Meeting abstracts from the 15th international conference on neonatal and childhood pulmonary vascular disease

Autor: Jason Boehme, Steven Abman, Jeffrey Fineman

Publikováno v: Pulmonary Circulation, Vol 12, Iss 2, Pp n/a-n/a (2022)

Externí odkaz: https://doaj.org/article/3a58d57d22e94a3a8fb0f57c71127dc5

Preservation of myocardial contractility during acute hypoxia with OMX-CV, a novel oxygen delivery biotherapeutic.

Autor: Jason Boehme, Natacha Le Moan, Rebecca J Kameny, Alexandra Loucks, Michael J Johengen, Amy L Lesneski, Wenhui Gong, Brian D. Goudy, Tina Davis, Kevin Tanaka, Andrew Davis, Youping He, Janel Long-Boyle, Vijay Ivaturi, Jogarao V S Gobburu, Jonathan A Winger, Stephen P Cary, Sanjeev A Datar, Jeffrey R Fineman, Ana Krtolica, Emin Maltepe

Publikováno v: PLoS Biology, Vol 16, Iss 10, p e2005924 (2018)

The heart exhibits the highest basal oxygen (O2) consumption per tissue mass of any organ in the body and is uniquely dependent on aerobic metabolism to sustain contractile function. During acute hypoxic states, the body responds with a compensatory

Externí odkaz: https://doaj.org/article/e13aa0d7d62a4167b657b0418bb3eb3f

HIF-1α promotes cellular growth in lymphatic endothelial cells exposed to chronically elevated pulmonary lymph flow

Autor: Gary W. Raff, Sanjeev A. Datar, Jason Boehme, Wenhui Gong, Emin Maltepe, Jeffrey R. Fineman, Katherine Y. Wu, Samuel R. Chiacchia, Rebecca J Kameny, Catherine Morris

Publikováno v: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific reports, vol 11, iss 1

Normal growth and development of lymphatic structures depends on mechanical forces created by accumulating interstitial fluid. However, prolonged exposure to pathologic mechanical stimuli generated by chronically elevated lymph flow results in lympha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ce6ed1dd0248eb1ec5a6c57628c281b
http://europepmc.org/articles/PMC7809484

Analysis of the microRNA signature driving adaptive right ventricular hypertrophy in an ovine model of congenital heart disease

Autor: Youping He, Terry Zhu, Jeffrey R. Fineman, Cheryl J. Chapin, Jason Boehme, Gary W. Raff, Rebecca J Kameny, Wenhui Gong, Sanjeev A. Datar, Akiko Hata

Publikováno v: American journal of physiology. Heart and circulatory physiology, vol 315, iss 4
Kameny, Rebecca Johnson; He, Youping; Zhu, Terry; Gong, Wenhui; Raff, Gary W; Chapin, Cheryl J; et al.(2018). Analysis of the microRNA signature driving adaptive right ventricular hypertrophy in an ovine model of congenital heart disease.. American journal of physiology. Heart and circulatory physiology, 315(4), H847-H854. doi: 10.1152/ajpheart.00057.2018. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/9j7783r0

The right ventricular (RV) response to pulmonary arterial hypertension (PAH) is heterogeneous. Most patients have maladaptive changes with RV dilation and RV failure, whereas some, especially patients with PAH secondary to congenital heart disease, h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57881c7de76f694cd39d9d79bc188559
https://doi.org/10.1152/ajpheart.00057.2018

Mechanical Forces Alter Endothelin-1 Signaling: Comparative Ovine Models of Congenital Heart Disease

Autor: Terry Zhu, Rebecca J Kameny, Jeffrey R. Fineman, Sanjeev A. Datar, Jason Boehme, Gary W. Raff, Juan C. Lasheras, Stephen M. Black, Emin Maltepe, Antoni Garcia-Herreros

Publikováno v: Biophysical Journal. 118:251a-252a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a994861879871d7f20e068d6fd482674
https://doi.org/10.1016/j.bpj.2019.11.1471