Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jason Arsenault"'
Autor:
Lu-Yang Wang, Tian Kong, David R. Hampson, Enea Koxhioni, Yosuke Niibori, James H. Eubanks, Alexander W.M. Hooper, Shervin Gholizadeh, Jason Arsenault, Laura K. K. Pacey
Publikováno v:
Human Molecular Genetics
Several X-linked neurodevelopmental disorders including Rett syndrome, induced by mutations in the MECP2 gene, and fragile X syndrome (FXS), caused by mutations in the FMR1 gene, share autism-related features. The mRNA coding for methyl CpG binding p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5597bf9877fb975144e909fff1b7f96
https://doi.org/10.1093/hmg/ddaa226
https://doi.org/10.1093/hmg/ddaa226
Autor:
Julie D. Forman-Kay, Nahum Sonenberg, Alaji Bah, Brian Tsang, Robert M. Vernon, Jason Arsenault, Lu-Yang Wang, Hong Lin
Publikováno v:
Proceedings of the National Academy of Sciences. 116:4218-4227
Activity-dependent translation requires the transport of mRNAs within membraneless protein assemblies known as neuronal granules from the cell body toward synaptic regions. Translation of mRNA is inhibited in these granules during transport but quick
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0092db22e0192095a50a213dea48627
https://doi.org/10.1073/pnas.1814385116
https://doi.org/10.1073/pnas.1814385116
Autor:
Stephen P. Hunt, Michelangelo Certo, Maria Maiarù, Bazbek Davletov, Charlotte Leese, Antonina Stefania Mangione, Jason Arsenault, Irene Echeverria-Altuna
Publikováno v:
Science translational medicine. 10(450)
Chronic pain is a widespread debilitating condition affecting millions of people worldwide. Although several pharmacological treatments for relieving chronic pain have been developed, they require frequent chronic administration and are often associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a51aee637350d6dbf4ff6a38f2b79b1
https://pubmed.ncbi.nlm.nih.gov/30021888
https://pubmed.ncbi.nlm.nih.gov/30021888
Autor:
Laura K. K. Pacey, Mickael Krzeminski, Alaji Bah, Owen Y. Chao, David R. Hampson, Lu-Yang Wang, Julie D. Forman-Kay, Jason Arsenault, Yi Mei Yang, Adam Fekete, Alexander Wang
Publikováno v:
Molecular Psychiatry
Principal neurons encode information by varying their firing rate and patterns precisely fine-tuned through GABAergic interneurons. Dysregulation of inhibition can lead to neuropsychiatric disorders, yet little is known about the molecular basis unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d1cf961bfa31a03eb4502d880077dba
https://pubmed.ncbi.nlm.nih.gov/30224722
https://pubmed.ncbi.nlm.nih.gov/30224722
Autor:
Hayato Terayama, Carolyn L. Cummins, Yosuke Niibori, Charlotte Pidgeon, David R. Hampson, Andrew P. Burke, Masatoshi Ito, Jason Arsenault, Rafael Mateo, Kou Sakabe, Pablo R. Camarero
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
instname
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
Neonicotinoids have become the most widely used class of insecticides world-wide. Although numerous studies have documented neonicotinoid toxicity in bees and other insects, the effects of exposure during early development in mammals remain largely u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da032b57800e80e8085b5a90f7b25b4
http://hdl.handle.net/10261/174747
http://hdl.handle.net/10261/174747
Publikováno v:
Journal of Cellular Biochemistry
Transfection of DNA has been invaluable for biological sciences, yet the effects upon membrane homeostasis are far from negligible. Here, we demonstrate that Neuro2A cells transfected using Lipofectamine LTX with the fluorescently coupled Botulinum s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b4d57936985f9c37620946d95335cc9
https://doi.org/10.1002/jcb.24884
https://doi.org/10.1002/jcb.24884
Autor:
Hirokazu Hirai, Ayumu Konno, Enea Koxhioni, Yosuke Niibori, David R. Hampson, Shervin Gholizadeh, Sebok Kumar Halder, Laura K. K. Pacey, Jason Arsenault
Publikováno v:
Human Gene Therapy
Fragile X mental retardation protein (FMRP) is absent or highly reduced in Fragile X Syndrome, a genetic disorder causing cognitive impairment and autistic behaviors. Previous proof-of-principle studies have demonstrated that restoring FMRP in the br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a83ff2ccc43a93521507a35a21dcb20e
https://pubmed.ncbi.nlm.nih.gov/27604541
https://pubmed.ncbi.nlm.nih.gov/27604541
Autor:
Jason Arsenault, Gaétan Guillemette, Jérôme Cabana, Pierre Lavigne, Emanuel Escher, Luc Lanthier, Richard Leduc, Julie Lehoux
Publikováno v:
Pharmacogenetics and Genomics. 20:377-388
AT1 is the principal receptor for angiotensin II (AngII), which regulates blood pressure and osmotic homeostasis. Earlier studies have shown that position 163 interacts with the antihypertensive nonpeptide antagonist, Losartan. A recently discovered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cd3bf60a23f1004459d6d4033924bca
https://doi.org/10.1097/fpc.0b013e32833a6d4a
https://doi.org/10.1097/fpc.0b013e32833a6d4a
Publikováno v:
Endocrine. 37:442-448
A novel binding site for angiotensins II and III was recently discovered in brain membranes in the presence of the sulfhydryl reactive angiotensinase inhibitor parachloromercuribenzoate. This binding site is distinctly different from the other known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d1bffffc826de3b058c445599a85a64
https://doi.org/10.1007/s12020-010-9328-2
https://doi.org/10.1007/s12020-010-9328-2
Autor:
Gaétan Guillemette, Emanuel Escher, Martin Clément, M. P. La Haye Renaud, Richard Leduc, Pierre Lavigne, Dany Fillion, Jason Arsenault
Publikováno v:
Journal of Peptide Science. 13:575-580
Photoaffinity labelling is regularly used to investigate proteins, including peptidergic G protein-coupled receptors (GPCR). To this purpose benzophenone photolabels have been widely used to identify many contact residues in ligand-binding pockets. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::149aa0464197493b5d4edcdf69548e57
https://doi.org/10.1002/psc.875
https://doi.org/10.1002/psc.875