Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jasmine Gore"'
CD200 ectodomain shedding into the tumor microenvironment leads to NK cell dysfunction and apoptosis
Autor:
Huw J. Morgan, Elise Rees, Simone Lanfredini, Kate A. Powell, Jasmine Gore, Alex Gibbs, Charlotte Lovatt, Gemma E. Davies, Carlotta Olivero, Boris Y. Shorning, Giusy Tornillo, Alex Tonks, Richard Darley, Eddie C.Y. Wang, Girish K. Patel
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 21 (2022)
The basis of immune evasion, a hallmark of cancer, can differ even when cancers arise from one cell type such as in the human skin keratinocyte carcinomas: basal and squamous cell carcinoma. Here we showed that the basal cell carcinoma tumor–initia
Externí odkaz:
https://doaj.org/article/ea703a273eba40cda8c0b9d20462893e
Autor:
David Granger, Patricia Henne, Annalisa Baccaro, Dinusha Fernando, Jasmine Gore, Ephraim Gbajumo, Vincent Muczynski, Mittal Shah, Kieran O'Donovan, Kerry Chester, Amit C. Nathwani
Publikováno v:
Blood. 140:7810-7811
Autor:
Elise Rees, Jasmine Gore
Publikováno v:
British Journal of Dermatology. 187:60-60
Autor:
Mittal Shah, David Granger, Tomasz Bobrzynski, Annalisa Baccaro, Jasmine Gore, Vincent Muczynski, Sarah Cook, Kerry Chester, Toby Batten, Kieran O'Donovan, Parag Jasani, Amit C. Nathwani
Publikováno v:
Journal of Clinical Oncology. 40:e19505-e19505
e19505 Background: Receptor tyrosine kinase-like Orphan Receptor-1 (ROR1) is widely expressed on hematological and solid tumors. NVG-111, a first in class humanized tandem scFv ROR1xCD3 bispecific antibody elicits potent killing of ROR1+ tumor cells
Autor:
David Granger, Shivam Bhatt, Patricia Henne, Annalisa Baccaro, Dinusha Fernando, Jasmine Gore, Ephraim Gbajumo, Kieran O'Donovan, Kerry Chester, Amit C. Nathwani
Publikováno v:
Journal of Clinical Oncology. 40:e14505-e14505
e14505 Background: NVG-111, a T cell engager (TCE) targeting ROR1 and CD3, is in clinical development for the treatment of Chronic Lymphocytic Leukemia (CLL) and Mantle Cell Leukemia (MCL). This 55KDa molecule consisting of humanised tandem scFvs is
Autor:
Kieran O'Donovan, Shivam Bhatt, Annalisa Baccaro, Dinusha Fernando, Angel Smith, Ephraim Gbajumo, Tomasz Bobrzynski, Jenny McIntosh, Jasmine Gore, Amit C. Nathwani, Kerry Chester, David Granger
Publikováno v:
Journal of Clinical Oncology. 40:e14506-e14506
e14506 Background: Bispecific antibodies provide an opportunity to treat a diverse range of disorders because of their ability to simultaneously attenuate several different pathways precisely and effectively, thus overcoming many of the limitations o