Zobrazeno 1 - 10
of 351
pro vyhledávání: '"Jason A. Park"'
Autor:
Hong Mu-Mosley, Mitchell S. von Itzstein, Farjana Fattah, Jialiang Liu, Chengsong Zhu, Yang Xie, Edward K. Wakeland, Jason Y. Park, Brad S. Kahl, Catherine S. Diefenbach, David E. Gerber
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTImmune checkpoint inhibitors (ICI) are increasingly used in combination. To understand the effects of different ICI categories, we characterized changes in circulating autoantibodies in patients enrolled in the E4412 trial (NCT01896999) of br
Externí odkaz:
https://doaj.org/article/51d24a432465425b8ddda0a091d602da
Autor:
Dhavamani Sugasini, Jason C. Park, J. Jason McAnany, Tae-Hoon Kim, Guangying Ma, Xincheng Yao, Babu Antharavally, Anil Oroskar, Asha A. Oroskar, Brian T. Layden, Papasani V. Subbaiah
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Alzheimer disease (AD) is the most prevalent cause of dementia in the elderly. Although impaired cognition and memory are the most prominent features of AD, abnormalities in visual functions often precede them, and are increasingly being use
Externí odkaz:
https://doaj.org/article/b0f8746686a34e1289bf3e014810371d
Autor:
Adrian Avila, Ignacio Málaga, Deepa Sirsi, Saima Kayani, Sharon Primeaux, Gauri A. Kathote, Vikram Jakkamsetti, Raja Reddy Kallem, William C. Putnam, Jason Y. Park, Shlomo Shinnar, Juan M. Pascual
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Fuel influx and metabolism replenish carbon lost during normal neural activity. Ketogenic diets studied in epilepsy, dementia and other disorders do not sustain such replenishment because their ketone body derivatives contain four carbon ato
Externí odkaz:
https://doaj.org/article/cad7acfea0c04d9181199beb577e7f81
Autor:
Abhinav Thummala, Rhea Sudhakaran, Anoop Gurram, Jacqueline Mersch, Alexa Badalamenti, Garrett Gottaway, Jason Y. Park, Jeffrey A. Sorelle, Sukh Makhnoon
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 101867- (2024)
Purpose: A primary challenge in clinical genetics is accurate interpretation of identified variants and relaying the information to patients and providers. Inconsistencies around handling variant reclassifications and notifying patients, combined wit
Externí odkaz:
https://doaj.org/article/d9bc88f3adf548ebba681344998acf47
Autor:
Jason C. Park, Oksana Persidina, Giri Balasubramanian, Tara Nguyen, Anubhav Pradeep, John R. Hetling, J. Jason McAnany
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Changes in the full-field flash and flicker electroretinogram (ERG) that accompany normal aging were evaluated in mice. ERGs were recorded from a single cohort of C57BL/6J mice from 5 to 70 weeks of age using conventional techniques. Dark-ad
Externí odkaz:
https://doaj.org/article/1e6665774ffb448ba76ae4f89061990f
Autor:
Ladan Agharokh, Katherine Mamola, Andrew G. Yu, Annette L. Medina, Bhaskar Gurram, Julie Fuller, Jason Y. Park, Weina Chen, Veena Rajaram, Matthew R. Hammer, Jeff L. Waugh
Publikováno v:
Journal of Medical Case Reports, Vol 17, Iss 1, Pp 1-7 (2023)
Abstract Background Inflammatory bowel disease is an inflammatory disorder that primarily impacts the gastrointestinal tract, leading to malnutrition and chronic microscopic intestinal blood loss. Uncontrolled systemic inflammation can impact other p
Externí odkaz:
https://doaj.org/article/097b3b650a8e4750bbc9c85391ad96e1
Autor:
Ignacio Málaga, Adrian Avila, Sharon Primeaux, Raja Reddy Kallem, Charles R. Roe, William C. Putnam, Jason Y. Park, Shlomo Shinnar, Chul Ahn, Juan M. Pascual
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Augmentation of anaplerosis, or replenishment of carbon lost during intermediary metabolic transitions, is desirable in energy metabolism defects. Triheptanoin, the triglyceride of 7-carbon heptanoic acid, is anaplerotic via direct oxidation
Externí odkaz:
https://doaj.org/article/0eda3791dde24b34a03d79eca26f7f88
Autor:
Jason M. Park, Brittany M. Genera, Deirdre Fahy, Kyle T. Swallow, Curtis M. Nelson, Jonathan D. Oliver, Dana K. Shaw, Ulrike G. Munderloh, Kelly A. Brayton
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Pathogens must adapt to disparate environments in permissive host species, a feat that is especially pronounced for vector-borne microbes, which transition between vertebrate hosts and arthropod vectors to complete their lifecycles. Most kno
Externí odkaz:
https://doaj.org/article/5791de239c8848dda4561cb257461ef9
Autor:
Kristin L. Rosche, Joanna Hurtado, Elis A. Fisk, Kaylee A. Vosbigian, Ashley L. Warren, Lindsay C. Sidak-Loftis, Sarah J. Wright, Elisabeth Ramirez-Zepp, Jason M. Park, Dana K. Shaw
Publikováno v:
mSphere, Vol 8, Iss 5 (2023)
ABSTRACT A crucial phase in the life cycle of tick-borne pathogens is the time spent colonizing and persisting within the arthropod. Tick immunity is emerging as a key force shaping how transmissible pathogens interact with the vector. How pathogens
Externí odkaz:
https://doaj.org/article/ab818690846f407d9a0cf16c91342663
Autor:
Yang Xie, Shaheen Khan, Prithvi Raj, Edward K Wakeland, Mitchell S von Itzstein, Farjana Fattah, Jason Y Park, David Hsiehchen, Jared Ostmeyer, David E Gerber, Mary Gwin, Rodrigo Catalan
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 8 (2023)
Background Immune checkpoint inhibitor (ICI) therapies may cause unpredictable and potentially severe autoimmune toxicities termed immune-related adverse events (irAEs). Because T cells mediate ICI effects, T cell profiling may provide insight into t
Externí odkaz:
https://doaj.org/article/3479b528102c43d8a55d222dbb9e00ea