Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Jason, Dang"'
Publikováno v:
Emerging Microbes and Infections, Vol 6, Iss 1, Pp 1-10 (2017)
Zika virus (ZIKV) is an emerging virus causally linked to neurological disorders, including congenital microcephaly and Guillain–Barré syndrome. There are currently no targeted therapies for ZIKV infection. To identify novel antiviral targets and
Externí odkaz:
https://doaj.org/article/97012bda7b00487ba976de023e6e53ab
Autor:
Benjamin W. Jester, Hui Zhao, Mesfin Gewe, Thomas Adame, Lisa Perruzza, David T. Bolick, Jan Agosti, Nhi Khuong, Rolf Kuestner, Caitlin Gamble, Kendra Cruickshank, Jeremy Ferrara, Rachelle Lim, Troy Paddock, Colin Brady, Stacey Ertel, Miaohua Zhang, Alex Pollock, Jamie Lee, Jian Xiong, Michael Tasch, Tracy Saveria, David Doughty, Jacob Marshall, Damian Carrieri, Lauren Goetsch, Jason Dang, Nathaniel Sanjaya, David Fletcher, Anissa Martinez, Bryce Kadis, Kristjan Sigmar, Esha Afreen, Tammy Nguyen, Amanda Randolph, Alexandria Taber, Ashley Krzeszowski, Brittney Robinett, David B. Volkin, Fabio Grassi, Richard Guerrant, Ryo Takeuchi, Brian Finrow, Craig Behnke, James Roberts
Publikováno v:
Nature Biotechnology. 40:956-964
The use of the edible photosynthetic cyanobacterium Arthrospira platensis (spirulina) as a biomanufacturing platform has been limited by a lack of genetic tools. Here we report genetic engineering methods for stable, high-level expression of bioactiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc72201487f5ff22957927d75b57374
https://doi.org/10.1038/s41587-022-01249-7
https://doi.org/10.1038/s41587-022-01249-7
Autor:
Tariq M. Rana, Jorge Moscat, Pedro Aza-Blanc, Edwin Yau, Kung-Yen Chang, Jason Dang, Ying Zhou
Legend for Supplementary Figures S1-S8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69debb5d1a07c647750264d4df7f610c
https://doi.org/10.1158/0008-5472.22409370
https://doi.org/10.1158/0008-5472.22409370
Autor:
Tariq M. Rana, Jorge Moscat, Pedro Aza-Blanc, Edwin Yau, Kung-Yen Chang, Jason Dang, Ying Zhou
Mutation Background of Non-Small Cell Lung Cancer Lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27282fb5154809d29e82455f7a2b097f
https://doi.org/10.1158/0008-5472.22409364.v1
https://doi.org/10.1158/0008-5472.22409364.v1
Autor:
Tariq M. Rana, Jorge Moscat, Pedro Aza-Blanc, Edwin Yau, Kung-Yen Chang, Jason Dang, Ying Zhou
Global miRNA functional screens can offer a strategy to identify synthetic lethal interactions in cancer cells that might be exploited therapeutically. In this study, we applied this strategy to identify novel gene interactions in KRAS-mutant cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::009ff748eaa51cc0f03f183fc92ff771
https://doi.org/10.1158/0008-5472.c.6507762
https://doi.org/10.1158/0008-5472.c.6507762
Autor:
Hui Zhao, Michael Dodds, Michael Tasch, Mesfin Gewe, Anissa Martinez, Melanie Hutton, Kristie Keeney, Alex Pollock, Benjamin W. Jester, Nhi Khuong, Mia Zhang, Stacey Ertel, Colin Brady, Mark Heinnickel, Hannah Tabakh, Nathan Sanjaya, Kendra Cruickshank, Troy Paddock, Sarah Struyvenberg, Jason Dang, Tracy Saveria, Chelsea Shanitta, David Fletcher, Kristjan Sigmar, Lauren Goetsch, Caitlin Gamble, Steven J. Mileto, Ryan Heselpoth, Dena Lyras, Craig A. Behnke, Vincent Fischetti, Brian Finrow, James M. Roberts
Drugs which independently inhibit a shared target or pathway can have synthetic activities that result in multiplicative instead of merely additive potencies. This characteristic of drug combinations can be quantified by expressing the potency of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3acc58ac9dbf12a359540fab7049897
https://doi.org/10.1101/2021.12.21.473715
https://doi.org/10.1101/2021.12.21.473715
Autor:
James A. Roberts, Marc Berndl, Drew Bryant, Damian Carrieri, Jacob Marshall, Eli Bixby, Jason Dang, Lucy J. Colwell, David M. Doughty, Michael Frumkin, Caitlin Gamble
BackgroundArthrospira platensis (commonly known as spirulina) is a promising new platform for low-cost manufacturing of biopharmaceuticals. However, full realization of the platform’s potential will depend on achieving both high growth rates of spi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f36488a2dd62465fd84e766faee731c
https://doi.org/10.1101/2021.08.06.453272
https://doi.org/10.1101/2021.08.06.453272
Autor:
Jason Dang, Timothy D. Arthur, Zhenjiang Zech Xu, Rodolfo A. Salido, Cameron Martino, Rob Knight, James Gaffney, Jon G. Sanders, Mahdieh Khosroheidari, Greg Humphrey, Jeremiah J. Minich, Brigid S. Boland, Kristen Jepsen, Qiyun Zhu, John T. Chang, Marlon Liyanage, Pieter C. Dorrestein, Robert A. Quinn, Douglas Conrad, Karenina Sanders, Caitriona Brennan, Feng Chen, William J. Sandborn, Marcus W. Fedarko, Cliff Green, Larry Smarr, Pavel A. Pevzner, Anton Bankevich, Tariq M. Rana, Sergey Nurk, Vanessa V. Phelan
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-14 (2019)
Genome biology, vol 20, iss 1
Genome Biology
Genome biology, vol 20, iss 1
Genome Biology
As metagenomic studies move to increasing numbers of samples, communities like the human gut may benefit more from the assembly of abundant microbes in many samples, rather than the exhaustive assembly of fewer samples. We term this approach leaderbo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deb3b955c172d0cbd4d56dcb79affbfe
http://link.springer.com/article/10.1186/s13059-019-1834-9
http://link.springer.com/article/10.1186/s13059-019-1834-9
Publikováno v:
Cell Reports, Vol 27, Iss 12, Pp 3618-3628.e5 (2019)
Cell reports
Cell reports, vol 27, iss 12
Cell reports
Cell reports, vol 27, iss 12
SUMMARY Zika virus (ZIKV) infection is implicated in severe fetal developmental disorders, including microcephaly. MicroRNAs (miRNAs) post-transcriptionally regulate numerous processes associated with viral infection and neurodegeneration, but their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74dd4ee1d000325c0a1c913cadcb09e6
http://www.sciencedirect.com/science/article/pii/S2211124719306886
http://www.sciencedirect.com/science/article/pii/S2211124719306886
Publikováno v:
Molecular psychiatry, vol 26, iss 4
Molecular psychiatry
Molecular psychiatry
Methamphetamine (METH) is a potent stimulant that induces a euphoric state but also causes cognitive impairment, neurotoxicity and neurodevelopmental deficits. Yet, the molecular mechanisms by which METH causes neurodevelopmental defects have remaine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc79bb90813777692c7c7f23747344b7
https://escholarship.org/uc/item/4m65w1jg
https://escholarship.org/uc/item/4m65w1jg