Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Jasmin Straube"'
Autor:
Hyun Jae Lee, Marcela L. Moreira, Shihan Li, Takahiro Asatsuma, Cameron G. Williams, Oliver P. Skinner, Saba Asad, Michael Bramhall, Zhe Jiang, Zihan Liu, Ashlyn S. Kerr, Jessica A. Engel, Megan S. F. Soon, Jasmin Straube, Irving Barrera, Evan Murray, Fei Chen, Jason Nideffer, Prasanna Jagannathan, Ashraful Haque
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Children in malaria-endemic regions can experience repeated Plasmodium infections over short periods of time. Effects of re-infection on multiple co-existing CD4+ T cell subsets remain unresolved. Here, we examine antigen-experienced CD4+ T
Externí odkaz:
https://doaj.org/article/4d3cc96140c047edad0a1f3a0d29e9e7
Autor:
Janelle L. Hancock, Murugan Kalimutho, Jasmin Straube, Malcolm Lim, Irma Gresshoff, Jodi M. Saunus, Jason S. Lee, Sunil R. Lakhani, Kaylene J. Simpson, Ashley I. Bush, Robin L. Anderson, Kum Kum Khanna
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-16 (2023)
Abstract Background Despite overall improvement in breast cancer patient outcomes from earlier diagnosis and personalised treatment approaches, some patients continue to experience recurrence and incurable metastases. It is therefore imperative to un
Externí odkaz:
https://doaj.org/article/d9fe64d800bf4622bdc3d1e38364ba23
Autor:
Rebecca J. Austin, Jasmin Straube, Rohit Halder, Yashaswini Janardhanan, Claudia Bruedigam, Matthew Witkowski, Leanne Cooper, Amy Porter, Matthias Braun, Fernando Souza-Fonseca-Guimaraes, Simone A. Minnie, Emily Cooper, Sebastien Jacquelin, Axia Song, Tobias Bald, Kyohei Nakamura, Geoffrey R. Hill, Iannis Aifantis, Steven W. Lane, Megan J. Bywater
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Acute myeloid leukemia (AML) is a genetically heterogeneous, aggressive hematological malignancy induced by distinct oncogenic driver mutations. The effect of specific AML oncogenes on immune activation or suppression is unclear. Here, we ex
Externí odkaz:
https://doaj.org/article/1fe1b18939ee4e878a49fa928f9e503d
Autor:
Jasmin Straube, Steven W. Lane
Publikováno v:
Haematologica, Vol 108, Iss 8 (2023)
Externí odkaz:
https://doaj.org/article/4443eef1348942fdb3cea5fff3761ca4
Autor:
Aleksandra Boikova, Megan J. Bywater, Gregory A. Quaife-Ryan, Jasmin Straube, Lucy Thompson, Camilla Ascanelli, Trevor D. Littlewood, Gerard I. Evan, James E. Hudson, Catherine H. Wilson
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
AimAdult mammalian cardiomyocytes are incapable of significant proliferation, limiting regeneration after myocardial injury. Overexpression of the transcription factor Myc has been shown to drive proliferation in the adult mouse heart, but only when
Externí odkaz:
https://doaj.org/article/d71cec92c0694be39048a32153f4f165
Autor:
Therese Vu, Jasmin Straube, Amy H. Porter, Megan Bywater, Axia Song, Victoria Ling, Leanne Cooper, Gabor Pali, Claudia Bruedigam, Sebastien Jacquelin, Joanne Green, Graham Magor, Andrew Perkins, Alistair M. Chalk, Carl R. Walkley, Florian H. Heidel, Pamela Mukhopadhyay, Nicole Cloonan, Stefan Gröschel, Jan-Philipp Mallm, Stefan Fröhling, Claudia Scholl, Steven W. Lane
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The caudal-related homeobox transcription factor CDX2 is expressed in leukemic cells in the majority of patients with leukemia but not during normal blood formation. Here, the authors report a mouse model with conditional Cdx2 expression showing de n
Externí odkaz:
https://doaj.org/article/bceafc18d13641ee9c5212ab1db8af73
Autor:
Megan J. Bywater, Deborah L. Burkhart, Jasmin Straube, Arianna Sabò, Vera Pendino, James E. Hudson, Gregory A. Quaife-Ryan, Enzo R. Porrello, James Rae, Robert G. Parton, Theresia R. Kress, Bruno Amati, Trevor D. Littlewood, Gerard I. Evan, Catherine H. Wilson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Levels of the transcription factor Myc are deregulated in a range of different cancers. Here the authors show that Myc induces rapid transcriptional responses in some mouse tissues (liver), but not others (heart), and that transcriptional and prolife
Externí odkaz:
https://doaj.org/article/6242a1a22a8f47f48a5d16c07381d895
Autor:
Harshi Weerakoon, Jasmin Straube, Katie Lineburg, Leanne Cooper, Steven Lane, Corey Smith, Saleh Alabbas, Jakob Begun, John J Miles, Michelle M Hill, Ailin Lepletier
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 9, Pp n/a-n/a (2021)
Abstract Objective Adoptive regulatory T cell (Treg) therapy is being trialled for the treatment of different autoimmune disorders, including inflammatory bowel diseases (IBD). In‐depth understanding of the biological variability of Treg in the hum
Externí odkaz:
https://doaj.org/article/0c2abdfe537247e28172990f1bb11761
Publikováno v:
Cells, Vol 9, Iss 8, p 1901 (2020)
Myeloproliferative neoplasms (MPNs) constitute a group of disorders identified by an overproduction of cells derived from myeloid lineage. The majority of MPNs have an identifiable driver mutation responsible for cytokine-independent proliferative si
Externí odkaz:
https://doaj.org/article/8ad9019407194270a573dd5debfff797
Autor:
Rochelle C. J. D’Souza, Carolin Offenhäuser, Jasmin Straube, Ulrich Baumgartner, Anja Kordowski, Yuchen Li, Brett W. Stringer, Hamish Alexander, Zarnie Lwin, Po-Ling Inglis, Rosalind L. Jeffree, Terrance G. Johns, Andrew W. Boyd, Bryan W. Day
Publikováno v:
Cells, Vol 9, Iss 2, p 267 (2020)
Glioblastoma (GBM) is a treatment-refractory central nervous system (CNS) tumour, and better therapies to treat this aggressive disease are urgently needed. Primary GBM models that represent the true disease state are essential to better understand d
Externí odkaz:
https://doaj.org/article/2b1cf0726612426c9ffab03008cd9431