Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jasmine N. Tutol"'
Autor:
Jasmine N. Tutol, Whitney S. Y. Ong, Shelby M. Phelps, Weicheng Peng, Helen Goenawan, Sheel C. Dodani
Publikováno v:
ACS Central Science, Vol 10, Iss 1, Pp 77-86 (2023)
Externí odkaz:
https://doaj.org/article/11cf6f5d5378426ab8f28404ee5d45e9
Autor:
Jasmine N. Tutol, Whitney S. Y. Ong, Liangdong Zhu, Cheng Chen, Chong Fang, Sheel C. Dodani, Longteng Tang
Publikováno v:
Chemical Science
Natural and laboratory-guided evolution has created a rich diversity of fluorescent protein (FP)-based sensors for chloride (Cl−). To date, such sensors have been limited to the Aequorea victoria green fluorescent protein (avGFP) family, and fusion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e95cf3d1a191a37f7a058c72dc0ae890
http://europepmc.org/articles/PMC8447875
http://europepmc.org/articles/PMC8447875
Autor:
Jasmine N. Tutol, Whitney S. Y. Ong, Shelby M. Phelps, Weicheng Peng, Helen Goenawan, Sheel C. Dodani
Chloride is a ubiquitous ion essential for regulating biological processes. Long thought to be just a counterion in biological systems, chloride is emerging as a vital anion that plays a major role in a range of diseases. The ability to visualize int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9637fdfb2ea1a3e15b0a1887b86ae5d8
https://doi.org/10.1101/2022.08.13.503807
https://doi.org/10.1101/2022.08.13.503807
Autor:
Farah N. Faizuddin, Sheel C. Dodani, Jasmine N. Tutol, Jessica Lee, Faruck Morcos, Qin Zhou, Gabriele Meloni, Hsichuan Chi, Sameera S. Abeyrathna
Publikováno v:
Chemical Science
The visualization of chloride in living cells with fluorescent sensors is linked to our ability to design hosts that can overcome the energetic penalty of desolvation to bind chloride in water. Fluorescent proteins can be used as biological supramole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdc47b9b3927d3fa7f16a7be009a07cd
http://europepmc.org/articles/PMC8179538
http://europepmc.org/articles/PMC8179538
Autor:
Hsichuan Chi, Qin Zhou, Jasmine N. Tutol, Shelby M. Phelps, Jessica Lee, Paarth Kapadia, Faruck Morcos, Sheel C. Dodani
Publikováno v:
ACS Synth Biol
Our understanding of chloride in biology can be accelerated through the application of fluorescent protein-based sensors in living cells. Laboratory-guided evolution can be used to diversify and identify sensors with specific properties. Recently, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70266ee7663784c5e8dd14552dea6c8b
https://europepmc.org/articles/PMC9184236/
https://europepmc.org/articles/PMC9184236/
Autor:
Jasmine N. Tutol, Sheena D'Arcy, Kierstin M Page, Regina A. Baglia, Steven O. Nielsen, Sheel C. Dodani, Jyothi Kallu, Koushambi Mitra, Sriharika Gottipolu, Kira R Mills, Darby Ball
Publikováno v:
Rsc Chemical Biology
Human phenol sulfotransferases mediate the transfer of a sulfuryl moiety from the activated sulfate donor PAPS to hydroxy-containing substrates, altering substrate solubility and charge to affect phase II metabolism and cell signaling. Here, we prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cd675c07fbaadcd5e7a29045027f3e2
https://doi.org/10.26434/chemrxiv.13215167.v1
https://doi.org/10.26434/chemrxiv.13215167.v1
Autor:
Jasmine N. Tutol, Tahir S. Qasim, Gabriele Meloni, Sheel C. Dodani, Ved Prakash, Marc J. Gallenito
Publikováno v:
Metallomics
Platinum-coordination complexes are among the most effective chemotherapeutic drugs used in clinics for the treatment of cancer. Despite their efficacy, cancer cells can develop drug resistance leading to treatment failure and relapse. Cellular uptak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d575a00a703c133528ad077629c9de35
https://europepmc.org/articles/PMC7578072/
https://europepmc.org/articles/PMC7578072/
Autor:
Sameera S. Abeyrathna, Hsichuan Chi, Jasmine N. Tutol, Jessica C. Lee, Gabriele Meloni, Faruck Morcos, Qin Zhou, Sheel C. Dodani, Farah N. Faizuddin
The visualization of chloride in living cells with fluorescent sensors is linked to our ability to design hosts that can overcome the energetic penalty of desolvation to bind chloride in water. Fluorescent proteins can be used as biological supramole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62aaa9faa06e854ce96ec0a57567910f
https://doi.org/10.26434/chemrxiv.13028192.v1
https://doi.org/10.26434/chemrxiv.13028192.v1
Publikováno v:
Biochemistry. 58:31-35
Fluorescent proteins have been extensively engineered and applied as optical indicators for chloride in a variety of biological contexts. Surprisingly, given the biodiversity of fluorescent proteins, a naturally occurring chloride sensor has not been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f43400eb0d3ebcbc6ba199c13625c3f
https://doi.org/10.1021/acs.biochem.8b00928
https://doi.org/10.1021/acs.biochem.8b00928
Publikováno v:
Chembiochem
Chloride-sensitive fluorescent proteins generated from laboratory evolution have a characteristic tyrosine residue that interacts with a chloride ion and π-stacks with the chromophore. However, the engineered yellow-green fluorescent protein mNeonGr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d165a35a2fdfacf8fd3fa54282c1269
https://doi.org/10.1002/cbic.201900408
https://doi.org/10.1002/cbic.201900408