Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Jasmina S Redzic"'
Autor:
Jasmina S Redzic, Agnieszka A Kendrick, Karim Bahmed, Kristin D Dahl, Chad G Pearson, William A Robinson, Steven E Robinson, Michael W Graner, Elan Z Eisenmesser
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71225 (2013)
Extracellular vesicles (EVs) are key contributors to cancer where they play an integral role in cell-cell communication and transfer pro-oncogenic molecules to recipient cells thereby conferring a cancerous phenotype. Here, we purified EVs using stra
Externí odkaz:
https://doaj.org/article/9b10f7f1fb554169969def960004fa66
Autor:
Sam Fulte, Brianna Atto, Arianna McCarty, Kadi J. Horn, Jasmina S. Redzic, Elan Eisenmesser, Michael Yang, Robyn L. Marsh, Stephen Tristram, Sarah E. Clark
Publikováno v:
mSphere, Vol 9, Iss 3 (2024)
ABSTRACTIron acquisition is a key feature dictating the success of pathogen colonization and infection. Pathogens scavenging iron from the host must contend with other members of the microbiome similarly competing for the limited pool of bioavailable
Externí odkaz:
https://doaj.org/article/81c7fffd5ac842859cbbd250170577ce
Autor:
Jasmina S. Redzic, Jeremy Rahkola, Norman Tran, Todd Holyoak, Eunjeong Lee, Antonio Javier Martín-Galiano, Nancy Meyer, Hongjin Zheng, Elan Eisenmesser
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
Cryo-EM reveals the structure of the IgA1 metalloprotease (IgA1P) from the pathogen, G. haemolysans in the absence and presence of IgA substrate, which suggests a conserved gating mechanism for IgA1P enzymes and provides a basis for therapeutic strat
Externí odkaz:
https://doaj.org/article/aecc7e57ffe1489da8ea742c3f9074ec
Autor:
Eunjeong Lee, Matthew J. McLeod, Jasmina S. Redzic, Barbara Marcolin, Robert E. Thorne, Pratul Agarwal, Elan Zohar Eisenmesser
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Biliverdin Reductase B (BLVRB) is an NADPH-dependent reductase that catalyzes the reduction of multiple substrates and is therefore considered a critical cellular redox regulator. In this study, we sought to address whether both structural and dynami
Externí odkaz:
https://doaj.org/article/d7b85ee18a9f4b2a81e64a103cab008c
Autor:
Zhiming Wang, Jeremy Rahkola, Jasmina S. Redzic, Ying-Chih Chi, Norman Tran, Todd Holyoak, Hongjin Zheng, Edward Janoff, Elan Eisenmesser
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Pathogenic IgA1 metalloproteases block the initial host immune response by cleaving host IgA1. Using cryoEM, the authors here provide structural insights into the substrate recognition mechanism of Streptococcus pneumoniae IgA1 protease, and develop
Externí odkaz:
https://doaj.org/article/3a150d834bc14865bfd27cc7c6569711
Autor:
Eunjeong Lee, Jasmina S. Redzic, Travis Nemkov, Anthony J. Saviola, Monika Dzieciatkowska, Kirk C. Hansen, Angelo D’Alessandro, Charles Dinarello, Elan Z. Eisenmesser
Publikováno v:
Molecules, Vol 27, Iss 14, p 4494 (2022)
Toll-interleukin receptor (TIR) domains have emerged as critical players involved in innate immune signaling in humans but are also expressed as potential virulence factors within multiple pathogenic bacteria. However, there has been a shortage of st
Externí odkaz:
https://doaj.org/article/d24b68bd4a8d449685f8cbbcd76342ea
Autor:
Jasmina S. Redzic, Michael R. Duff, Ashley Blue, Todd M. Pitts, Pratul Agarwal, Elan Zohar Eisenmesser
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
The biliverdin reductase B (BLVRB) class of enzymes catalyze the NADPH-dependent reduction of multiple flavin substrates and are emerging as critical players in cellular redox regulation. However, the role of dynamics and allostery have not been addr
Externí odkaz:
https://doaj.org/article/ee672be1a0f340ee8b3426730e2bf8ca
Autor:
Travis Nemkov, Davide Stefanoni, Aarash Bordbar, Aaron Issaian, Bernhard O. Palsson, Larry J. Dumont, Ariel Hay, Anren Song, Yang Xia, Jasmina S. Redzic, Elan Z. Eisenmesser, James C. Zimring, Steve Kleinman, Kirk C. Hansen, Michael P. Busch, Angelo D’Alessandro, the Recipient Epidemiology and Donor Evaluation Study III Red Blood Cell–Omics (REDS-III RBC-Omics) Study
Publikováno v:
JCI Insight, Vol 6, Iss 3 (2021)
Computational models based on recent maps of the RBC proteome suggest that mature erythrocytes may harbor targets for common drugs. This prediction is relevant to RBC storage in the blood bank, in which the impact of small molecule drugs or other xen
Externí odkaz:
https://doaj.org/article/10ef3ba194d24381b742b21602b2835e
Autor:
Erik Klontz, Juliet O. Obi, Yajing Wang, Gabrielle Glendening, Jahid Carr, Constantine Tsibouris, Sahthi Buddula, Shreeram Nallar, Alexei S. Soares, Dorothy Beckett, Jasmina S. Redzic, Elan Eisenmesser, Cheyenne Palm, Katrina Schmidt, Alexis H. Scudder, Trinity Obiorah, Kow Essuman, Jeffrey Milbrandt, Aaron Diantonio, Krishanu Ray, Daniel Deredge, M LD. Snyder, Greg A. Snyder
Toll-like and Interleukin-1/18 receptor resistance (TIR) domain-containing proteins function as important signaling and immune regulatory molecules. TIR domain-containing proteins identified in eukaryotic and prokaryotic species also exhibit NAD+ hyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95374451370e60151b3cff10b9ddcf36
https://doi.org/10.1101/2023.05.19.541320
https://doi.org/10.1101/2023.05.19.541320
Autor:
Alberto Dinarello, Makenna May, Jesus Amo-Aparicio, Tania Azam, Joseph M Gaballa, Carlo Marchetti, Annachiara Tesoriere, Rachele Ghirardo, Jasmina S Redzic, William Webber, Shaikh M Atif, Suzhao Li, Elan Z Eisenmesser, Dennis M de Graaf, Charles A Dinarello
The IL-1 Family member IL-38 has been characterized primarily as an anti-inflammatory cytokine in human and mouse models of systemic diseases. Here, we examined the role of IL-38 in the murine small intestine (SI). Immunostaining of SI revealed that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79c6c3cc241b5c18735944c9d445e9ab
https://doi.org/10.1101/2023.04.04.535251
https://doi.org/10.1101/2023.04.04.535251