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Autor:
Jason B. Schultz, Jan Johnson, Tamayuki Shinomura, Satoshi Nuka, Ramiro Ramírez-Solis, Stephen P. Henry, Richard R. Behringer, Magnus Höök, Wei Zhou, Marian F. Young, Christi Gendron, Ying Wang, Douglas R. Keene
Publikováno v:
Osteoarthritis and Cartilage. 18(1):88-96
Summary Objective To characterize the in vivo role epiphycan ( Epn ) has in cartilage development and/or maintenance. Methods Epn -deficient mice were generated by disrupting the Epn gene in mouse embryonic stem cells. Epn /biglycan ( Bgn ) double-de