Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jason, Malphurs"'
Autor:
Pamela E. Blackshear, Kimberly A. McAllister, Barbara J. Davis, Donna O. Bunch, L. Michelle Bennett, Edward M. Eddy, Toni Ward, Jason Malphurs, N. Keith Collins, Gina Goulding, Roger W. Wiseman
Publikováno v:
Molecular Carcinogenesis. 28:174-183
Women who inherit mutations in the BRCA2 cancer susceptibility gene have an 85% chance of developing breast cancer. The function of the BRCA2 gene remains elusive, but there is evidence to support its role in transcriptional transactivation, tumor su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d86f5266990cfda583c51f54226cf7cc
https://doi.org/10.1002/1098-2744(200007)28:3<174::aid-mc6>3.0.co
https://doi.org/10.1002/1098-2744(200007)28:3<174::aid-mc6>3.0.co
Autor:
Bernd Nürnberg, Haruhiko Akiyama, Lutz Birnbaumer, Karsten Spicher, Jason Malphurs, Nicholas W. Plummer, Joel Abramowitz
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 109(52)
129/SvEv mice with a loss-of-function mutation in the heterotrimeric G protein α-subunit gene Gnai3 have fusions of ribs and lumbar vertebrae, indicating a requirement for Gα i (the “inhibitory” class of α-subunits) in somite derivatives. Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b883d2031e4227f878264bf48345e4ba
https://pubmed.ncbi.nlm.nih.gov/23236180
https://pubmed.ncbi.nlm.nih.gov/23236180
Autor:
Kimberly A. McAllister, Roger W. Wiseman, L. Michelle Bennett, Barbara J. Davis, Jason Malphurs, William Gersch, Laura Wharey, Toni Ward, Christopher D. Houle, Laura J. Betz, N. Keith Collins, John C. Seely
Publikováno v:
Toxicologic pathology. 34(2)
Mutations in both p53 and BRCA2 are commonly seen together in human tumors suggesting that the loss of both genes enhances tumor development. To elucidate this interaction in an animal model, mice lacking the carboxy terminal domain of Brca2 were cro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::629213d34c79a743bd6d12ca9b891df4
https://pubmed.ncbi.nlm.nih.gov/16546942
https://pubmed.ncbi.nlm.nih.gov/16546942
Autor:
Kimberly A, McAllister, L Michelle, Bennett, Chris D, Houle, Toni, Ward, Jason, Malphurs, N Keith, Collins, Carol, Cachafeiro, Joseph, Haseman, Eugenia H, Goulding, Donna, Bunch, E Mitch, Eddy, Barbara J, Davis, Roger W, Wiseman
Publikováno v:
Cancer research. 62(4)
Inherited mutations of the human BRCA2 gene confer increased risks for developing breast, ovarian, and several other cancers. Unlike previously described Brca2 knockout mice that display predominantly embryonic lethal phenotypes, we developed mice wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d46f7f8a5d40171ea4a8b3bd62abcce5
https://pubmed.ncbi.nlm.nih.gov/11861370
https://pubmed.ncbi.nlm.nih.gov/11861370
Autor:
Kimberly A. McAllister, N K Collins, K-U Wagner, Roger W. Wiseman, Edward M. Eddy, G Goulding, Jason Malphurs, Toni Ward, L M Bennett, Barbara J. Davis
Publikováno v:
Breast Cancer Research. 2
BRCA2 hereditary gene mutations confer a profound predisposition to breast cancer in women. We have generated mice carrying a Cre-loxP conditional Erca2 mutated allele by flanking exon 27 with loxP sites and we predict that this will disrupt basic fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5575445b30938c440418b281af3920a9
https://doi.org/10.1186/bcr150
https://doi.org/10.1186/bcr150
Autor:
Wesley Gladwell, Douglas A. Bell, Vijayalakshmi Panduri, Bennett Van Houten, Zachary R. McCaw, Jason Malphurs, Nicole Reeves, Tim Wiltshire, Jacqui Marzec, Greg Solomon, David C. Fargo, Kirsten C. Verhein, Jennifer L. Nichols, Steven R. Kleeberger, Adam B. Burkholder
Publikováno v:
ResearcherID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43e573113aa1cdb9d72c2de830662c5e
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000209838203188&KeyUID=WOS:000209838203188
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000209838203188&KeyUID=WOS:000209838203188
