Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jason A. Liao"'
Autor:
Evan P. Taddeo, Stefan R. Hargett, Sujoy Lahiri, Marin E. Nelson, Jason A. Liao, Chien Li, Jill K. Slack-Davis, Jose L. Tomsig, Kevin R. Lynch, Zhen Yan, Thurl E. Harris, Kyle L. Hoehn
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Hepatic glucose production (HGP) is required to maintain normoglycemia during fasting. Glucagon is the primary hormone responsible for increasing HGP; however, there are many additional hormone and metabolic factors that influence glucagon s
Externí odkaz:
https://doaj.org/article/e280b7810e98472f94e89b5b849f2537
Publikováno v:
Contemporary Clinical Trials Communications, Vol 40, Iss , Pp 101329- (2024)
Background: Traditional dose selection for oncology registration trials typically employs a one- or two-step single maximum tolerated dose (MTD) approach. However, this approach may not be appropriate for molecularly targeted therapy, which tends to
Externí odkaz:
https://doaj.org/article/cf6b9d3798e44c5bb59d9d76b7beb11d
Autor:
Paul Lee, Rita Yim, Kai-Kei Miu, Sin-Hang Fung, Jason Jinyue Liao, Zhangting Wang, Jun Li, Yammy Yung, Hiu-Tung Chu, Pui-Kwan Yip, Emily Lee, Eric Tse, Yok-Lam Kwong, Harinder Gill
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 10; Pages: 5670
In myelodysplastic syndrome (MDS), resistance to hypomethylating agents (HMA) portends a poor prognosis, underscoring the importance of understanding the molecular mechanisms leading to HMA-resistance. In this study, P39 and Kasumi-1 cells and their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c00621a25e2440a63aaa02b16a85bae
Autor:
Paul, Lee, Rita, Yim, Kai-Kei, Miu, Sin-Hang, Fung, Jason Jinyue, Liao, Zhangting, Wang, Jun, Li, Yammy, Yung, Hiu-Tung, Chu, Pui-Kwan, Yip, Emily, Lee, Eric, Tse, Yok-Lam, Kwong, Harinder, Gill
Publikováno v:
International journal of molecular sciences. 23(10)
In myelodysplastic syndrome (MDS), resistance to hypomethylating agents (HMA) portends a poor prognosis, underscoring the importance of understanding the molecular mechanisms leading to HMA-resistance. In this study, P39 and Kasumi-1 cells and their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e4a581a8a4a8095b34a37ca87f5b0ca3
https://pubmed.ncbi.nlm.nih.gov/35628480
https://pubmed.ncbi.nlm.nih.gov/35628480
Publikováno v:
Simultaneous Global New Drug Development ISBN: 9781003109785
Simultaneous Global New Drug Development
Simultaneous Global New Drug Development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a19b9256d60029208ade34833f128ff9
https://doi.org/10.1201/9781003109785-19
https://doi.org/10.1201/9781003109785-19
Publikováno v:
Cornea. 36(6)
To investigate the collagen and elastin architecture at the junction of the human cornea and trabecular meshwork (TM).The cornea, TM, and ciliary body (CB) tendons of unfixed human corneal buttons were imaged with an inverted 2-photon excited fluores
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::566d0aaaeeb43af426a848f837e2126a
https://pubmed.ncbi.nlm.nih.gov/28368994
https://pubmed.ncbi.nlm.nih.gov/28368994
Publikováno v:
Journal of Biometrics & Biostatistics.
It is often interest of comparing two pharmacodynamics (PD) profiles in drug development. Currently the common practice is borrowing the bioequivalence (BE) rule in pharmacokinetics analysis for pharmacodynamics comparison in terms of the area under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::caa057040ed3d391d8b34c618c8ac5ec
https://doi.org/10.4172/2155-6180.1000345
https://doi.org/10.4172/2155-6180.1000345
Autor:
Kyle L. Hoehn, Brandon M. Kenwood, Valeria R. Mas, Robert T. Lawrence, David S. Breen, Frances L. Byrne, Gregory J. Cooney, Pere Puigserver, David E. James, Stephen H. Caldwell, Jenny D.Y. Chow, Jason A. Liao, Carolin Lackner, Saeko Okutsu, Jose L. Tomsig, John E. Dominy, Marin E. Healy, Nigel Turner, Judit Villén
Publikováno v:
Molecular Metabolism
Lipid deposition in the liver is associated with metabolic disorders including fatty liver disease, type II diabetes, and hepatocellular cancer. The enzymes acetyl-CoA carboxylase 1 (ACC1) and ACC2 are powerful regulators of hepatic fat storage; ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca70e11ed4a6959c6daa0ea970c9f9a3
https://doi.org/10.1016/j.molmet.2014.02.004
https://doi.org/10.1016/j.molmet.2014.02.004
Autor:
Choul Yong Park, Ji-won Kwon, Jason A. Liao, Jimmy K. Lee, Roy S. Chuck, Catherine M. Marando
Publikováno v:
Investigative ophthalmologyvisual science. 57(13)
Purpose To investigate the architecture and distribution of collagen and elastin in human limbal conjunctiva, Tenon's capsule, and sclera. Methods The limbal conjunctiva, Tenon's capsule, and sclera of human donor corneal buttons were imaged with an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c7a5151ec1e394502ea3165669b693
https://pubmed.ncbi.nlm.nih.gov/27784064
https://pubmed.ncbi.nlm.nih.gov/27784064
Autor:
Kevin R. Lynch, Jose L. Tomsig, Zhen Yan, Stefan R. Hargett, Evan P. Taddeo, Kyle L. Hoehn, Marin E. Nelson, Jason A. Liao, Sujoy Lahiri, Chien Li, Jill K. Slack-Davis, Thurl E. Harris
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Hepatic glucose production (HGP) is required to maintain normoglycemia during fasting. Glucagon is the primary hormone responsible for increasing HGP; however, there are many additional hormone and metabolic factors that influence glucagon sensitivit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7c1e8f2a261a0c46f2d726ea6f7c105
https://pubmed.ncbi.nlm.nih.gov/28273928
https://pubmed.ncbi.nlm.nih.gov/28273928