Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jason Aungst"'
Autor:
Jie Liu, Wenjing Guo, Fan Dong, Jason Aungst, Suzanne Fitzpatrick, Tucker A. Patterson, Huixiao Hong
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Reproductive toxicity is one of the prominent endpoints in the risk assessment of environmental and industrial chemicals. Due to the complexity of the reproductive system, traditional reproductive toxicity testing in animals, especially guideline mul
Externí odkaz:
https://doaj.org/article/93aa5e8b1c6f4fa08318b9e18e120061
Publikováno v:
Biomolecules, Vol 13, Iss 1, p 5 (2022)
The safety evaluation of oral exposure to substances, such as food ingredients, additives, and their constituents, relies primarily on a careful evaluation and analysis of data from oral toxicity studies. When relevant oral toxicity studies are unava
Externí odkaz:
https://doaj.org/article/c8cd9e8be38f41268c31d9d662555cc0
Publikováno v:
Food and Chemical Toxicology. 112:375-382
Polyfluorinated compounds (PFCs) are authorized for use as greaseproofing agents in food contact paper. As C8-PFCs (8-carbons) are known to accumulate in tissues, shorter-chain C6-PFCs (6-carbons) have replaced C8-PFCs in many food contact applicatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4760991cc4d5a613367deaa6874e87e
https://doi.org/10.1016/j.fct.2018.01.012
https://doi.org/10.1016/j.fct.2018.01.012
Publikováno v:
Food and Chemical Toxicology. 145:111755
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fedd94ae20acd17d35427bdb46d950c6
https://doi.org/10.1016/j.fct.2020.111755
https://doi.org/10.1016/j.fct.2020.111755
Publikováno v:
Food and Chemical Toxicology. 139:111249
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4221d2f751038851bd63841ac8e709f
https://doi.org/10.1016/j.fct.2020.111249
https://doi.org/10.1016/j.fct.2020.111249
Publikováno v:
Food and Chemical Toxicology. 138:111210
6:2 Fluorotelomer alcohol (6:2 FTOH) is a short-chain polyfluoroalkyl substance (PFAS) in polymeric PFAS used in fast food packaging and stain- and water-resistant textiles and may be degradation products of some components of aqueous film-forming fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c50292f500b84844cf0035ef349ec9da
https://doi.org/10.1016/j.fct.2020.111210
https://doi.org/10.1016/j.fct.2020.111210
Autor:
Shruti V. Kabadi, Daniel R. Doerge, Jason Aungst, Darshan Mehta, Penelope A. Rice, Jeffrey W. Fisher
Publikováno v:
Toxicology and Applied Pharmacology. 388:114878
Our previous report on pharmacokinetic (PK) evaluation of 6:2 fluorotelomer alcohol (6:2 FTOH) examined the biopersistence potential of its metabolites based on data published from single inhalation and occupational 6:2 FTOH exposure studies. We calc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de87d4a03fd92c012674ce760fb21751
https://doi.org/10.1016/j.taap.2020.114878
https://doi.org/10.1016/j.taap.2020.114878
Publikováno v:
Toxicology and Applied Pharmacology. 382:114759
The use of toxicokinetic (TK) data is becoming more prevalent in the evaluation of food ingredient safety as more TK information is being incorporated in safety data packages. Data demonstrating “1) the extent of absorption, 2) tissue distribution,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79d6c22982d40f44e05189f8d77e0263
https://doi.org/10.1016/j.taap.2019.114759
https://doi.org/10.1016/j.taap.2019.114759
Autor:
Paul C. Howard, Nigel J. Walker, K. Barry Delclos, Retha R. Newbold, R. Thomas Zoeller, Anne F. Johnson, Dennis Keefe, John R. Bucher, Thaddeus T. Schug, Jerrold J. Heindel, Luísa Camacho, Jason Aungst
Publikováno v:
Reproductive Toxicology. 40:35-40
Recently, medical research has seen a strong push toward translational research, or "bench to bedside" collaborations, that strive to enhance the utility of laboratory science for improving medical treatment. The success of that paradigm supports the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d18c1bb076a3c5642167c532f2ba7211
https://doi.org/10.1016/j.reprotox.2013.05.010
https://doi.org/10.1016/j.reprotox.2013.05.010
Autor:
Huixiao Hong, Lei Xu, Roger Perkins, Abigail Jacobs, Susie Y. Dai, Jeffrey D. Bray, Wafa Harrouk, Richard S. Judson, Zhenqiang Su, Guangxu Zhou, Weigong Ge, Hong Fang, Thomas Colatsky, Ann M. Richard, Stephen C. Harris, Jason Aungst, Weida Tong, Christina T. Teng, Jie Shen
Publikováno v:
Toxicological Sciences. 135:277-291
Endocrine-active chemicals can potentially have adverse effects on both humans and wildlife. They can interfere with the body's endocrine system through direct or indirect interactions with many protein targets. Estrogen receptors (ERs) are one of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f906da1ca463ff5497ee0f2e59034a
https://doi.org/10.1093/toxsci/kft164
https://doi.org/10.1093/toxsci/kft164