Identification of Heteroreceptors Complexes and Signal Transduction Events Using Bioluminescence Resonance Energy Transfer (BRET)

Autor: Irene Reyes-Resina, Jasmina Jiménez, Gemma Navarro, Rafael Franco

Publikováno v: Bio-Protocol, Vol 9, Iss 19 (2019)

Detecting protein-protein interactions by co-immunoprecipitation provided a major advancement in the immunology research field. In the G-protein-coupled receptors (GPCRs) research field, colocalization and co-immunoprecipitation were used to detect i

Externí odkaz: https://doaj.org/article/53ca1e71991e4988bebd079cb33af6d2

Potentiation of cannabinoid signaling in microglia by adenosine A 2A receptor antagonists

Autor: Carlos A. Saura, Verónica Sánchez de Medina, Dasiel O. Borroto-Escuela, Rafael Franco, Kjell Fuxe, Iu Raïch, Carlos Ferreiro-Vera, Gemma Navarro, Enric I. Canela, Anna Del Ser-Badia, Jasmina Jiménez, David Aguinaga, Irene Reyes-Resina, Alejandro Lillo

Publikováno v: Glia. 67:2410-2423

Neuroprotective M2-skewed microglia appear as promising to alter the course of neurodegenerative diseases and G protein-coupled receptors (GPCRs) are potential targets to achieve such microglial polarization. A common feature of adenosine A2A (A2A R)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5a2de88f03ceb1f2386544ce51356c9b
https://doi.org/10.1002/glia.23694

Expression of Melatonin and Dopamine D3 Receptor Heteromers in Eye Ciliary Body Epithelial Cells and Negative Correlation with Ocular Hypertension

Autor: Rafael Franco, Jesús Pintor, Jasmina Jiménez, Irene Reyes-Resina, Juan Sanchez-Naves, Jaume Lillo, Hanan Awad Alkozi, Anna Del Ser-Badia, Gemma Navarro

Publikováno v: Cells
Volume 9
Issue 1
Dipòsit Digital de la UB
Universidad de Barcelona
Cells, Vol 9, Iss 1, p 152 (2020)
Cells, 9(1):152
E-Prints Complutense. Archivo Institucional de la UCM
instname
E-Prints Complutense: Archivo Institucional de la UCM
Universidad Complutense de Madrid

Background: Experiments in the late nineties showed an inverse relationship in the eye levels of melatonin and dopamine, thereby constituting an example of eye parameters that are prone to circadian variations. The underlying mechanisms are not known

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::155a19e8dc825622f824684f5fe6ebc3

Increased expression of cannabinoid CB2 and serotonin 5-HT1A heteroreceptor complexes in a model of newborn hypoxic-ischemic brain damage

Autor: Nadine Jagerovic, Irene Reyes-Resina, José Martínez-Orgado, Rafael Franco, Ana Gutiérrez-Rodríguez, Paula Morales, Jasmina Jiménez, Gemma Navarro, María Villa

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

Preclinical work shows cannabidiol as a promising drug to manage neonatal hypoxic-ischemic brain damage (NHIBD). The molecular mechanism is not well defined but the beneficial effects of this phytocannabinoid are blocked by antagonists of both cannab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ff54fd47d15226b35de7a465522c89
http://hdl.handle.net/10261/185949

Differential effect of amphetamine over the corticotropin-releasing factor CRF

Autor: Gemma, Navarro, Mireia, Medrano, David, Aguinaga, Ignacio, Vega-Quiroga, Alejandro, Lillo, Jasmina, Jiménez, Mireia, Casanovas, Enric I, Canela, Josefa, Mallol, Katia, Gysling, Rafael, Franco

Publikováno v: Neuropharmacology. 152

Stress is one of the factors underlying drug seeking behavior that often goes in parallel with loss of appetite. We here demonstrate that orexin 1 receptors (OX

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dd5c04918874a98af3193e1268319787
https://pubmed.ncbi.nlm.nih.gov/30465812