Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jasmit Kaur"'
Publikováno v:
Ecotoxicology. 23:967-977
Harike is a wetland of international importance under the Ramsar Convention. The present study entails the investigation of mutagenic, genotoxic and cytotoxic effect of surface water samples collected from five different areas of the Harike wetland b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c36d6441541f737e930adf2f509329d1
https://doi.org/10.1007/s10646-014-1240-8
https://doi.org/10.1007/s10646-014-1240-8
Autor:
Laurent Salphati, Stewart J. Baker, Steve Price, Jim Nonomiya, Matthew C. Lucas, Timothy Hancox, David Knowles, Bohdan Waszkowycz, Neil Anthony Pegg, David Chantry, Bryan K. Chan, Paul Blaney, Anthony Brown, Steven T. Staben, Jodie Pang, Paul Depledge, Rama K. Kondru, Mark Ultsch, Paul Goldsmith, Karin Reif, Angelina Bisconte, Cristina Lewis, Eileen Mary Seward, Jeremy Murray, Brian Safina, Daniel P. Sutherlin, Zachary Kevin Sweeney, Georgette Castanedo, David Michael Goldstein, Jasmit Kaur, Sukhjit Sohal, Binqing Wei, John Lesnick, Stephen J. Shuttleworth, Alan Nadin
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:4296-4302
A potent inhibitor of PI3Kδ that is ⩾200 fold selective for the remaining three Class I PI3K isoforms and additional kinases is described. The hypothesis for selectivity is illustrated through structure activity relationships and crystal structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92be9aea35b7ac14f79d9d789ee6948b
https://doi.org/10.1016/j.bmcl.2012.05.027
https://doi.org/10.1016/j.bmcl.2012.05.027
Autor:
Steve Price, Georgette Castanedo, Fernando Padilla, Bohdan Waszkowycz, Christine Chabot, Neil Anthony Pegg, Laurent Salphati, Alan Nadin, Jun Li, Karin Reif, Raj K. Handa, Arnaud J. Cheguillaume, Timothy Hancox, Suzanne Tay, Pascal Savy, Parcharee Tivitmahaisoon, Zachary Kevin Sweeney, Jeremy Murray, Binqing Wei, Krintel Sussie Lerche, Qin Yue, Eileen Mary Seward, Sophie Mukadam, Rama K. Kondru, Pravin Iyer, Sukhjit Sohal, Jasmit Kaur, John Lesnick, Yung-Hsiang Chen, Daniel P. Sutherlin, Stephen J. Shuttleworth, Matthew W. Cartwright, Bindu Goyal, Paul M. Blaney, Paul Goldsmith, Jodie Pang, Matthew C. Lucas, Stewart J. Baker, Jim Nonomiya, Cristina Lewis, Wylie Solang Palmer, Chenghong Zhang, Brian Safina, Matt Baumgardner, Bryan K. Chan, David Michael Goldstein, Jane R. Kenny
Publikováno v:
Journal of medicinal chemistry. 55(12)
PI3Kδ is a lipid kinase and a member of a larger family of enzymes, PI3K class IA(α, β, δ) and IB (γ), which catalyze the phosphorylation of PIP2 to PIP3. PI3Kδ is mainly expressed in leukocytes, where it plays a critical, nonredundant role in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f3151193dd85c9e07e1ac655378624
https://pubmed.ncbi.nlm.nih.gov/22626259
https://pubmed.ncbi.nlm.nih.gov/22626259
Autor:
Ajay K. Sharma, Velu Nair, Jyoti Kotwal, Sanjeevan Sharma, Jasmit Kaur, Sataya Ranjan Das, Rajeev Kumar, Jasjit Singh
Publikováno v:
Blood. 124:5947-5947
Background: Despite intensive remission induction chemotherapy, up to 5–10% AYAs with acute lymphoblastic leukemia (ALL) are primarily refractory.1,2 Of those that achieve a remission, as much as 70–80% fail consolidation largely due to relapse o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d16c79b061a655421f5920b4b3dac1a7
https://doi.org/10.1182/blood.v124.21.5947.5947
https://doi.org/10.1182/blood.v124.21.5947.5947
Publikováno v:
Journal of computer-aided molecular design. 18(10)
An approach for docking covalently bound ligands in protein enzymes or receptors was implemented in MacDOCK, a similarity-driven docking program based on DOCK 4.0. This approach was tested with a small number of covalent ligand-protein structures, us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f448af4dac446037c11f3c7dc82c2710
https://pubmed.ncbi.nlm.nih.gov/15849994
https://pubmed.ncbi.nlm.nih.gov/15849994
Publikováno v:
Organicbiomolecular chemistry. 1(23)
A collection of small molecules (MW350 Da) was screened for binding to human factor Xa using saturation transfer difference NMR spectroscopy to detect binding. The NMR screening experiments identified four hits. Binding isotherms constructed from NMR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a83adc9e6533591f70401740ad8561b
https://pubmed.ncbi.nlm.nih.gov/14685325
https://pubmed.ncbi.nlm.nih.gov/14685325
Autor:
Zhang Mingqiang, Alan W. Muir, Grove Simon James Anthony, Eleanor Pow, Jasmit Kaur, Gary J. Tarver
Publikováno v:
Bioorganicmedicinal chemistry letters. 12(2)
A series of oxyanilinium-based AChE inhibitors have been synthesised and tested for the reversal of vecuronium-induced neuromuscular block. Several compounds, for example 2-hydroxy- and 2-methoxy-N,N-dimethyl-N-allylanilinium bromide (3 and 6) showed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcba3ec20df3b034c70ac69028c9a64c
https://pubmed.ncbi.nlm.nih.gov/11755352
https://pubmed.ncbi.nlm.nih.gov/11755352
Publikováno v:
Spatula DD - Peer Reviewed Journal on Complementary Medicine and Drug Discovery. 2:165
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b37f761820861f8b6f3e9021c3bcbc0
https://doi.org/10.5455/spatula.20120917112347
https://doi.org/10.5455/spatula.20120917112347
Publikováno v:
Applied Water Science. 7(3):1107-1115
The present study entails the investigation of mutagenic and genotoxic effect of surface water samples collected from 13 different sites of the Harike wetland using the histidine reversion point mutation assay in Salmonella typhimurium (TA98) strain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e70eec90b2264753127154303d60ef32
Autor:
Puri, Maria mariaskakujpuri@gmail.com
Publikováno v:
Cracow Indological Studies. 2021, Vol. 23 Issue 1, p91-136. 46p.