Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jason A. Witek"'
Autor:
Jason A. Witek, Allen F. Brooks, Sahil M. Kapila, Wade P. Winton, Jenelle R. Stauff, Peter J. H. Scott, Benjamin L. Viglianti
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 833 (2024)
Background: Cancer-associated fibroblasts have become a new target for therapy. Fibroblasts present within malignancies express the fibroblast activation protein (FAP). Inhibitors to FAP (FAPI) are small molecules recently developed as a theranostic
Externí odkaz:
https://doaj.org/article/888a280618324ad0a19e69fffa3795ff
Publikováno v:
ACS chemical neuroscience. 13(19)
Imaging of misfolded proteins implicated in neurodegenerative disorders using positron emission tomography (PET) imaging has revolutionized dementia research. In this viewpoint, the development of radiotracers for tau PET is highlighted. We draw atte
Publikováno v:
Tetrahedron. 67:8229-8234
Intermolecular Michael-type conjugate additions of some in situ-generated ring-substituted nitrosocyclohexenes with both carbon- and heteronucleophiles have been found to be highly stereoselective, leading predominantly (or exclusively) to products r
Publikováno v:
Tetrahedron Letters. 51:2032-2035
A diverse array of nitrosoalkenes derived from both acyclic and cyclic ketones, as well as aldehydes, via the Denmark protocol using alpha-chloro-O-TBS-oximes can be trapped efficiently in situ by a wide variety of potassium ester enolates to afford
Publikováno v:
Tetrahedron Letters. 51:3555-3557
A wide array of readily prepared pivalates of ketoximes can be converted to the corresponding ketones in good yields by treatment with iron powder in THF containing catalytic amounts of both trimethylsilyl chloride and glacial acetic acid at room tem
Autor:
Witek, Jason A.1 (AUTHOR) kilsoo@umich.edu, Brooks, Allen F.1 (AUTHOR) afb@umich.edu, Kapila, Sahil M.2 (AUTHOR) smkapila@umich.edu, Winton, Wade P.1 (AUTHOR) jrstauff@med.umich.edu, Stauff, Jenelle R.1 (AUTHOR) pjhscott@med.umich.edu, Scott, Peter J. H.1,3 (AUTHOR), Viglianti, Benjamin L.1 (AUTHOR) afb@umich.edu
Publikováno v:
Pharmaceuticals (14248247). Jul2024, Vol. 17 Issue 7, p833. 11p.
Publikováno v:
ChemInform. 41
A diverse array of nitrosoalkenes derived from both acyclic and cyclic ketones, as well as aldehydes, via the Denmark protocol using α-chloro-O-TBS-oximes can be trapped efficiently in situ by a wide variety of potassium ester enolates to afford con
Autor:
Jason A. Witek, Steven M. Weinreb
Publikováno v:
Organic Letters; Mar2011, Vol. 13 Issue 5, p1258-1260, 3p
Publikováno v:
Journal of Risk & Financial Management; Oct2022, Vol. 15 Issue 10, p434-N.PAG, 14p