Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jason A. Wagoner"'
Autor:
Jasmine Cubuk, Jhullian J. Alston, J. Jeremías Incicco, Sukrit Singh, Melissa D. Stuchell-Brereton, Michael D. Ward, Maxwell I. Zimmerman, Neha Vithani, Daniel Griffith, Jason A. Wagoner, Gregory R. Bowman, Kathleen B. Hall, Andrea Soranno, Alex S. Holehouse
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
SARS-CoV-2 nucleocapsid (N) protein is responsible for viral genome packaging. Here the authors employ single-molecule spectroscopy with all-atom simulations to provide the molecular details of N protein and show that it undergoes phase separation wi
Externí odkaz:
https://doaj.org/article/dd6a306bbe1846f28cbf4f152c659197
Autor:
Jason A. Wagoner, Ken A. Dill
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 116, iss 13
How does a biomolecular machine achieve high speed at high efficiency? We explore optimization principles using a simple two-state dynamical model. With this model, we establish physical principles—such as the optimal way to distribute free-energy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ecefe8c88025ccc83ff50dcfef25942
https://doi.org/10.1073/pnas.1812149116
https://doi.org/10.1073/pnas.1812149116
Autor:
Jason A. Wagoner, Ken A. Dill
Publikováno v:
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America, vol 118, iss 20
Proceedings of the National Academy of Sciences of the United States of America, vol 118, iss 20
Myosin II is a biomolecular machine that is responsible for muscle contraction. Myosin II motors act cooperatively: during muscle contraction, multiple motors bind to a single actin filament and pull it against an external load, like people pulling o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efd72503d2112a142e686ba388b197c1
https://pubmed.ncbi.nlm.nih.gov/33975956
https://pubmed.ncbi.nlm.nih.gov/33975956
Autor:
Jason A. Wagoner, Andrea Soranno, Jhullian J. Alston, Daniel Griffith, Neha Vithani, Melissa D. Stuchell-Brereton, Alex S. Holehouse, Sukrit Singh, J. Jeremías Incicco, Kathleen B. Hall, Maxwell I. Zimmerman, Michael D. Ward, Jasmine Cubuk, Gregory R. Bowman
Publikováno v:
bioRxiv
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
The SARS-CoV-2 nucleocapsid (N) protein is an abundant RNA-binding protein critical for viral genome packaging, yet the molecular details that underlie this process are poorly understood. Here we combine single-molecule spectroscopy with all-atom sim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a8d3efe10b2f38c340758592501033
https://pubmed.ncbi.nlm.nih.gov/32587966
https://pubmed.ncbi.nlm.nih.gov/32587966
Autor:
Jason A. Wagoner
Publikováno v:
Biophysical Journal. 118:119a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a48b7cc5fe700ae84189254e6e2caa00
https://doi.org/10.1016/j.bpj.2019.11.791
https://doi.org/10.1016/j.bpj.2019.11.791
Autor:
Jason A. Wagoner, Vijay S. Pande
Combined-resolution simulations are an effective way to study molecular properties across a range of length and time scales. These simulations can benefit from adaptive boundaries that allow the high-resolution region to adapt (change size and/or sha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9012da52681c7b858c07f3f49427d8b6
https://europepmc.org/articles/PMC5909991/
https://europepmc.org/articles/PMC5909991/
Autor:
Jason A. Wagoner, Ken A. Dill
Publikováno v:
The journal of physical chemistry. B. 120(26)
Molecular motors convert chemical energy (typically from ATP hydrolysis) to directed motion and mechanical work. Their actions are often described in terms of "Power Stroke" (PS) and "Brownian Ratchet" (BR) mechanisms. Here, we use a transition-state
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5018b6304ec2f72b4b343747dc574eba
https://pubmed.ncbi.nlm.nih.gov/27136319
https://pubmed.ncbi.nlm.nih.gov/27136319
Autor:
Jason A. Wagoner, Ken A. Dill
Publikováno v:
Biophysical Journal. 114:519a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e98c001bad9531730a06f68067e33ce
https://doi.org/10.1016/j.bpj.2017.11.2837
https://doi.org/10.1016/j.bpj.2017.11.2837
Publikováno v:
Journal of Chemical Theory and Computation. 3:170-183
Accurate implicit solvent models require parameters that have been optimized in a system- or atom-specific manner on the basis of experimental data or more rigorous explicit solvent simulations. Models based on the Poisson or Poisson-Boltzmann equati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d48ad45c4031b70edaf524813e6cdd8
https://doi.org/10.1021/ct600216k
https://doi.org/10.1021/ct600216k
Autor:
Jason A. Wagoner, Nathan A. Baker
Publikováno v:
Journal of Computational Chemistry. 25:1623-1629
Continuum electrostatics methods have become increasingly popular due to their ability to provide approximate descriptions of solvation energies and forces without expensive sampling required by explicit solvent models. In particular, the Poisson-Bol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a4396820f9de533c30853613e451a8f
https://doi.org/10.1002/jcc.20089
https://doi.org/10.1002/jcc.20089