Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Jason A Steen"'
Autor:
Heidi Fettke, Jason A Steen, Edmond M Kwan, Patricia Bukczynska, Shivakumar Keerthikumar, David Goode, Maria Docanto, Nicole Ng, Luciano Martelotto, Christine Hauser, Melissa C Southey, Arun A Azad, Tu Nguyen-Dumont
Publikováno v:
BioTechniques, Vol 69, Iss 2, Pp 133-140 (2020)
Plasma circulating tumor DNA (ctDNA) analysis has emerged as a minimally invasive means to perform molecular tumor typing. Here we developed a custom ultra-sensitive ctDNA next-generation sequencing assay using molecular barcoding technology and off-
Externí odkaz:
https://doaj.org/article/426ccb7d425e4c5d9137c70096bb5e8a
Autor:
Björn A Espedido, Jason A Steen, Helen Ziochos, Sean M Grimmond, Matthew A Cooper, Iain B Gosbell, Sebastiaan J van Hal, Slade O Jensen
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59920 (2013)
Whole genome sequencing was used to characterize the resistome of intensive care unit (ICU) outbreak-associated carbapenem-resistant K. pneumoniae isolates. Importantly, and of particular concern, the carbapenem-hydrolyzing β-lactamase gene bla(OXA-
Externí odkaz:
https://doaj.org/article/03e7f515390c46dc835c71489162f097
Autor:
Yogitha N Srikhanta, Rebecca J Gorrell, Jason A Steen, Jayde A Gawthorne, Terry Kwok, Sean M Grimmond, Roy M Robins-Browne, Michael P Jennings
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e27569 (2011)
Many host-adapted bacterial pathogens contain DNA methyltransferases (mod genes) that are subject to phase-variable expression (high-frequency reversible ON/OFF switching of gene expression). In Haemophilus influenzae and pathogenic Neisseria, the ra
Externí odkaz:
https://doaj.org/article/10a05969ff9a4e6fb4c611f41657e2d3
Autor:
Jason A Steen, Jennifer A Steen, Paul Harrison, Torsten Seemann, Ian Wilkie, Marina Harper, Ben Adler, John D Boyce
Publikováno v:
PLoS Pathogens, Vol 6, Iss 2, p e1000750 (2010)
P. multocida is the causative agent of a wide range of diseases of animals, including fowl cholera in poultry and wild birds. Fowl cholera isolates of P. multocida generally express a capsular polysaccharide composed of hyaluronic acid. There have be
Externí odkaz:
https://doaj.org/article/ca99b6d0d0314661a48626dd8a7bcce1
Autor:
Anne-Laure Renault, James G. Dowty, Jason A. Steen, Shuai Li, Ingrid M. Winship, Graham G. Giles, John L. Hopper, Melissa C. Southey, Tú Nguyen-Dumont
Publikováno v:
Breast Cancer Research, Vol 24, Iss 1, Pp 1-6 (2022)
Abstract Background Multigene panel tests for breast cancer predisposition routinely include ATM as it is now a well-established breast cancer predisposition gene. Methods We included ATM in a multigene panel test applied to the Australian Breast Can
Externí odkaz:
https://doaj.org/article/b587e9aeae7c48c2bef8c3aebeb0aa2a
Autor:
Maria Docanto, Christine Hauser, Edmond M. Kwan, Nicole Ng, Jason A. Steen, Siavash Foroughi, Melissa C. Southey, Arun Azad, Phillip Parente, Heidi Fettke, Carmel Pezaro, Patricia Bukczynska, Andrew Mant, Tu Nguyen-Dumont
Publikováno v:
The Prostate. 81:992-1001
Background The androgen receptor (AR) pathway-associated gene nuclear receptor coactivator 2 (NCOA2) has an established oncogenic role in early prostate cancer and likewise is a driver of metastatic disease and castration-resistant prostate cancer. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb05eac6614552e4b1dfc47ed114ed8
https://doi.org/10.1002/pros.24194
https://doi.org/10.1002/pros.24194
Autor:
Heidi Fettke, Louise Kostos, James Buteau, Jason A. Steen, Elizabeth Medhurst, Mo B. Haskali, Declan Murphy, Maria Docanto, Patricia Bukczynska, Nicole Ng, Shahneen Sandhu, Siavash Foroughi, Luc Furic, Tu Nguyen-Dumont, Michael S. Hofman, Arun A. Azad
Publikováno v:
Cancer Research. 83:5614-5614
[177Lu]Lu-PSMA-617 (LuPSMA) radionuclide therapy improves overall survival in mCRPC, and was recently approved by the FDA. Nevertheless, owing to the heterogeneous nature of mCRPC, responses to LuPSMA therapy can be variable, and resistance is inevit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::129d7c0027982a36e572f1f49231a3b4
https://doi.org/10.1158/1538-7445.am2023-5614
https://doi.org/10.1158/1538-7445.am2023-5614
Autor:
Derrick Theys, Melissa C. Southey, Maryam Mahmoodi, Fleur Hammet, Tu Nguyen-Dumont, Graham G. Giles, Daniel J. Park, Helen Tsimiklis, John L. Hopper, Bernard J. Pope, Mark Clendenning, Jason A. Steen, Ingrid Winship
Publikováno v:
Familial Cancer. 19:197-202
The advent of gene panel testing is challenging the previous practice of using clinically defined cancer family syndromes to inform single-gene genetic screening. Individual and family cancer histories that would have previously indicated testing of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70229d4e218ef83805f25cddaaf6b3c0
https://doi.org/10.1007/s10689-020-00164-7
https://doi.org/10.1007/s10689-020-00164-7
Autor:
Anne-Laure Renault, James G. Dowty, Jason A. Steen, Shuai Li, Ingrid M. Winship, Graham G. Giles, John L. Hopper, Melissa C. Southey, Tú Nguyen-Dumont
Publikováno v:
Breast cancer research : BCR. 24(1)
BackgroundMultigene panel tests for breast cancer predisposition routinely includeATMas it is now a well-established breast cancer predisposition gene.MethodsWe includedATMin a multigene panel test applied to the Australian Breast Cancer Family Regis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b14069726956c70c90d6cf3290320f5
https://pubmed.ncbi.nlm.nih.gov/35365198
https://pubmed.ncbi.nlm.nih.gov/35365198
Autor:
Melissa C. Southey, Fleur Hammet, Timothy McKay, Chenglong Yu, Maryam Mahmoodi, Jihoon E. Joo, Roger L. Milne, Jason A. Steen, John L. Hopper, Tu Nguyen-Dumont, Helen Tsimiklis, Derrick Theys, kConFab, Graham G. Giles, James G. Dowty, Ee Ming Wong, Pierre Antoine Dugué
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 5
International Journal of Molecular Sciences, Vol 22, Iss 2535, p 2535 (2021)
Volume 22
Issue 5
International Journal of Molecular Sciences, Vol 22, Iss 2535, p 2535 (2021)
VTRNA2-1 is a metastable epiallele with accumulating evidence that methylation at this region is heritable, modifiable and associated with disease including risk and progression of cancer. This study investigated the influence of genetic variation an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85ca22e861c2470a2b5ccd03c214daa4