Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Jasmini Alagaratnam"'
Autor:
Jasmini Alagaratnam, Wolfgang Stöhr, Elizabeth Hamlyn, Kholoud Porter, Jamie Toombs, Amanda Heslegrave, Henrik Zetterberg, Magnus Gisslén, Jonathan Underwood, Mauro Schechter, Pontiano Kaleebu, Giuseppe Tambussi, Sabine Kinloch, Jose M. Miro, Anthony D. Kelleher, Abdel Babiker, John Frater, Alan Winston, Sarah Fidler
Publikováno v:
Journal of Virus Eradication, Vol 10, Iss 2, Pp 100381- (2024)
Objective: Antiretroviral therapy (ART)-conferred suppression of HIV replication limits neuronal injury and inflammation. ART interruption tests efficacy in HIV cure trials and viral rebound after ART interruption may induce neuronal injury. We inves
Externí odkaz:
https://doaj.org/article/487cf33da3b34fe190f0b5145c56c047
Autor:
Arish Mudra Rakshasa-Loots, Nicholas Bakewell, David J. Sharp, Magnus Gisslén, Henrik Zetterberg, Jasmini Alagaratnam, Ferdinand W. N. M. Wit, Neeltje A. Kootstra, Alan Winston, Peter Reiss, Caroline A. Sabin, Jaime H. Vera, on behalf of the COmorBidity in Relation to AIDS (COBRA) cohort
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract People living with HIV are at increased risk for depression, though the underlying mechanisms for this are unclear. In the general population, depression is associated with peripheral and central inflammation. Given this, and since HIV infec
Externí odkaz:
https://doaj.org/article/a7e102dc1cdb4eb5bc3d97d6a62608b8
Autor:
Alex J. Szubert, Katrina M. Pollock, Hannah M. Cheeseman, Jasmini Alagaratnam, Henry Bern, Olivia Bird, Marta Boffito, Ruth Byrne, Tom Cole, Catherine A. Cosgrove, Saul N. Faust, Sarah Fidler, Eva Galiza, Hana Hassanin, Mohini Kalyan, Vincenzo Libri, Leon R. McFarlane, Ana Milinkovic, Jessica O'Hara, David R. Owen, Daniel Owens, Mihaela Pacurar, Tommy Rampling, Simon Skene, Alan Winston, James Woolley, Yee Ting N. Yim, David T. Dunn, Sheena McCormack, Robin J. Shattock
Publikováno v:
EClinicalMedicine, Vol 56, Iss , Pp 101823- (2023)
Summary: Background: Lipid nanoparticle (LNP) encapsulated self-amplifying RNA (saRNA) is well tolerated and immunogenic in SARS-CoV-2 seronegative and seropositive individuals aged 18–75. Methods: A phase 2a expanded safety and immunogenicity stud
Externí odkaz:
https://doaj.org/article/8c3e3b38ed0a4f79b89d74a152895c3b
Autor:
Ane Ogbe, Matthew Pace, Mustapha Bittaye, Timothy Tipoe, Sandra Adele, Jasmini Alagaratnam, Parvinder K. Aley, M. Azim Ansari, Anna Bara, Samantha Broadhead, Anthony Brown, Helen Brown, Federica Cappuccini, Paola Cinardo, Wanwisa Dejnirattisai, Katie J. Ewer, Henry Fok, Pedro M. Folegatti, Jamie Fowler, Leila Godfrey, Anna L. Goodman, Bethany Jackson, Daniel Jenkin, Mathew Jones, Stephanie Longet, Rebecca A. Makinson, Natalie G. Marchevsky, Moncy Mathew, Andrea Mazzella, Yama F. Mujadidi, Lucia Parolini, Claire Petersen, Emma Plested, Katrina M. Pollock, Thurkka Rajeswaran, Maheshi N. Ramasamy, Sarah Rhead, Hannah Robinson, Nicola Robinson, Helen Sanders, Sonia Serrano, Tom Tipton, Anele Waters, Panagiota Zacharopoulou, Eleanor Barnes, Susanna Dunachie, Philip Goulder, Paul Klenerman, Gavin R. Screaton, Alan Winston, Adrian V.S. Hill, Sarah C. Gilbert, Miles Carroll, Andrew J. Pollard, Sarah Fidler, Julie Fox, Teresa Lambe, John Frater
Publikováno v:
JCI Insight, Vol 7, Iss 7 (2022)
Duration of protection from SARS-CoV-2 infection in people living with HIV (PWH) following vaccination is unclear. In a substudy of the phase II/III the COV002 trial (NCT04400838), 54 HIV+ male participants on antiretroviral therapy (undetectable vir
Externí odkaz:
https://doaj.org/article/446dfee8ec4944f5951afc9fd4bc0066
Autor:
Jasmini Alagaratnam, Helen Peters, Kate Francis, Natasha Kay, Yvonne Gilleece, Fionnuala P. Finnerty, Rosanna E. Grimes, Sarah Parry, Mags Portman, Brenton C. Wait, Rimi Shah, Sherie Roedling, David A. Hawkins, Sarah Chitty, Liat Sarner, Rebecca Marcus, Anna Hartley, Achyuta V. Nori, Melanie Rosenvinge, Graham P. Taylor, the London HIV Perinatal Research Group
Publikováno v:
AIDS Research and Therapy, Vol 17, Iss 1, Pp 1-9 (2020)
Abstract Background In pregnancy, reduction of HIV plasma viral load (pVL) for the prevention of vertical transmission is time-constrained. The study primary objective is to investigate factors associated with faster initial HIV RNA half-life decay w
Externí odkaz:
https://doaj.org/article/a8a9f2d6c63c4ea29ce8df1606da5dbf
Autor:
Jasmini Alagaratnam, Wolfgang Stöhr, Jamie Toombs, Amanda Heslegrave, Henrik Zetterberg, Magnus Gisslén, Sarah Pett, Mark Nelson, Amanda Clarke, Nneka Nwokolo, Margaret A. Johnson, Maryam Khan, Tomas Hanke, Jakub Kopycinski, Lucy Dorrell, Julie Fox, Sabine Kinloch, Jonathan Underwood, Matthew Pace, John Frater, Alan Winston, Sarah Fidler
Publikováno v:
Journal of Virus Eradication, Vol 7, Iss 3, Pp 100056- (2021)
Objective: HIV-remission strategies including kick-and-kill could induce viral transcription and immune-activation in the central nervous system, potentially causing neuronal injury. We investigated the impact of kick-and-kill on plasma neurofilament
Externí odkaz:
https://doaj.org/article/e67c8ca158464981987f7ea91b16fef1
Autor:
Henrik Zetterberg, Sarah Fidler, Alan Winston, Jonathan Underwood, Davide De Francesco, Paul Edison, Jasmini Alagaratnam, Sophia von Widekind
Publikováno v:
BMJ Neurology Open, Vol 3, Iss 1 (2021)
Objective To assess the overall pooled correlation coefficient estimate between cerebrospinal fluid (CSF) and blood neurofilament light (NfL) protein.Methods We searched Medline, Embase and Web of Science for published articles, from their inception
Externí odkaz:
https://doaj.org/article/c25be0973a0840dc9f50769cdcd337b5
Autor:
Christina K. Psomas, Laura Waters, Tristan Barber, Sarah Fidler, Malcolm Macartney, Jasmini Alagaratnam, Buddhika Perera, Sabine Kinloch
Publikováno v:
Journal of Virus Eradication, Vol 5, Iss 4, Pp 245-252 (2019)
Externí odkaz:
https://doaj.org/article/629196f8455442b89a66598db89e89e4
Autor:
Sarah Fidler, Jintanat Ananworanich, Linos Vandekerckhove, Maja Kiselinova, Alexandra Schuetz, Jaime H. Vera, Ellen Dwyer, Jasmini Alagaratnam
Publikováno v:
Journal of Virus Eradication, Vol 2, Iss 2, Pp 124-130 (2016)
Externí odkaz:
https://doaj.org/article/5a229e5a1ab441a188deed51ee154f25
Autor:
Jaime H. Vera, Margherita Bracchi, Jasmini Alagaratnam, Julianne Lwanga, Julie Fox, Alan Winston, Marta Boffito, Mark Nelson
Publikováno v:
Brain Sciences, Vol 9, Iss 8, p 195 (2019)
Objective: Occult central nervous system (CNS) symptoms not recognized by people living with HIV (PLWH) receiving efavirenz or their clinicians could occur and impact people’s quality of life. The aim of this study was to determine whether CNS para
Externí odkaz:
https://doaj.org/article/9d5b81625ce84cb7acdf905b4877d7cf