Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Jason A. King"'
Autor:
Israel Kiiza Njovu, Pauline Petra Nalumaga, Lucas Ampaire, Edwin Nuwagira, James Mwesigye, Benson Musinguzi, Kennedy Kassaza, Kabanda Taseera, James Kiguli Mukasa, Joel Bazira, Jacob Stanley Iramiot, Andrew Baguma, Felix Bongomin, Richard Kwizera, Beatrice Achan, Michael J Cox, Jason S King, Robin May, Elizabeth R Ballou, Herbert Itabangi
Publikováno v:
JMIR Research Protocols, Vol 12, p e48014 (2023)
BackgroundFungal-bacterial cocolonization and coinfections pose an emerging challenge among patients suspected of having pulmonary tuberculosis (PTB); however, the underlying pathogenic mechanisms and microbiome interactions are poorly understood. Un
Externí odkaz:
https://doaj.org/article/fa0c2c8e627a4ba6a4ab13720d7fa50c
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Engineering E. coli for metabolization of methanol to produce fuels and chemicals has not been fully achieved. Here, the authors combine metabolic engineering and chemical inhibition to improve methanol assimilation and distinguish the role of kineti
Externí odkaz:
https://doaj.org/article/60acd311edfb421fb3ff1741090fb9a0
Autor:
Robin S. B. Williams, Jonathan R. Chubb, Robert Insall, Jason S. King, Catherine J. Pears, Elinor Thompson, Cornelis J. Weijer
Publikováno v:
Cells, Vol 10, Iss 11, p 3036 (2021)
The social amoeba Dictyostelium discoideum provides an excellent model for research across a broad range of disciplines within biology. The organism diverged from the plant, yeast, fungi and animal kingdoms around 1 billion years ago but retains comm
Externí odkaz:
https://doaj.org/article/f2b596d9ab964d1abd26f5afb1f293c3
Autor:
Catherine M Buckley, Victoria L Heath, Aurélie Guého, Cristina Bosmani, Paulina Knobloch, Phumzile Sikakana, Nicolas Personnic, Stephen K Dove, Robert H Michell, Roger Meier, Hubert Hilbi, Thierry Soldati, Robert H Insall, Jason S King
Publikováno v:
PLoS Pathogens, Vol 15, Iss 2, p e1007551 (2019)
By engulfing potentially harmful microbes, professional phagocytes are continually at risk from intracellular pathogens. To avoid becoming infected, the host must kill pathogens in the phagosome before they can escape or establish a survival niche. H
Externí odkaz:
https://doaj.org/article/1c14a090b71c476d9af92603e842ac01
Publikováno v:
Journal of Biomedical Optics. 28
Publikováno v:
Molecular biology of the cell.
Katnip is a highly conserved gene found mutated in some ciliopathies. In Dictyostelium, Katnip plays a general role in microtubule regulation and is required for lysosomal trafficking and digestion of autophagosomes and phagosomes.
Autor:
Ana T López-Jiménez, Elena Cardenal-Muñoz, Florence Leuba, Lilli Gerstenmaier, Caroline Barisch, Monica Hagedorn, Jason S King, Thierry Soldati
Publikováno v:
PLoS Pathogens, Vol 14, Iss 12, p e1007501 (2018)
Phagocytic cells capture and kill most invader microbes within the bactericidal phagosome, but some pathogens subvert killing by damaging the compartment and escaping to the cytosol. To prevent the leakage of pathogen virulence and host defence facto
Externí odkaz:
https://doaj.org/article/38e2e813fd284008adff457f66458ec9
Autor:
Rhys A. Watkins, Alexandre Andrews, Charlotte Wynn, Caroline Barisch, Jason S. King, Simon A. Johnston
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Cryptococcus neoformans is an environmental yeast that can cause opportunistic infections in humans. As infecting animals does not form part of its normal life-cycle, it has been proposed that the virulence traits that allow cryptococci to resist imm
Externí odkaz:
https://doaj.org/article/da1ff1fc9a3249a8909e2adea9045c2a
Autor:
Chenfei Gao, Michael L. King, Zachary L. Fitzpatrick, Wenqian Wei, Jason F. King, Mingming Wang, Frank L. Greenway, John W. Finley, Jeffrey H. Burton, William D. Johnson, Michael J. Keenan, Frederick M. Enright, Roy J. Martin, Jolene Zheng
Publikováno v:
Journal of Functional Foods, Vol 18, Iss , Pp 564-574 (2015)
Prowashonupana barley (PWB) is high in β-glucan with moderate content of resistant starch. PWB reduced intestinal fat deposition (IFD) in wild type Caenorhabditis elegans (C. elegans, N2), and in sir-2.1 or daf-16 null mutants, and sustained a surro
Externí odkaz:
https://doaj.org/article/13fcd0695dbd4db5953ae9f71f294fd3
Autor:
Judith E. Lutton, Helena L. E. Coker, Peggy Paschke, Christopher J. Munn, Jason S. King, Till Bretschneider, Robert R. Kay
Macropinocytosis is a conserved endocytic process where cells take up medium into micron-sized vesicles. InDictyostelium, macropinocytic cups form around domains of PIP3 in the plasma membrane and extend by actin polymerization. Using lattice light-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::610a803af9e5e9e37885863d2952b527
https://doi.org/10.1101/2022.10.07.511330
https://doi.org/10.1101/2022.10.07.511330