ulrich, Kyle Ferchen, Jennifer Strong, Stephen Arnovitz, Sandeep Gurbuxani, Ping Chen, Jun Qi, Tobias Herold, Yang Yang, Chao Hu, Jason Bugno, Xi Jiang
Supplemental Figure 1. Construction of G7-FLT3L dendrimers and their uptake ratio in AML cells. Supplemental Figure 2. G7 PAMAM dendrimers efficiently complex small, single stranded oligonucleotides. Supplemental Figure 3. G7-FLT3L-miR-150 nanopartic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e36fd9b9f4e902a3ab158241f2aa49e4
https://doi.org/10.1158/0008-5472.22408820
https://doi.org/10.1158/0008-5472.22408820