Clonal evolution and stereotyped sequences of human IgE lineages in aeroallergen-specific immunotherapy

Autor: Ramona A. Hoh, Linnea Thörnqvist, Fan Yang, Magdalena Godzwon, Jasmine J. King, Ji-Yeun Lee, Lennart Greiff, Scott D. Boyd, Mats Ohlin

Publikováno v: Journal of Allergy and Clinical Immunology.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7978bcf58f4a40bb6cda59a9abce5453
https://doi.org/10.1016/j.jaci.2023.02.009

Single B-cell deconvolution of peanut-specific antibody responses in allergic patients

Autor: Kari C. Nadeau, Tim J. Looney, Tho D. Pham, Jasmine J. King, Ramona A. Hoh, Jennifer A. Jenks, Katherine J. L. Jackson, Krishna M. Roskin, Robert G. Hamilton, Chen Wang, Ji Yeun Lee, Yi Liu, Scott D. Boyd, Shilpa A. Joshi, Shu Chen Lyu, Vaishali P. Dixit

Publikováno v: Journal of Allergy and Clinical Immunology. 137:157-167

Background The frequencies, cellular phenotypes, epitope specificity, and clonal diversity of allergen-specific B cells in patients with food allergy are not fully understood but are of major pathogenic and therapeutic significance. Objective We soug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::097356843a0b95f92f4a3e7913c5bbc8
https://doi.org/10.1016/j.jaci.2015.05.029

Comprehensive whole-genome sequencing of an early-stage primary myelofibrosis patient defines low mutational burden and non-recurrent candidate genes

Autor: Rhonda Hewitt, Dana Ng, Carol D. Jones, Michael Snyder, Jason D. Merker, Krishna M. Roskin, James L. Zehnder, Jasmine J. King, Scott D. Boyd, Linda Gojenola, Lawrence M. Okumoto, Athena M. Cherry, Parveen Abidi, Michael Stadler, Tracy I. George, Dianna G. Fisk, Andrew Fire, Bing Zhang, Cuiping Pan, Ramona A. Hoh, Jason Gotlib, Michael J. Clark

Publikováno v: Haematologica. 98(11)

In order to identify novel somatic mutations associated with classic BCR/ABL1-negative myeloproliferative neoplasms, we performed high-coverage genome sequencing of DNA from peripheral blood granulocytes and cultured skin fibroblasts from a patient w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::449b2183cd4e08bd32a8d14b0ff57b4e
https://pubmed.ncbi.nlm.nih.gov/23872309

Differential impact of sex on regulation of skeletal muscle mitochondrial function and protein homeostasis by hypoxia-inducible factor-1α in normoxia.

Autor: Welch N; Departments of Inflammation and Immunity, Gastroenterology & Hepatology, Cleveland Clinic, Cleveland, OH, USA., Mishra S; Departments of Inflammation and Immunity, Gastroenterology & Hepatology, Cleveland Clinic, Cleveland, OH, USA., Bellar A; Departments of Inflammation and Immunity, Gastroenterology & Hepatology, Cleveland Clinic, Cleveland, OH, USA., Kannan P; Departments of Inflammation and Immunity, Gastroenterology & Hepatology, Cleveland Clinic, Cleveland, OH, USA., Gopan A; KEM Hospital, Seth GS Medical College, Mumbai, India., Goudarzi M; Respiratory Medicine, Cleveland Clinic, Cleveland, Ohio, USA., King J; Departments of Inflammation and Immunity, Gastroenterology & Hepatology, Cleveland Clinic, Cleveland, OH, USA., Luknis M; Departments of Inflammation and Immunity, Gastroenterology & Hepatology, Cleveland Clinic, Cleveland, OH, USA., Musich R; Departments of Inflammation and Immunity, Gastroenterology & Hepatology, Cleveland Clinic, Cleveland, OH, USA., Agrawal V; Departments of Inflammation and Immunity, Gastroenterology & Hepatology, Cleveland Clinic, Cleveland, OH, USA., Bena J; Quantitative Health, Cleveland Clinic, Cleveland, Ohio, USA., Koch CJ; Department of Radiation Oncology, Philadelphia, PA, USA., Li L; Proteomics and Metabolomics Core, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA., Willard B; Proteomics and Metabolomics Core, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA., Shah YM; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA., Dasarathy S; Departments of Inflammation and Immunity, Gastroenterology & Hepatology, Cleveland Clinic, Cleveland, OH, USA.

Publikováno v: The Journal of physiology [J Physiol] 2024 Jun; Vol. 602 (12), pp. 2763-2806. Date of Electronic Publication: 2024 May 18.

Multivariate investigation of aging in mouse models expressing the Alzheimer's protective APOE2 allele: integrating cognitive metrics, brain imaging, and blood transcriptomics.

Autor: Moon HS; Department of Biomedical Engineering, Duke University, Durham, NC, USA.; Quantitative Imaging and Analysis Laboratory, Department of Radiology, Duke University School of Medicine, Durham, NC, USA., Mahzarnia A; Quantitative Imaging and Analysis Laboratory, Department of Radiology, Duke University School of Medicine, Durham, NC, USA., Stout J; Brain Imaging and Analysis Center, Duke University School of Medicine, Durham, NC, USA., Anderson RJ; Quantitative Imaging and Analysis Laboratory, Department of Radiology, Duke University School of Medicine, Durham, NC, USA., Strain M; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA., Tremblay JT; Quantitative Imaging and Analysis Laboratory, Department of Radiology, Duke University School of Medicine, Durham, NC, USA., Han ZY; Quantitative Imaging and Analysis Laboratory, Department of Radiology, Duke University School of Medicine, Durham, NC, USA., Niculescu A; Quantitative Imaging and Analysis Laboratory, Department of Radiology, Duke University School of Medicine, Durham, NC, USA., MacFarlane A; Department of Neuroscience, Duke University, Durham, NC, USA., King J; Department of Biomedical Engineering, Duke University, Durham, NC, USA., Ashley-Koch A; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA., Clark D; Quantitative Imaging and Analysis Laboratory, Department of Radiology, Duke University School of Medicine, Durham, NC, USA., Lutz MW; Department of Neurology, Duke University School of Medicine, Durham, NC, USA., Badea A; Department of Biomedical Engineering, Duke University, Durham, NC, USA. alexandra.badea@duke.edu.; Quantitative Imaging and Analysis Laboratory, Department of Radiology, Duke University School of Medicine, Durham, NC, USA. alexandra.badea@duke.edu.; Brain Imaging and Analysis Center, Duke University School of Medicine, Durham, NC, USA. alexandra.badea@duke.edu.; Department of Neurology, Duke University School of Medicine, Durham, NC, USA. alexandra.badea@duke.edu.

Publikováno v: Brain structure & function [Brain Struct Funct] 2024 Jan; Vol. 229 (1), pp. 231-249. Date of Electronic Publication: 2023 Dec 13.