Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Jason A. Skinner"'
Autor:
Martin Grashei, Pascal Wodtke, Jason G. Skinner, Sandra Sühnel, Nadine Setzer, Thomas Metzler, Sebastian Gulde, Mihyun Park, Daniela Witt, Hermine Mohr, Christian Hundshammer, Nicole Strittmatter, Natalia S. Pellegata, Katja Steiger, Franz Schilling
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract pH alterations are a hallmark of many pathologies including cancer and kidney disease. Here, we introduce [1,5-13C2]Z-OMPD as a hyperpolarized extracellular pH and perfusion sensor for MRI which allows to generate a multiparametric fingerpri
Externí odkaz:
https://doaj.org/article/e47e9472da1b44daad591e0e237537be
Publikováno v:
EJNMMI Research, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Background Hyperpolarization enhances the sensitivity of nuclear magnetic resonance experiments by between four and five orders of magnitude. Several hyperpolarized sensor molecules have been introduced that enable high sensitivity detection
Externí odkaz:
https://doaj.org/article/5956e60d0eeb4c8cb5bfafe6b99e0d42
Autor:
Jason G. Skinner, Geoffrey J. Topping, Luca Nagel, Irina Heid, Christian Hundshammer, Martin Grashei, Frits H. A. van Heijster, Rickmer Braren, Franz Schilling
Publikováno v:
Magnetic Resonance in Medicine.
Autor:
Geoffrey J. Topping, Irina Heid, Marija Trajkovic-Arsic, Lukas Kritzner, Martin Grashei, Christian Hundshammer, Maximilian Aigner, Jason G. Skinner, Rickmer Braren, Franz Schilling
Publikováno v:
Biomedicines, Vol 9, Iss 2, p 121 (2021)
Hyperpolarized 13C nuclear magnetic resonance spectroscopy can characterize in vivo tissue metabolism, including preclinical models of cancer and inflammatory disease. Broad bandwidth radiofrequency excitation is often paired with free induction deca
Externí odkaz:
https://doaj.org/article/e87b3e143df74a7d8c3003f4665b8ebf
Autor:
Markus Schwaiger, Dominik von Elverfeldt, Sven Månsson, Stephan Berner, Miriam Braeuer, Christoph A. Müller, Jason G. Skinner, Jochen Leupold, Jan-Bernd Hövener, Stephan Düwel, Adam E. Hansen, Jan Henrik Ardenkjær-Larsen, Franz Schilling, Jürgen Hennig, Stephan G. Nekolla, Christian Hundshammer
Publikováno v:
NMR in Biomedicine
Müller, C A, Hundshammer, C, Braeuer, M, Skinner, J G, Berner, S, Leupold, J, Düwel, S, Nekolla, S G, Månsson, S, Hansen, A E, von Elverfeldt, D, Ardenkjaer-Larsen, J H, Schilling, F, Schwaiger, M, Hennig, J & Hövener, J-B 2020, ' Dynamic 2D and 3D mapping of hyperpolarized pyruvate to lactate conversion in vivo with efficient multi-echo balanced steady-state free precession at 3 T ', NMR in Biomedicine, vol. 33, no. 6, e4291 . https://doi.org/10.1002/nbm.4291
Müller, C A, Hundshammer, C, Braeuer, M, Skinner, J G, Berner, S, Leupold, J, Düwel, S, Nekolla, S G, Månsson, S, Hansen, A E, von Elverfeldt, D, Ardenkjaer-Larsen, J H, Schilling, F, Schwaiger, M, Hennig, J & Hövener, J B 2020, ' Dynamic 2D and 3D mapping of hyperpolarized pyruvate to lactate conversion in vivo with efficient multi-echo balanced steady-state free precession at 3 T ', NMR in Biomedicine, vol. 33, no. 6, e4291 . https://doi.org/10.1002/nbm.4291
Müller, C A, Hundshammer, C, Braeuer, M, Skinner, J G, Berner, S, Leupold, J, Düwel, S, Nekolla, S G, Månsson, S, Hansen, A E, von Elverfeldt, D, Ardenkjaer-Larsen, J H, Schilling, F, Schwaiger, M, Hennig, J & Hövener, J-B 2020, ' Dynamic 2D and 3D mapping of hyperpolarized pyruvate to lactate conversion in vivo with efficient multi-echo balanced steady-state free precession at 3 T ', NMR in Biomedicine, vol. 33, no. 6, e4291 . https://doi.org/10.1002/nbm.4291
Müller, C A, Hundshammer, C, Braeuer, M, Skinner, J G, Berner, S, Leupold, J, Düwel, S, Nekolla, S G, Månsson, S, Hansen, A E, von Elverfeldt, D, Ardenkjaer-Larsen, J H, Schilling, F, Schwaiger, M, Hennig, J & Hövener, J B 2020, ' Dynamic 2D and 3D mapping of hyperpolarized pyruvate to lactate conversion in vivo with efficient multi-echo balanced steady-state free precession at 3 T ', NMR in Biomedicine, vol. 33, no. 6, e4291 . https://doi.org/10.1002/nbm.4291
The aim of this study was to acquire the transient MRI signal of hyperpolarized tracers and their metabolites efficiently, for which specialized imaging sequences are required. In this work, a multi-echo balanced steady-state free precession (me-bSSF
Autor:
Maximilian Aigner, Rolf F. Schulte, Geoffrey J. Topping, Christian Hundshammer, Franz Schilling, Martin Grashei, Luca Nagel, Jason G. Skinner
Publikováno v:
Magnetic Resonance Materials in Physics, Biology and Medicine
Magma (New York, N.y.)
Magma (New York, N.y.)
Hyperpolarization is an emerging method in magnetic resonance imaging that allows nuclear spin polarization of gases or liquids to be temporarily enhanced by up to five or six orders of magnitude at clinically relevant field strengths and administere
Autor:
Sonja Tattermusch, Jason A Skinner, Damien Chaussabel, Jacques Banchereau, Matthew P Berry, Finlay W McNab, Anne O'Garra, Graham P Taylor, Charles R M Bangham
Publikováno v:
PLoS Pathogens, Vol 8, Iss 1, p e1002480 (2012)
Human T-lymphotropic virus type 1 (HTLV-1) is a retrovirus that persists lifelong in the host. In ∼4% of infected people, HTLV-1 causes a chronic disabling neuroinflammatory disease known as HTLV-1-associated myelopathy/tropical spastic paraparesis
Externí odkaz:
https://doaj.org/article/9568bf840c1c48c092a25eeccf3a9c12
Autor:
Kaili Ranta, Eduard Y. Chekmenev, Panayiotis Nikolaou, Aaron M. Coffey, Boyd M. Goodson, Michael J. Barlow, Jason G. Skinner, Nicholas Whiting, Matthew S. Rosen, Peter G. Morris
Publikováno v:
J Magn Reson
© 2020 Elsevier Inc. Spin-exchange optical pumping (SEOP) can enhance the NMR sensitivity of noble gases by up to five orders of magnitude at Tesla-strength magnetic fields. SEOP-generated hyperpolarised (HP) 129Xe is a promising contrast agent for
Autor:
Bobby Lanier, Jacob Cardenas, Sangkon Oh, Jacob Turner, HyeMee Joo, Durgha Nattami, Mark Millard, Katherine Upchurch, Matthew Wiest, Jason A. Skinner
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical ImmunologyREFERENCES. 50(9)
BACKGROUND Anti-IgE (omalizumab) has been used for the treatment of moderate-to-severe asthma that is not controlled by inhaled steroids. Despite its success, it does not always provide patients with significant clinical benefits. OBJECTIVE To invest
Autor:
Alessandra Flori, Jason G. Skinner, Anna Dost, Luca Menichetti, Markus Plaumann, Ferdia Gallagher, Jan-Bernd Hövener, Andreas B. Schmidt
Publikováno v:
Molecular Imaging and Biology
Since reaching the clinic, magnetic resonance imaging (MRI) has become an irreplaceable radiological tool because of the macroscopic information it provides across almost all organs and soft tissues within the human body, all without the need for ion