Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Jason A. Rech"'
Autor:
Bartosz P. Grudzinski, Ken Fritz, Heather E. Golden, Tammy A. Newcomer-Johnson, Jason A. Rech, Jonathan Levy, Justin Fain, Jessica L. McCarty, Brent Johnson, Teng Keng Vang, Karsten Maurer
Publikováno v:
Global Ecology and Conservation, Vol 37, Iss , Pp e02163- (2022)
Beaver are recolonizing previously occupied regions, expanding into new territories, and increasingly being introduced and protected for stream conservation and restoration across numerous biomes. However, beaver dam effects on the physical, chemical
Externí odkaz:
https://doaj.org/article/0a669ce2e6824946aed97d9245b8256c
Autor:
Thomas J. Wubben, Sraboni Chaudhury, Brennan T. Watch, Jeanne A. Stuckey, Eric Weh, Roshini Fernando, Moloy Goswami, Mercy Pawar, Jason C. Rech, Cagri G. Besirli
Publikováno v:
Pharmaceuticals, Vol 16, Iss 5, p 705 (2023)
Treatment options are lacking to prevent photoreceptor death and subsequent vision loss. Previously, we demonstrated that reprogramming metabolism via the pharmacologic activation of PKM2 is a novel photoreceptor neuroprotective strategy. However, th
Externí odkaz:
https://doaj.org/article/7124d30a36fa4bc784f3b67ee9fb35b2
Autor:
Chao-Yie Yang, Xinrui Yuan, Hua Jiang, Jason C. Rech, Denggang Fu, Aaron Robida, Krishani Rajanayake, Hebao Yuan, Bo Wen, Duxin Sun, Krishnapriya Chinnaswamy, Jeanne A. Stuckey, Sophie Paczesny
Publikováno v:
Blood. 140:10675-10677
Autor:
Jeffrey C. Nekola, Jason A. Rech, Kathleen B. Springer, Yurena Yanes, Stephanie Bosch, Jeffrey S. Pigati
Publikováno v:
Quaternary Research. 104:43-53
Recent studies have shown the oxygen isotopic composition (δ18O) of modern terrestrial gastropod shells is determined largely by the δ18O of precipitation. This implies that fossil shells could be used to reconstruct the δ18O of paleo-precipitatio
Autor:
Jason C. Rech, Bruce L. Grasberger, Michael A. Letavic, Jinquan Luo, Changlu Liu, Jichun Ma, Michael P. Maher, Renee L. DesJarlais, Jeffrey Schoellerman, Rebecca Hagan, Yi Liu, Robyn L. Miller, David Lin
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications Biology
Communications Biology
Acid-sensing ion channels (ASICs) are proton-gated cation channels critical for neuronal functions. Studies of ASIC1, a major ASIC isoform and proton sensor, have identified acidic pocket, an extracellular region enriched in acidic residues, as a key
Autor:
Xinrui Yuan, Hua Jiang, Denggang Fu, Aaron Robida, Krishani Rajanayake, Hebao Yuan, Bo Wen, Duxin Sun, Brennan T. Watch, Krishnapriya Chinnaswamy, Jeanne A. Stuckey, Sophie Paczesny, Jason C. Rech, Chao-Yie Yang
Publikováno v:
SSRN Electronic Journal.
Autor:
Akinola Soyode-Johnson, Michael A. Letavic, Kevin J. Coe, Christa C. Chrovian, Brian Lord, Nicholas I. Carruthers, Wall Jessica L, Bartosz Balana, Xiaohui Jiang, Tatiana Koudriakova, Leslie Nguyen, Jason C. Rech, Jeff Schoellerman
Publikováno v:
ACS Medicinal Chemistry Letters. 10:261-266
Herein, we disclose a series of selective GluN2B negative allosteric modulators containing a 1H-pyrrolo[3,2-b]pyridine core. Lead optimization efforts included increasing brain penetration as well as decreasing cytochrome P450 inhibition and hERG cha
Autor:
Rodrigo Riquelme, Shanying Li, Naomi E. Kirk-Lawlor, Teresa E. Jordan, Jared T. Gooley, Brian S. Currie, Jason A. Rech, Sophie B. Lehmann
Publikováno v:
Earth and Planetary Science Letters. 506:184-194
The Central Andes of South America are one of the highest and broadest mountain ranges on earth and have a profound influence on climate in the Southern Hemisphere. Yet, the timing of Andean uplift and its subsequent impact on atmospheric circulation
Autor:
Calogero M. Santoro, José M. Capriles, Jason A. Rech, T. Race Workman, Claudio Latorre, Craig David Tully, Eugenia M. Gayo
Publikováno v:
Quaternary Research. 91:63-80
A key concern regarding current and future climate change is the possibility of sustained droughts that can have profound impacts on societies. As such, multiple paleoclimatic proxies are needed to identify megadroughts, the synoptic climatology resp
Autor:
Jeffrey S. Pigati, J. P. Dodd, Jason A. Rech, Nasser M. Al-Qattan, Jeffrey C. Nekola, Yurena Yanes
Publikováno v:
Quaternary Research. 91:329-344
Continental paleoclimate proxies with near-global coverage are rare. Land snail δ18O is one of the few proxies abundant in Quaternary sediments ranging from the tropics to the high Arctic tundra. However, its application in paleoclimatology remains