Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jason A. Luther"'
Autor:
Jason W Luther, Patrick Williams
Publikováno v:
SoundEffects, Vol 9, Iss 1 (2020)
While participatory culture has been of special interest to scholars for nearly three decades, much of the focus has centered on digitally networked contexts. The digital age has indeed transformed our approaches to listening to music and how we oper
Externí odkaz:
https://doaj.org/article/9677cddf49e1426981d5f543ac42f071
Autor:
Kristin Taborn, Joseph Ligutti, Josie H. Lee, Thomas Kornecook, Dong Liu, Dawn Zhu, Stephen Altmann, Ruoyuan Yin, Xuhai Be, Robert T. Fremeau, Jinti Wang, John Roberts, David J. Matson, Danielle Johnson, Violeta Yu, Christopher P Ilch, Bryan D. Moyer, Jason A. Luther, Virginia Berry, Matthew Weiss, Danny Ortuno, Michael Jarosh, Sonya G. Lehto
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 362:146-160
Potent and selective antagonists of the voltage-gated sodium channel NaV1.7 represent a promising avenue for the development of new chronic pain therapies. We generated a small molecule atropisomer quinolone sulfonamide antagonist AMG8379 and a less
Autor:
Shuyan Yi, Sonya G. Lehto, Stefan I. McDonough, Klaus Michelsen, Erin F. DiMauro, Hao Chen, Maosheng Zhang, Stephen Schneider, Shawn Ayube, Jason A. Luther, Matthew H. Plant, Xin Huang, David J. Matson, Jeffrey R. Simard, Howard Bregman, Jacinthe Gingras, Paul L. Shaffer, Yohannes Teffera
Publikováno v:
Nature Structural & Molecular Biology. 24:108-113
Current therapies to treat persistent pain and neuropathic pain are limited by poor efficacy, side effects and risk of addiction. Here, we present a novel class of potent selective, central nervous system (CNS)-penetrant potentiators of glycine recep
Publikováno v:
Journal of Neurophysiology. 109:485-496
The sympathetic nervous system regulates many essential physiological systems, and its dysfunction is implicated in cardiovascular diseases. Mechanisms that control the strength of sympathetic output are therefore potential targets for the management
Autor:
Susan J. Birren, Jason A. Luther
Publikováno v:
Autonomic Neuroscience. 151:46-60
The electrical and synaptic properties of neurons are essential for determining the function of the nervous system. Thus, understanding the mechanisms that control the appropriate developmental acquisition and maintenance of these properties is a cri
Autor:
Susan J. Birren, Jason A. Luther
Publikováno v:
The Journal of Neuroscience. 29:5411-5424
Neurotrophins such as nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) act through the tropomyosin-related receptor tyrosine kinases (Trk) and the pan-neurotrophin receptor (p75) to regulate complex developmental and functional
Autor:
Jason W Luther
Publikováno v:
Community Literacy Journal. 9
Publikováno v:
Developmental neurobiology. 70(14)
Recent evidence has demonstrated that cotransmission from mammalian neurons is not uniquely achieved by costorage and corelease of transmitters and cotransmitters from single varicosities, but also by the concurrent release of mediators segregated in
Autor:
Jason A. Luther, Susan J. Birren
Publikováno v:
Co-Existence and Co-Release of Classical Neurotransmitters ISBN: 9780387096216
Neurotransmitter expression has long been thought of as a defining phenotypic property of adult neurons. However, it has now been shown that most neurons co-release multiple signaling molecules. Many examples of neurons that co-release a classical tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4064aa1ef18f5aa19cfe17870237a05
https://doi.org/10.1007/978-0-387-09622-3_4
https://doi.org/10.1007/978-0-387-09622-3_4
Autor:
Susan J. Birren, Jason A. Luther
Publikováno v:
Journal of neurophysiology. 96(2)
The sympathetic nervous system is an essential regulator of the cardiovascular system and interactions with target tissue regulate sympathetic neuronal properties. The heart produces nerve growth factor (NGF), which promotes sympathetic noradrenergic