Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jasna Levi"'
Autor:
Steven J.M. Jones, Stephen Yip, Christof Senger, William T. Gibson, Patrice Eydoux, Ana S A Cohen, Margaret L. McKinnon, Qing-San Xiang, Scott A. Lear, Jasna Levi, Raj Attariwala, Christof Borchers, Wayne Picker, Katelin N. Townsend, Siu-Li Yong, Amy Lum, Robert Everett, Lila Yewchuk, Joelle Tan
Publikováno v:
American Journal of Medical Genetics Part A. 164:2360-2364
We describe a patient who presented with a localized growth of mature fat tissue, which was surgically removed. MRI imaging identified diffuse increase in visceral adipose tissue. Targeted deep sequencing of the resected tissue uncovered a p.H1047R v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::762e2e9852a131ce30737942e5474667
https://doi.org/10.1002/ajmg.a.36622
https://doi.org/10.1002/ajmg.a.36622
Autor:
Madeleine Speck, William T. Gibson, Jasna Levi, Sarah L. Gray, Sandra L. Babich, Frank K. Huynh, Timothy J. Kieffer
Publikováno v:
Endocrinology. 152:3385-3395
Leptin, an adipocyte-derived hormone, plays an essential role in the maintenance of normal body weight and energy expenditure, as well as glucose homeostasis. Indeed, leptin-deficient ob/ob mice are obese with profound hyperinsulinemia, insulin resis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af0c568df9a0810599b80e967600aee9
https://doi.org/10.1210/en.2011-0185
https://doi.org/10.1210/en.2011-0185
Autor:
Timothy J. Kieffer, Frank K. Huynh, Rhonda D. Wideman, Roveena M. Sequeira, Scott D. Covey, Jasna Levi, Heather C. Denroche
Publikováno v:
Diabetes
OBJECTIVE Leptin therapy has been found to reverse hyperglycemia and prevent mortality in several rodent models of type 1 diabetes. Yet the mechanism of leptin-mediated reversal of hyperglycemia has not been fully defined. The liver is a key organ re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::900a0d1e1e60f3b4afe570a5565c04f3
https://doi.org/10.2337/db10-0958
https://doi.org/10.2337/db10-0958
Autor:
Scott D. Covey, Jasna Levi, Sarah L. Gray, Heather C. Denroche, Madeleine Speck, Timothy J. Kieffer, Ursula H. Neumann, Frank K. Huynh, Peter J. Voshol, Streamson C. Chua
Publikováno v:
Diabetes
OBJECTIVE The liver plays a critical role in integrating and controlling glucose metabolism. Thus, it is important that the liver receive and react to signals from other tissues regarding the nutrient status of the body. Leptin, which is produced and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d35209069967716ad2bc2cede83b4b
https://doi.org/10.2337/db10-0074
https://doi.org/10.2337/db10-0074
Autor:
Jasna Levi, Joseph M. Lam
Publikováno v:
Paediatrics & Child Health. 21:135-136
A 12-year-old girl was referred for a two-month history of hyperpigmented lesions on her anterior neck. Her medical history was significant for treatment with clobazam for unprovoked seizure two months before appearance of lesions. She was otherwise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81de8a14dabf9f9f97a9a4ffcf80dde8
https://doi.org/10.1093/pch/21.3.135a
https://doi.org/10.1093/pch/21.3.135a
Publikováno v:
Canadian Journal of Surgery. 58:69-70
With modern anesthesia, aspiration is an exceedingly rare complication, and we have learned that a prolonged fast can result in serious adverse effects in critically ill patients. We discuss the no-fast protocol implemented at Vancouver General Hospi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa446d4e982fa0652623d44423ada46b
https://doi.org/10.1503/cjs.027213
https://doi.org/10.1503/cjs.027213
Autor:
Timothy J. Kieffer, Ursula H. Neumann, Heather C. Denroche, Scott D. Covey, Jasna Levi, Maria M. Glavas, Frank K. Huynh
Publikováno v:
Diabetologia. 55(3)
The fat-derived hormone leptin plays a crucial role in the maintenance of normal body weight and energy expenditure as well as in glucose homeostasis. Recently, it was reported that the liver-derived protein, insulin-like growth factor binding protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a9d653b99865cce898cdbc75bb464a3
https://pubmed.ncbi.nlm.nih.gov/22202803
https://pubmed.ncbi.nlm.nih.gov/22202803
Autor:
Iran Tavakoli, Anna Fronda, Kevin McClintock, Lina Hu, Adam Judge, Jasna Levi, Ellen Grace Ambegia, Marjorie Robbins, Ian MacLachlan
siRNAs that specifically silence the expression of cancer-related genes offer a therapeutic approach in oncology. However, it remains critical to determine the true mechanism of their therapeutic effects. Here, we describe the preclinical development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0df57fbf49b67e345986b042c959d50
https://europepmc.org/articles/PMC2648695/
https://europepmc.org/articles/PMC2648695/
Publikováno v:
Canadian Journal of Diabetes. 39:531
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aefb9945d77ea807c0db539e88ca3aef
https://doi.org/10.1016/j.jcjd.2015.09.024
https://doi.org/10.1016/j.jcjd.2015.09.024
Autor:
Timothy J. Kieffer, Scott D. Covey, Jasna Levi, Madeleine Speck, Sarah L. Gray, Frank K. Huynh, Streamson C. Chua, Peter J. Voshol
Publikováno v:
Canadian Journal of Diabetes. 32:305
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::575cefef3a4a420f2ee30f8b63988091
https://doi.org/10.1016/s1499-2671(08)24028-1
https://doi.org/10.1016/s1499-2671(08)24028-1