Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Jason Greenbaum"'
Autor:
Mallory Paynich Murray, Isaac Engel, Grégory Seumois, Sara Herrera-De la Mata, Sandy Lucette Rosales, Ashu Sethi, Ashmitaa Logandha Ramamoorthy Premlal, Goo-Young Seo, Jason Greenbaum, Pandurangan Vijayanand, James P. Scott-Browne, Mitchell Kronenberg
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Invariant natural killer T cells are known to be composed of a number of phenotypic and functionally distinct populations. Here the authors use transcriptomic and epigenomic analysis to further characterize the peripheral iNKT compartment before and
Externí odkaz:
https://doaj.org/article/8fd3eb5a36ea4cf5a286dfc60609479d
Autor:
Chuan Wang, Kaïdre Bendjama, Stephen Schoenberger, Oliver Wood, Gareth Thomas, Pandurangan Vijayanand, Tilman Sanchez-Elsner, Nathalie Silvestre, Natalia Savelyeva, Christian Ottensmeier, Katy McCann, Adrian von Witzleben, Jaya Thomas, Divya Singh, Konstantinos Boukas, Finn Cilius Nielsen, Jason Greenbaum, Bjoern Peters
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 3 (2022)
Background Cancer is characterized by an accumulation of somatic mutations, of which a significant subset can generate cancer-specific neoepitopes that are recognized by autologous T cells. Such neoepitopes are emerging as important targets for cance
Externí odkaz:
https://doaj.org/article/f2e7b76ffbf04704a85332017c66893b
Autor:
Zeynep Koşaloğlu-Yalçın, Jenny Lee, Jason Greenbaum, Stephen P. Schoenberger, Aaron Miller, Young J. Kim, Alessandro Sette, Morten Nielsen, Bjoern Peters
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103850- (2022)
Summary: Many steps of the MHC class I antigen processing pathway can be predicted using computational methods. Here we show that epitope predictions can be further improved by considering abundance levels of peptides' source proteins. We utilized bi
Externí odkaz:
https://doaj.org/article/dee22334be9c400f97f173efaf88bffb
Autor:
Alba Grifoni, Hannah Voic, Esther Dawen Yu, Jose Mateus, Kai Mei Yan Fung, Alice Wang, Grégory Seumois, Aruna D. De Silva, Rashika Tennekon, Sunil Premawansa, Gayani Premawansa, Rashmi Tippalagama, Ananda Wijewickrama, Ashu Chawla, Jason Greenbaum, Bjoern Peters, Vijayanand Pandurangan, Daniela Weiskopf, Alessandro Sette
Publikováno v:
Vaccines, Vol 10, Iss 4, p 612 (2022)
While several lines of evidence suggest a protective role of T cells against disease associated with Dengue virus (DENV) infection, their potential contribution to immunopathology in the acute phase of DENV infection remains controversial, and it has
Externí odkaz:
https://doaj.org/article/97469ca26a384d278e732114634f117f
Autor:
Marcus Mendes, Jarjapu Mahita, Nina Blazeska, Jason Greenbaum, Brendan Ha, Kelly Wheeler, Jiyao Wang, Deborah Shackelford, Alessandro Sette, Bjoern Peters
Publikováno v:
Protein Science. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f81297a87d1bbd55f7a556110e13f2e9
https://doi.org/10.1002/pro.4605
https://doi.org/10.1002/pro.4605
Autor:
Zeynep Koşaloğlu-Yalçın, Manasa Lanka, Angela Frentzen, Ashmitaa Logandha Ramamoorthy Premlal, John Sidney, Kerrie Vaughan, Jason Greenbaum, Paul Robbins, Jared Gartner, Alessandro Sette, Bjoern Peters
Publikováno v:
OncoImmunology, Vol 7, Iss 11 (2018)
Epitopes that arise from a somatic mutation, also called neoepitopes, are now known to play a key role in cancer immunology and immunotherapy. Recent advances in high-throughput sequencing have made it possible to identify all mutations and thereby a
Externí odkaz:
https://doaj.org/article/f002e162cd5349459e9d923e4a132145
Autor:
Ilanit Gutman, Ron Gutman, John Sidney, Leila Chihab, Michele Mishto, Juliane Liepe, Anthony Chiem, Jason Greenbaum, Zhen Yan, Alessandro Sette, Zeynep Koşaloğlu-Yalçın, Bjoern Peters
Publikováno v:
Gutman, I, Gutman, R, Sidney, J, Chihab, L, Mishto, M, Liepe, J, Chiem, A, Greenbaum, J, Yan, Z, Sette, A, Koşaloǧlu-Yalçln, Z & Peters, B 2022, ' Predicting the Success of Fmoc-Based Peptide Synthesis ', ACS Omega, vol. 7, no. 27, pp. 23771-23781 . https://doi.org/10.1021/acsomega.2c02425
ACS Omega
ACS Omega
Synthetic peptides are commonly used in biomedical science for many applications in basic and translational research. While peptide synthesis is generally easy and reliable, the chemical nature of some amino acids as well as the many steps and chemic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c717df14a2c3519982dafc32ef9a0309
Autor:
Leila Yasmine Chihab, Zeynep Kosaloglu-Yalcin, Jason Greenbaum, Aaron Miller, Stephen Schoenberger, Bjoern Peters
Publikováno v:
Cancer Research. 82:2719-2719
Through somatic mutations, cancer cells accumulate cancer-specific mutated peptides, commonly referred to as neoepitopes or neoantigens, that can be recognized by T cells. Due to their cancer-specific nature, neoantigens are a highly attractive area
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6831f079352a1cb14757ee313eb2fe4
https://doi.org/10.1158/1538-7445.am2022-2719
https://doi.org/10.1158/1538-7445.am2022-2719
Autor:
Shilpi Chandra, Gabriel Ascui, Thomas Riffelmacher, Ashu Chawla, Ciro Ramirez-Suastegui, Viankail Cedillo Castelan, Gregory Seumois, Hayley Simon, Mallory Paynich Murray, Goo-Young Seo, Ashmitaa Logandha Ramamoorthy Premlal, Greet Verstichel, Yingcong Li, Chia-Hao Lin, Jason Greenbaum, John Lamberti, Raghav Murthy, John Nigro, Hilde Cheroutre, Christian H. Ottensmeier, Stephen M. Hedrick, Li-Fan Lu, Pandurangan Vijayanand, Mitchell Kronenberg
Mucosal-associated invariant T (MAIT) cells are a subpopulation of T lymphocytes that respond to microbial metabolites. We performed single-cell RNA sequencing and metabolic analyses of MAIT cell subsets in thymus and peripheral tissues from mice and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc0cfdc0713c6e65102b13d2dc0e0788
https://doi.org/10.1101/2021.12.20.473182
https://doi.org/10.1101/2021.12.20.473182
Autor:
Anna Gerasimova, Lukas Chavez, Bin Li, Gregory Seumois, Jason Greenbaum, Anjana Rao, Pandurangan Vijayanand, Bjoern Peters
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54359 (2013)
Genome-wide association studies (GWASs) identify single nucleotide polymorphisms (SNPs) that are enriched in individuals suffering from a given disease. Most disease-associated SNPs fall into non-coding regions, so that it is not straightforward to i
Externí odkaz:
https://doaj.org/article/2300a2de719f4f21b15b066e7832dbda